2019-01-21 20:43
Cleanroom contamination can arise from a number of sources. Most contamination within the pharmaceutical facility can be traced to humans working in cleanrooms. The paper discusses staff gow… Read More
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pharmaceutical microbiology,quality assurance, healthcare, cleanroom, contamination control, microbiology, tim sandle, sterility, disinfection
2019-01-20 12:30
The wide variety of organic and inorganic materials that comprise a painting, such as canvas, oil, pigments, and varnish, can provide an ideal environment for colonizing bacteria and fungi… Read More
2019-01-19 12:30
Under threat of being scrubbed away with disinfectant, individual bacteria can improve their odds of survival by joining together to form colonies, called biofilms. What Arnold Mathijssen, p… Read More
2019-01-18 13:30
The European Pharmacopoeia (Ph. Eur.) Commission is consulting its stakeholders on Ph. Eur. dosage form monograph on Parenteral preparations (0520) and new informative chapter on testing for… Read More
2019-01-17 13:00
Cell membranes are formed largely of a bimolecular sheet, a fraction of the thickness of a soap bubble, in which two layers of lipid molecules are packed with their hydrophobic tails pointin… Read More
2019-01-16 23:10
Pharmaceutical Microbiology (c) Dr Tim Sandle
http://www.pharmamicroresources.com Read More
2019-01-15 13:30
The European Pharmacopoeia (Ph. Eur.) Commission decided to restructure Section 3. of the Ph. Eur. on materials and containers. A new Subsection 3.3. has been added to Section 3. in order to… Read More
2019-01-14 13:00
The human body is an intricate system that hosts trillions of microbial cells across the epithelial surface, and within the mouth and gut. These microorganisms play a role in human physiolog… Read More
2019-01-13 13:30
Media that is bought into labs in a ready to go or Ready to Use (RTU) format goes by many different descriptions such as Ready Prepared Media, Pre-Plated Media/Pre-Poured Media (PPM), Ready… Read More
2019-01-12 13:30
Australia - Therapeutic Goods Order No.77 Microbiological standards for medicines (TGO 77) has been in force since 2010. It was automatically repealed (sunset) on 1 October 2018 in accordanc… Read More
2019-01-11 13:30
A revised Draft PIC/S Guidance on Good Practices for Data Management and Integrity in Regulated GMP/GDP Environments (PI 041-1 (Draft 3) has been prepared by the PIC/S Working Group on Data… Read More
2019-01-10 12:30
FDA has submitted a proposal to ICH recommending the development of internationally harmonized guidelines on scientific and technical standards for generic drugs. ICH is the global venue for… Read More
2019-01-09 13:30
At its 162nd Session in Strasbourg on 20-21 November 2018, the European Pharmacopoeia (Ph. Eur.) Commission adopted 16 new texts:Four general chapters: Quantification and characterisation of… Read More
2019-01-08 13:00
Within harsh environments like hot springs, volcanic craters and deep-sea hydrothermal vents -- uninhabitable by most life forms -- microscopic organisms are thriving. How? It's all in how t… Read More
2019-01-07 14:00
Controlled environments required for the manufacture of pharmaceutical products are cleanrooms and they are assigned a class through meeting a set standard for airborne particles. Once a gra… Read More
2019-01-06 14:00
The gut microbiome -- the world of microbes that inhabit the human intestinal tract -- has captured the interest of scientists and clinicians for its critical role in health. However, parsin… Read More
2019-01-05 13:30
An interesting post from ISO:“The world’s scientific community is making a fundamental change in how we measure things by redefining the kilogramme, the kelvin, the ampere and th… Read More
2019-01-04 13:30
Washing contaminated hospital bedsheets in a commercial washing machine with industrial detergent at high disinfecting temperatures failed to remove all traces of Clostridium difficile (C. d… Read More
2019-01-03 13:00
Different "events" such as infections by viruses, as well as the exposure to environmental toxins or other forms of stress, change the activity of genes thereby leaving molecular traces insi… Read More
2019-01-02 13:00
