2019-11-04 16:49
New research shows that protein-based biosensors can detect the presence of a desired enzyme target and respond by physically lighting up and enabling researchers to immediately identify cel… Read More
Blog Directory > Education Blogs > Higher Education Blogs > Pharmaceutical Microbiology higher-education Blog >
Pharmaceutical Microbiology Blog
pharmamicroresources.com
Tags:
tim sandle
fatty liver disease
physical
national laboratory
nature chemistry
haem
fungal
bacteria
distribution practice
mrsa strains
pharmaceutical microbiology,quality assurance, healthcare, cleanroom, contamination control, microbiology, tim sandle, sterility, disinfection
2019-11-03 18:14
An excellent new two-volume book has been published, vital for those working in pharmaceuticals and healthcare:Good Distribution Practice: A Handbook for Healthcare Manufacturers and Supplie… Read More
2019-11-03 09:30
Researchers have demonstrated a new strategy in fighting antibiotics resistance: the use of artificial haem proteins as a Trojan horse to selectively deliver antimicrobials to target bacteri… Read More
2019-11-02 11:00
Non-alcoholic fatty liver disease (NAFLD) is the build-up of fat in the liver due to factors other than alcohol. It affects about a quarter of the adult population globally, but its cause re… Read More
2019-11-01 12:30
Findings from an innovative new study led by researchers at Dartmouth's Geisel School of Medicine and published this week in Nature Microbiology reveal that the way in which human fungal pat… Read More
2019-10-30 12:00
The healthcare industry is experiencing rapid change as a result of new technologies. With physical therapy being one field that is seeing some of the most significant changes, patient care… Read More
2019-10-29 13:30
A new study, published today in eLife. The findings in mice reveal how mucosal infections, specifically bladder infections, can rewire inflammatory responses driven by a protein called tumou… Read More
2019-10-27 10:15
A new study from EPFL scientists has found that bacteria use mechanical forces to divide, along with biological factors. The research, led by the groups of John McKinney and Georg Fantner at… Read More
2019-10-26 11:00
One of the WHO's three critical priority pathogens, Acinetobacter baumannii, for which new antibiotics are urgently needed is one step closer to being tackled, as researchers from the Depart… Read More
2019-10-25 11:30
The novel small molecules, based on new target, new chemical structure and new antimicrobial mechanism, are different from those of existing antibiotics. The new drug candidates demonstrate… Read More
2019-10-24 11:00
Immunodeficiency is the condition where the capability of the immune system to fight against diseases has been compromised. Immunocompromised people have a higher chance of contacting diseas… Read More
2019-10-23 11:30
Scientists have found exceptionally preserved microbial remains in some of Earth's oldest rocks in Western Australia -- a major advance in the field, offering clues for how life on Earth ori… Read More
2019-10-22 11:00
A new standard has been issued:“This document gives guidance and recommendations for optimizing energy usage and maintaining energy efficiency in new and existing cleanrooms, clean zon… Read More
2019-10-21 11:49
Audit and Control for Healthcare Manufacturers” by Tim and Jennifer Sandle (published by DHI, http://www.dhibooks.com/books/17351.html)Robust Quality Audits Are T... by Tim Sandle on S… Read More
2019-10-20 11:30
Bacteria can change form in human body, hiding the cell wall inside themselves to avoid detection. The cell wall is often the antibiotic target - so if bacteria are concealing it inside them… Read More
2019-10-19 11:00
The Columbia team behind the revolutionary 3D SCAPE microscope announces today a new version of this high-speed imaging technology. In collaboration with scientists from around the world, th… Read More
2019-10-18 12:00
Investigators have identified a washing machine as a reservoir of multidrug-resistant pathogens. The pathogens, a single clone of Klebsiella oxytoca, were transmitted repeatedly to newborns… Read More
2019-10-17 11:00
Free-to-read article on microbial culture media best practices.The Use of Microbiological ... by Tim Sandle on ScribdPosted by Dr. Tim Sandle, Pharmaceutical MicrobiologyPharmaceutical Micr… Read More
2019-10-16 12:00
A discovery by researchers at the School of Life Sciences at the University of Warwick offers a new technology for detecting bacteria in minutes by 'zapping' the bacteria with electricity.Te… Read More
2019-10-15 12:00
Solubility is one of the most important phenomena in chemistry, pharmaceuticals and any number of other disciplines and industries. In the development of drugs, the ability of a solvent to c… Read More
2019-10-14 11:30
As with other sectors of the economy, pharmaceuticals and healthcare is undergoing digital transformation and with some companies this is continuing at a rapid pace as companies attempt to m… Read More
2019-10-13 12:30
The U.S. FDA requires reporting of certain deviations and unexpected events in manufacturing in accordance with 21 CFR 600.14, 606.171 or 1271.350(b). The following manufacturers, who… Read More
2019-10-12 12:00
A new part of the ISO 14644 series is in development – ‘ISO/DIS 14644-17Cleanrooms and associated controlled environments -- Part 17: Particle deposition rate applications’… Read More
2019-10-12 11:00
The MHRA has issued a feature on the application of Analytical Quality by Design to pharmacopoeial standards.Analytical Quality by Design (AQbD) takes a structured approach to the developmen… Read More
2019-10-11 12:30
National Institute of Allergy and Infectious Diseases (NIAID) experts call for a renewed focus on sexually transmitted infections. Rates of gonorrhea, syphilis, and chlamydia are all on the… Read More
2019-10-10 10:30
Crude oil and gas naturally escape from the seabed in many places known as "seeps." There, these hydrocarbons move up from source rocks through fractures and sediments towards the surface, w… Read More
2019-10-09 10:00
Most types of Escherichia coli are harmless, but the ones that aren't can cause severe life-threatening diarrhea. These problematic bacteria launch infections by inducing intestinal cells to… Read More
2019-10-08 11:00
New DNA analysis has found genetic diversity in Vampirovibrio chlorellevorus, complicating efforts to protect algae ponds and the biofuels industry from this destructive pestNew DNA analysis… Read More
2019-10-07 11:00
There are many excellent science studies based on well-designed experiments and which make reasoned claims based on the assembled experimental data. While the majority of scientific findings… Read More
2019-10-06 12:00
Pathogenic bacteria that stubbornly lurk in some apple-packing facilities may be sheltered and protected by harmless bacteria that are known for their ability to form biofilms, according to… Read More
2019-10-05 12:00
More than 60% of women will experience a urinary tract infection (UTI) at some point in their lives, and about a quarter will get a second such infection within six months, for reasons that… Read More
2019-10-04 12:00
Interdisciplinary interactions are essential for driving the innovation pipeline in biological imaging, yet collegial workspaces where they can spring up and mature are lacking in the United… Read More
2019-10-03 13:00
The US Food and Drug Administration (FDA) today approved a combination regimen containing a new drug, pretomanid, for the treatment of extensively drug-resistant tuberculosis (XDR-TB). As t… Read More
2019-10-02 11:30
Harmonizing Compendial Standards With Drug Application Approval Using the USP Pending Monograph Process - new FDA Guidance for Industry.This guidance assists applicants and drug master… Read More
2019-10-01 12:30
A Netherlands Cancer Institute team, co-led by Thijn Brummelkamp and Anastassis (Tassos) Perrakis, reported independently, but almost simultaneously with three more groups from all over the… Read More
2019-09-30 11:30
For conventional culture based microbial methods and with many rapid and alternative microbiological methods, the way that method suitability is demonstrated is with the recovery of known po… Read More
2019-09-29 11:00
A new study examines the evolutionary dynamics of circular Rep-encoding single-stranded (CRESS) DNA viruses. The findings show that this broad class of single-stranded DNA viruses, which inf… Read More
2019-09-28 11:30
Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining. Researchers have used t… Read More
2019-09-27 11:30
The evolution of more severe infections is not necessarily driven by bacteria multiplying faster, new research shows. Humans and animals can develop resistance to harmful bacteria (pathogens… Read More