While studying viruses best known for infecting the brain, researchers at Washington University School of Medicine in St. Louis stumbled upon clues to a conundrum involving a completely diff… Read More
2018-12-30 13:30
A study led by Dr Emma Sweeney and Adjunct Associate Professor Christine Knox, from QUT's Institute of Health and Biomedical Innovation, with colleagues at the University of Queensland, show… Read More
2018-12-29 13:00
In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause t… Read More
2018-12-28 14:00
Microbiology is now an advanced scientific field, focusing on the study of various microscopic organisms like fungus, bacteria, virus, etc. Microbiology is used largely for research and diag… Read More
2018-12-27 13:30
An unprecedented comparison of hundreds of species of yeasts has helped geneticists brew up an expansive picture of their evolution over the last hundreds of millions of years, including an… Read More
2018-12-26 13:30
Most of us are aware of the seasonal cycle of influenza outbreaks, which for Americans peak in the winter. In a new paper, Micaela Martinez, PhD, a scientist at the Columbia Mailman School o… Read More
2018-12-25 13:00
The Microbiologics blog has a useful back-to-basics article on good pour plate practices. Included in the article is the following advice:1. Keep the molten agar in the water bath for no mor… Read More
2018-12-24 10:00
I'd like to wish all readers of Pharmaceutical Microbiology all the best wishes for the holiday season and thank you for supporting this website.Posted by Dr. Tim Sandle, Pharmaceutical Mic… Read More
2018-12-23 14:00
Brazil's Ministry of Health received reports of 11,524 outbreaks of foodborne diseases between 2000 and 2015, with 219,909 individuals falling sick and 167 dying from the diseases in questio… Read More
2018-12-22 14:00
The European Pharmacopoeia (Ph. Eur.) has launched a public consultation on its new general chapter 5.1.12 on depyrogenation of items used in the production of parenteral preparations. While… Read More
2018-12-21 14:00
Antibiotics resistance among bacteria (superbugs) is a large and growing problem, with huge health and economic consequences in the US and around the world. According to a new report issued… Read More
2018-12-20 23:39
Associates of Cape Cod, Inc. (ACC ), is pleased to announce an exciting new initiative aimed at complementing our 45 year history of horseshoe crab conservation. ACC introduces a Horseshoe C… Read More
2018-12-19 14:00
Mucormycosis is a drug-resistant fungal infection that attacks patients with weakened immune systems and those who have suffered significant trauma. The infection can be easily missed by phy… Read More
2018-12-18 14:00
The FDA continues to advance new policies, modernize our programs and advance opportunities for developing more targeted therapies. Using new technology platforms such as cell and gene thera… Read More
2018-12-17 13:00
Malaria-infectedred blood cells trigger the immune system's first line of defense by releasing small vesicles that activate a pathogen recognition receptor called MDA5, according to a study… Read More
2018-12-16 13:00
Scientists have turned to an unusual source in order to tackle the problem of pathogenic bacteria – oxygen. This is in relation to MRSA, which is associated with hospital derive infect… Read More
2018-12-15 13:00
Most of us take our water for granted. We are fortunate to have comprehensive systems in place such as municipal water purification facilities to remove all of the unwanted and unsafe substa… Read More
2018-12-14 23:25
There are biological, psychological and behavioral differences between genders that affect health. For example, women are more likely to be diagnosed with osteoporosis and men are more likel… Read More
2018-12-13 21:19
FDA has issued a new guidance document on data integrity “Data Integrity and Compliance With Drug CGMP Questions and Answers Guidance for Industry”.The introduction reads:“… Read More
2018-12-12 13:00
The European Medicines Agency (EMA) and the European Commission have published additional information material on biosimilar medicines, as part of their ongoing collaboration to improve unde… Read More
2018-12-11 13:00
Researchers are testing whether a light-active version of heme, the molecule responsible for transporting oxygen in blood circulation, may help people infected with MRSA. Photodynamic therap… Read More
2018-12-10 13:30