2019-09-26 11:57
In the ongoing fight against antibiotic resistance, NIAID supports studies of new therapeutics, as well as new uses for older, established antibiotics. In a new study, NIAID-supported resear… Read More
2019-09-25 12:30
A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modifica… Read More
2019-09-24 11:30
An all-female team of doctors has developed a revolutionary new formula to aid the millions of women around the world suffering from Bacterial Vaginosis following extensive research and gene… Read More
2019-09-23 12:00
A new research paper of interest:A novel mechanism of action of ketoconazole: inhibition of the NorA efflux pump system and biofilm formation in multidrug-resistant Staphylococcus aureusBack… Read More
2019-09-22 11:30
The British Pharmacopeia (BP) and the United States Pharmacopeia (USP) formalized their long-standing partnership to strengthen the quality of medicines and improve public health around the… Read More
2019-09-21 11:30
The new trial will be led by the U.K. National Institute for Health and Care Excellence (NICE) and NHS England and NHS Improvement. It will test a ‘subscription’ style model that… Read More
2019-09-20 11:33
For nearly a century, evolutionary biologists have probed how genes encode an individual's chances for success -- or fitness -- in a specific environment.In order to reveal a potential evolu… Read More
2019-09-19 21:48
Symposium - Animal Welfare in Pharma Join us at a symposium to celebrate the 60th anniversary of the 3Rs guiding principles (Reduction, Refinement and Replacement) for ethical use of animals… Read More
2019-09-19 11:30
With the recognition by the US Food and Drug Administration (FDA) of Slovakia, the European Union and the United States have now fully implemented the mutual recognition agreement (MRA) for… Read More
2019-09-18 11:00
Algae blooms regularly make for pretty, swirly satellite photos of lakes and oceans. They also make the news occasionally for poisoning fish, people and other animals. What's less frequently… Read More
2019-09-17 11:30
Image: Supriya GhugeSummary: The global healthcare archiving and eDiscovery market is expected to experience a surge in demand due to the shift from legacy to digitized formats. Data governa… Read More
2019-09-16 11:00
Sterile medicinal products can be produced by one of two methods: terminal sterilisation (which is the method of choice for regulators) or aseptic processing (which carries greater inherent… Read More
2019-09-15 11:00
There are numerous different scenarios in which microorganisms are exposed to highly reactive molecules known as free radicals. These molecules are capable of damaging important cell compone… Read More
2019-09-14 11:00
A new study from Aarhus University Hospital and Aarhus University, Denmark, has shown that probably 1 in 4 people in the world carry the tuberculosis bacterium in the body. The disease tuber… Read More
2019-09-13 11:30
Exposure to C. difficile in infancy produces an immune response that might protect against this gastrointestinal infection later in childhood. Researchers found that infants who were natural… Read More
2019-09-12 08:33
Weighing balances are an important part of the equipment used in analytical laboratories, even if the lab isn’t equipped with a wide range of analytical instruments. Weighing is involv… Read More
2019-09-11 12:00
Details of the tenth edition of the European Pharmacopeia have been published. The European Pharmacopoeia (Ph. Eur.) is a single reference work for the quality control of medicines. The offi… Read More
2019-09-10 11:30
Future of computing?In order to create new and more efficient computers, medical devices, and other advanced technologies, researchers are turning to nanomaterials: materials manipulated on… Read More
2019-09-09 11:00
Despite much discussion about the subject over the past 3 years, in particular, data integrity issues remain a common feature on 483 letters issued by the USA Food and Drug Administration (F… Read More
2019-09-08 11:00
Dengue virus (DENV) causes infection in humans and current estimates place 40% of the world population at risk for contracting disease.An article of interest:There are four DENV serotypes th… Read More
2019-09-07 11:00