Tim Sandle has written a new chapter which reviews the use of disinfectants and biocides in the pharmaceutical and healthcare sectors. This is for a new book edited by Jeanne Moldenhauer tit… Read More
2018-12-09 13:30
Changing the way microbes are classified can reveal similarities among mammals' gut microbiomes, according to a new study. The study, published in mBio, proposed an alternative method for cl… Read More
2018-12-08 13:30
A team of researchers has now engineered a virus nanoparticle vaccine against Bacillus anthracis and Yersinia pestis, tier 1 agents that pose serious threats to national security of the Unit… Read More
2018-12-07 14:00
Allowing sunlight in through windows can kill bacteria that live in dust, according to a study published in the open access journal Microbiome.Researchers at the University of Oregon found t… Read More
2018-12-06 14:00
For any Pharmaceutical company, maintaining the desired standard quality of the pharmaceuticals from the storage to till the distribution is a challenging task. Therefore, special measures w… Read More
2018-12-05 13:55
Combioxin SA, a clinical-stage biotechnology company focused on the development of innovative treatments for severe and resistant infections, announced today that first-in-human clinical res… Read More
2018-12-04 13:30
Humans have always been curious about the power and significance of light. This curiosity is evident in ancient religious texts, paintings, literary works, and much more. In the world of lig… Read More
2018-12-03 13:00
The fifth edition of the PDA/DHI book, GMP in Practice: Regulatory Expectationsfor the Pharmaceutical Industry has been published. The PDA Letter interviewed authors Tim Sandle and James Ves… Read More
2018-12-02 11:24
Increasing inclination toward the use of high-grade polymer materials in the construction of single-use bioprocessing materials and development of advanced materials that can provide integra… Read More
2018-12-01 12:00
Alterations to the respiratory microbiome have been identified as a predisposing factor of interstitial lung diseases (ILD). In a new study, researchers studied the influence of bacterial vi… Read More
2018-11-30 12:30
The Earth Microbiome Project is a systematic attempt to characterize global microbial taxonomic and functional diversity for the benefit of the planet and humankind.The Earth Microbiome Proj… Read More
2018-11-29 12:30
A mushroom extract fed to honey bees greatly reduces virus levels, according to a new paper. In field trials, colonies fed mycelium extract showed a 79-fold reduction in deformed wing virus… Read More
2018-11-28 02:00
Existing antimicrobial resistance may become increasingly prevalent on its own -- with no interference from antibiotics -- in compact bacterial communities known as biofilms, or when protozo… Read More
2018-11-27 12:00
Pharmig’s latest publication is a guide to bacterial identification. The guide discusses why identification is important and what needs to be identified, answering the often-challengin… Read More
2018-11-26 01:30
FDA commissioner Scott Gottlieb recently unveiled a 2019 Strategic Approach for Combatting AMR (antimicrobial resistance) at a meeting September 14, 2018 organized by Pew. Pharmaceutical Exe… Read More
2018-11-25 14:00
FDA has issued new draft guidance: “Use of Liquids and/or Soft Foods as Vehicles for DrugAdministration: General Considerations for Selection and In Vitro Methods for Product Quality A… Read More
2018-11-24 13:30
The EDQM has issued a set of recommendations for the development of cost-effective and sustainable Quality Management Systems (QMSs) in Blood Establishments (BEs) across Europe. The document… Read More
2018-11-23 14:00
The 9.7 supplement of European Pharmacopoeia is now available and will be applicable in 38 European countries as from 01 April 2019.This volume is included in the 2019 subscription (9.6, 9.7… Read More
2018-11-22 13:30
Scientists have used light patterns to control the swimming speed of bacteria and direct them to form different shapes, according to a new study in the journal eLife.Controlling bacteria in… Read More
2018-11-21 13:00
Researchers have provided new insight on the geographical origins and global spread of two classes of the hepatitis B virus (HBV), according to a study in eLife.The findings identify the HBV… Read More