Why is drug resistance common and vaccine resistance rare? Drugs and vaccines both impose substantial pressure on pathogen populations to evolve resistance and indeed, drug resistance typica… Read More
2019-09-06 11:00
PanTheryx, a biotechnology company focused on addressing serious GI related health conditions, announced today that it has completed $50 million in new financing with Perceptive Advisors. Pr… Read More
2019-09-05 20:37
When an individual is sick, they might feel it problematic to develop a hunger. Though it is significant to obtain suitable food and stay hydrated, particularly when feeling unwell. Cold is… Read More
2019-09-05 11:00
Plague has a long history on the European continent, with evidence of the disease dating back to the Stone Age. Plague epidemics in Europe during the First and Second Pandemics, including th… Read More
2019-09-04 11:00
Most microbes are inside the apple – but the strains depend on which bits you eat,and whether you go organicTo the heroes among you who eat the whole apple: besides extra fiber, flavon… Read More
2019-09-03 11:30
Influenza polymerase (light cyan) in the process of synthesising messenger RNA (slate blue) by copying the genomic viral RNA template (yellow). IMAGE: Stephen Cusack / EMBLWhen a virus infec… Read More
2019-09-02 12:00
The presence of endotoxin in sterile pharmaceutical products presents a significant risk to patients. The primary source of endotoxin is pharmaceutical grade water, due to the potential for… Read More
2019-09-01 11:30
In terms of what FDA CDER is planning to publish for the remainder of 2019, we can expect:CATEGORY – Blood and Blood Components: Implementation of Pathogen Reduction Technology in the… Read More
2019-08-31 11:30
Fecal transplantsOn June 13, 2019, the Food and Drug Administration (FDA) informed health care providers and patients of the potential risk of serious or life-threatening infections with the… Read More
2019-08-30 11:00
MSF/Doctors Without Borders Study: Non-Physician Clinicians in South Sudan Diagnose Children’s Pneumonia and Other Respiratory Diseases with Ultrasound Accurately After Short TrainingN… Read More
2019-08-29 11:30
Microbiology in action!Effective contamination control requires high-quality cleaning equipment and specialized techniques. It does not matter how effective a cleaning agent is if the cleani… Read More
2019-08-28 11:30
Crouching in the boot-sucking mud of the Baylands Nature Preserve in Palo Alto, Manu Prakash, associate professor of bioengineering at Stanford University, peered through his Foldscope -- a… Read More
2019-08-27 11:30
FDA’s Center for Drug Evaluation and Research (CDER) has embarked on an initiative to modernize the New Drugs Regulatory Program. This effort will allow CDER to better serve patients a… Read More
2019-08-26 11:30
Compliance is an affirmative indication or judgement that the supplier of a product or service has met the requirements of the relevant specifications, contract or regulation; al… Read More
2019-08-25 11:30
Yersinia plague bacteriumYersinia have spread fear and terror, especially in the past, but today the plague pathogens have still not been completely eradicated. The bacteria inject various e… Read More
2019-08-24 11:30
Not only are they effective against Gram-positive and negative multi-resistant bacteria, they also appear not to trigger resistance when used to treat infection in mice. Such are the promise… Read More
2019-08-23 11:30
Gram negative bacteria can cause diseases such as pneumonia, cholera, typhoid fever and E. coli infections, as well as many hospital acquired infections. They are increasingly resistant to a… Read More
2019-08-22 11:30
Research by scientists into why some bacteria have different shapes has found that a curved shape can make it easier to find food. Computer simulations were used to compare the swimming of d… Read More
2019-08-21 11:30
The results of two new reports, linking the growth of infants and children to healthy development of gut microbiomes, were published in Science on July 12th. Researchers utilized microbiome… Read More
2019-08-20 11:30
MHRA have released a summary of the recent Good Distribution Practice (GDP) Symposium. The focus of the 2018 GDP symposium was maintaining compliance in a changing world.One of the interesti… Read More
2019-08-18 16:29
India carefully monitors their healthcare services, so opening a pharma company in India can be a good business idea. In this guide, we will explain how to open a monopoly pharma franchise c… Read More