2018-11-20 13:00
FDA has issued a new guidance document: “Elemental Impurities in Drug Products Guidance for Industry.” This guidance provides recommendations regarding the control of elemental i… Read More
2018-11-19 13:00
In the past three to five years, there have been a number of advances in single-use sterile, disposable technologies, which have helped to both reduce the risk of contamination and to stream… Read More
2018-11-18 13:02
Pharmigs 26th Annual Conference Programme Interactive 2018 Final (1) by Tim Sandle on ScribdPosted by Dr. Tim Sandle, Pharmaceutical MicrobiologyPharmaceutical Microbiology (c) Dr Tim Sandl… Read More
2018-11-18 13:00
Colds vary in their severity and for how long they last for. The reason is not solely down to the type of virus or the relative health of individuals. The bacterial population of the nose is… Read More
2018-11-17 20:13
Millions of people in Europe, North America and Australia will die from superbug infections unless countries prioritise fighting the growing threat posed by bacteria immune to most known dru… Read More
2018-11-16 13:30
The European Medicines Agency (EMA) has launched a new version of its corporate website (www.ema.europa.eu).The website has a number of new features to improve user experience, including:an… Read More
2018-11-15 13:00
An average of ten children per day died last month in the hospital in Magaria in southern Niger, an alarming mortality rate mostly due to malnutrition and malaria in children under five, sai… Read More
2018-11-14 12:30
Stop Foodborne Illness, the national advocacy organization that represents individuals and families in the fight against foodborne illness, issued a statement today applauding a new FDA poli… Read More
2018-11-13 13:50
What are the implications of the human microbiome?The human microbiome refers to the totality of microorganisms and their genetic interactions within a given niche. Our understanding of the… Read More
2018-11-11 13:47
Escherichia coli bacteriaLong before bacteria had to contend with antibiotic drugs, they had to survive extreme temperatures as Earth warmed and cooled over millennia. Could the adaptations… Read More
2018-11-10 12:30
Intestinal bacteria can create an electric current, according to a new study from Lund University in Sweden. The results are valuable for the development of drugs, but also for the productio… Read More
2018-11-09 14:00
BiofilmStiff microbial films often coat medical devices, household items and infrastructure such as the inside of water supply pipes, and can lead to dangerous infections. Researchers have d… Read More
2018-11-08 13:00
The collection of an estimated 100 trillion resident microorganisms of the human body, termed the human microbiome, contributes to the physiology of human health and disease including nutrit… Read More
2018-11-07 13:00
Scientists have discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers als… Read More
2018-11-06 13:30
Twenty laboratory mice are poised to play an important role in preparing humans to go to Mars. A Northwestern University-led study of the microbiome in space is one of five science investiga… Read More
2018-11-05 12:30
In addition to selecting the right culture media, the use of an appropriate neutraliser is important in relation to surface, and some personnel, monitoring. Neutralisers are required to over… Read More
2018-11-05 00:02
Advancements in technology have undoubtedly improved our daily lives, yet in healthcare they have failed us miserably. The medical field is riddled with technology that is more hindrance tha… Read More
2018-11-04 12:30
Reported cases of legionnaire’s disease have been on the increase in Europe for years. To prevent outbreaks, detection of the bacteria is key. rqmicro developed a fast, cultivation-ind… Read More
2018-11-03 12:30
ProtakScientific has announced that the UK's Medicines and Healthcare products Regulatory Agency (MHRA) has agreed to support the company in the formation of a focus group to discuss the use… Read More
2018-11-02 13:30
The imaging method called cryo-electron microscopy (cryo-EM) allows researchers to visualize the shapes of biological molecules with an unprecedented level of detail. Now a team led by resea… Read More
2018-11-01 14:00