2019-08-18 11:00
There are a number of ways by which antimicrobial resistance can spread, and one that is of growing concern is the disposal of medicines by consumers down sinks and toilets. A new technique… Read More
2019-08-17 11:30
Microbiome research has advanced considerably since the first results from the U.S. National Institutes of Health led Human Microbiome Project were released. One area of interest is the conn… Read More
2019-08-16 11:30
The draft ICH guidance is currently out for review. This proposed new multidisciplinary guideline will address the validation of bioanalytical assays. This guideline will provide recommendat… Read More
2019-08-15 11:30
The European Medicines Agency’s (EMA) Committee for Advanced Therapies (CAT), together with the GMDP Inspectors Working Group and the Blood Products Working Party, have released a ques… Read More
2019-08-14 20:10
A new and important book has been released "Biotechnology: From Idea to Market", edited by Fred Mermelstein, Carl Novina, and Richard Prince.Biotechnology: From Idea to Market, is an invalua… Read More
2019-08-14 11:30
Nearly 36 percent of patients with a tick-borne disease spent more than $10,000 on tests, treatments, appointments, and other costs associated with their disease, a new IGeneX survey found… Read More
2019-08-13 13:00
Study Finds High-Tech Bednet Use Monitoring Tool Produces Detailed Data on Daily Usage, Offering a New Tool to Study Declining Efficacy In Malaria Prevention A new technology sewn into the l… Read More
2019-08-12 13:00
Sterile pharmaceutical products need to be manufactured to the highest possible standards and the technology, processes and regulatory expectations continue to shift. Understanding these cha… Read More
2019-08-11 11:30
What if the missing ‘environmental’ factor in some of our deadliest neurological diseases were really written in our genome?Writing in Frontiers in Genetics, researchers from the… Read More
2019-08-10 13:00
To see migrants dying while fleeing for their lives anywhere in the world is heartbreaking. The most recent picture of the Salvadoran father and his daughter face down on the banks of the Ri… Read More
2019-08-09 12:00
A paper of interest:Study title: 'Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD'The overuse and misuse of antib… Read More
2019-08-08 12:00
The FDA has issued a new guidance document, titled “Submitting Documents Using Real-World Data and Real-World Evidence to FDA for Drugs and Biologics.”This guidance is intended t… Read More
2019-08-07 12:00
Researchers have mapped the most common bacterial cause of pneumonia around the world and revealed how these bacteria evolve in response to vaccination. Scientists from the Wellcome Sanger I… Read More
2019-08-06 11:30
The U.S. FDA has issued a new guidance document: “Development of Therapeutic Protein Biosimilars: Comparative Analytical Assessment and Other Quality-Related Considerations.”Give… Read More
2019-08-05 13:00
Discovery of a new feature of a large class of pathogenic viruses may allow development of new antiviral medications for the common cold, polio, and other illnesses, according to a new study… Read More
2019-08-04 12:00
The U.S. FDA has issued a new guidance document “Considerations in Demonstrating Interchangeability With a Reference Product”. This guidance is intended to assist sponsors in dem… Read More
2019-08-03 12:30
Histology is an essential tool of biology and medicine; refers to the study of the anatomy of cells and tissues of plants and animals using microscopy. These aspects of human physiology are… Read More
2019-08-02 11:30
Clostridium difficile infections (CDI) are a serious threat to public health. This often-deadly pathogen is the leading cause of healthcare-associated infections in the United States, repres… Read More
2019-08-01 13:00
Nitric oxide (NO) is a central molecule of the global nitrogen cycle. A study reveals that microorganisms can grow on NO. Their results change our view of the earth's nitrogen cycle and how… Read More
2019-07-30 11:30
News from the Australian TGA, new guidance for tablets, capsules and pills (Guidance for TGO 101). This guidance is to help sponsors and manufacturers of medicines understand the role of the… Read More
Subscribe to Pharmaceutical Microbiology
Get updates delivered right to your inbox!