Working with human pathogens or biohazards poses serious risks, not only for employees, but for the public and communities as well. Infectious agents such as microorganisms, viruses, recombi… Read More
2018-10-31 13:00
FDA has issued a new guidance document: “Dissolution Testing and Acceptance Criteria for Immediate-Release Solid Oral Dosage Form Drug Products Containing High Solubility Drug Substanc… Read More
2018-10-30 20:57
Join us and @IBMScience at our upcoming webinar where NIBSC experts will be discussing how control materials are relevant. Book now: https://t.co/GJKm6FqYdm pic.twitter.com/BNCozPkSfu—… Read More
2018-10-30 13:30
Our limited understanding of the molecular basis for compound entry into and efflux out of Gram-negative bacteria is now recognized as a key bottleneck for the rational discovery of novel an… Read More
2018-10-29 13:00
Chronic obstructive pulmonary disease (COPD) mainly includes three related respiratory diseases, namely chronic bronchitis, chronic asthma and pulmonary emphysema. In each of the aforementio… Read More
2018-10-28 13:30
One of the most pressing concerns on the planet is the issue of multi-drug resistance bacteria and the risk these organisms pose to human health. One of the ways to address this could stem f… Read More
2018-10-27 11:30
More than 300,000 new cases of Lyme disease, the most common tick-borne illness in the United States, are diagnosed each year. In a new interview with CMRubinWorld, Dr. Brian Fallon, Directo… Read More
2018-10-26 11:30
The change affects chapter 5.1.5 “Application of the F concepts to heat sterilisation – 50105”.This chapter has been revised in order to add a definition of FH for dry heat… Read More
2018-10-25 13:00
Two UH researchers have won a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases to develop technology that will quickly suggest the most promising… Read More
2018-10-24 13:00
A new eBook from Pharmaceutical Technology – ‘Strategies for Building a Flexible Clinical Supply Chain to Meet Modern Challenges’ Proactively planning for a supply chain is… Read More
2018-10-23 19:18
FDA has issued a new guidance document ‘Labeling for Biosimilar Products’.FDA - Labeling for Biosimilar Products. The goal of a biosimilar product development program is to demon… Read More
2018-10-22 18:51
Tim Sandle has written an editorial of the special edition of the Journal of GxP Compliance, dedicated to pharmaceutical microbiology. This special edition captures some of the current theme… Read More
2018-10-21 12:30
A new technique for manipulating small cell structures for use in a range of biotechnical applications including the production of biofuels and vaccines has been developed by a team of scien… Read More
2018-10-20 11:00
A new diagnostic tool has been developed by researchers at The University of Texas at Austin that can easily, quickly and cheaply identify whether a mosquito belongs to the species that carr… Read More
2018-10-19 12:30
Researchers from North Carolina State University have synthesized an analog of lipoxazolidinone A, a small molecule that is effective against drug-resistant bacteria such as MRSA. This molec… Read More
2018-10-18 12:30
Annex 2 to EU GMP has recently been updated. This is: “Annex 2 Manufacture of Biological active substances and Medicinal Products for Human Use.” This came into effect on 26th Ju… Read More
2018-10-17 12:30
TB Alliance has initiated a pivotal clinical trial, SimpliciTB (pronounced: sim-plis-i-tee-bee), that will evaluate whether a new four-drug regimen can treat most types of tuberculosis (TB)… Read More
2018-10-16 12:30
Antimicrobial resistance is a global public health challenge. Antimicrobial drugs have been widely used in human and veterinary medicine for more than 60 years. When used judiciously, antimi… Read More
Use Of Hazard Analysis And Critical Control Points (HACCP) - Part 1: Assessing Microbiological Risks
2018-10-15 19:08
Environmental monitoring is an important part of a biocontamination control strategy in a pharmaceutical or healthcare organization. Monitoring is undertaken in order to assess if controlled… Read More
2018-10-14 15:13
As the Ebola outbreak in the northeast of the Democratic Republic of Congo (DRC) continues to spread, the international medical humanitarian organization Doctors Without Borders/Médec… Read More
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