2020-02-13 12:30
A bacterial pathogen that causes strep throat and other illnesses cloaks itself in fragments of red blood cells to evade detection by the host immune system, according to a new study. The re… Read More
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pharmaceutical microbiology,quality assurance, healthcare, cleanroom, contamination control, microbiology, tim sandle, sterility, disinfection
2020-02-12 12:30
Microbes can be engineered to produce a variety of useful compounds, including plastics, biofuels, and pharmaceuticals. However, in many cases, these products compete with the metabolic path… Read More
2020-02-11 12:30
In this age of "big data," artificial intelligence (AI) has become a valuable ally for scientists. Machine learning algorithms, for instance, are helping biologists make sense of the dizzyin… Read More
2020-02-10 13:00
Following the death of one patient and another falling seriously ill (reported in June 2019), the U.S. Food and Drug Administration (FDA) has called for greater controls over fecal transplan… Read More
2020-02-09 13:00
Malaria affects more than 200 million people worldwide every year, and resistance to antimalarial treatments is constantly increasing. This infectious disease is caused by Plasmodium parasit… Read More
2020-02-08 13:00
Bacterial exposure has been identified as a potential environmental risk factor in developing celiac disease, a hereditary autoimmune-like condition that affects about one in 70 Australians… Read More
2020-02-07 13:00
Scientists from Trinity College Dublin have discovered that two very different species of bacteria have evolved distinct, powerful antibiotic arsenals for use in the war against their bacter… Read More
2020-02-06 13:00
Using a genomics strain-tracking bioinformatics tool, researchers investigated whether shared bacterial strains remain stable and resilient to changes in diet or environment after adult twin… Read More
2020-02-05 12:00
There’s been a lot of talk in recent years about the gut’s microbiome. Probiotics and prebiotics have become the buzzwords of the day.A guest post by Indiana Lee.Talk of intestin… Read More
2020-02-04 13:00
While it is well known within the medical community that there is a link between the bacteria Helicobacter pylori (H. pylori) and rates of gastric cancer -- commonly referred to as stomach c… Read More
2020-02-03 13:00
Microbial biofilms - structured consortium of bacteria that are embedded in layers of self-produced polymer matrices, largely composed of polysaccharide, protein and DNA – are well des… Read More
2020-02-02 11:30
Layering minute amounts of Manuka honey between layers of surgical mesh acts as a natural antibiotic that could prevent infection following an operation, new research has shown.Meshes are us… Read More
2020-02-01 13:18
These days, people of all types and from all backgrounds are more concerned about their health than ever - and they're increasingly turning to modern technology to help get the assistance th… Read More
2020-02-01 12:30
The fight against antimicrobial resistance has a new problem – raw pet food, according to new research. Sales of biologically appropriate raw food, especially for dogs, have risen in r… Read More
2020-01-31 11:00
Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacter… Read More
2020-01-30 12:00
The microbial community populating the human body plays an important role in health and disease, but with few exceptions, how individual microbial species affect health and disease states re… Read More
2020-01-29 13:30
Taking advantage of powerful advances in CRISPR gene editing, scientists at the University of California San Diego have set their sights on one of society's most formidable threats to human… Read More
2020-01-28 13:30
Macrophages have two faces: In healthy tissue, they perform important tasks and support their environment. However during an infection, they stop this work and hunt down the pathogens instea… Read More
2020-01-27 12:30
Good Distribution Practice (GDP) concerns the distribution processes for pharmaceutical products that results in medics and patients obtaining access to the medications required. For the pha… Read More
2020-01-26 13:30
Researchers at Baylor College of Medicine report evidence that refutes the link between increased levels of herpes virus and Alzheimer's disease. In addition, the researchers provide a new s… Read More
2020-01-25 13:00
A new computational model suggests that the food web of the human gut microbiome follows a hierarchical structure similar to that of larger-scale ecosystems. In the human gut, hundreds of sp… Read More
2020-01-24 13:00
A new bacterial identification method, called ON-rep-seq, examines selective, strain-specific fragments of the bacterial genome, allowing the generation of results that earlier required DNA… Read More
2020-01-23 10:00
Columbia scientists have captured the first images of a new gene editing tool that could improve upon existing CRISPR-based tools. The team developed the tool, called INTEGRATE, after discov… Read More
2020-01-22 13:01
At the request of the European Commission, the European Medicines EMA triggered a review of ranitidine medicines after tests showed that some of these products contained an impurity called N… Read More
2020-01-21 11:00
Microbiologists have found that many washing machines in hospital setting as are reservoirs of multidrug-resistant bacteria. In one case study pathogens, were transmitted regularly to newbor… Read More
2020-01-20 12:00
With biological tests all measurements susceptible to variations in analytical conditions should be suitably controlled as far as is practicable. Here the LAL assay has a relatively elevated… Read More
2020-01-19 11:30
Methicillin-resistant Staphylococcus aureus (MRSA) causes hospital- and community-acquired infections. It is not clear whether genetic characteristics of the bacteria contribute to disease p… Read More
2020-01-18 13:00
AMR is now considered a key threat to global health, leading to more mortality and increased healthcare costs threatening future conduct of routine medical procedures. Traditional approaches… Read More
2020-01-17 13:30
New research published today in the journal Parasitology shows how the prehistoric inhabitants of a settlement in the freshwater marshes of eastern England were infected by intestinal worms… Read More
2020-01-16 12:00
A new Veterinary Medicines Regulation (Regulation (EU) 2019/6) has been introduced to modernise the existing rules on the authorisation and use of veterinary medicines in the European Union… Read More
2020-01-15 12:00
The U.S. Food and Drug Administration (FDA) is providing information on recent actions responding to ongoing concerns about ethylene oxide in commercial operations and encouraging innovative… Read More
2020-01-14 20:12
Irrespective of all the research that has been going on throughout the years, there is a lot of important information that is not known regarding the human brain. Numerous mental diseases, a… Read More
2020-01-14 11:00
Aufit book 2.pdf by Tim Sandle on ScribdPosted by Dr. Tim Sandle, Pharmaceutical MicrobiologyPharmaceutical Microbiology (c) Dr Tim Sandle
http://www.pharmamicroresources.com Read More
2020-01-12 12:00
An international research collaboration has discovered a new bacteria-killing toxin that shows promise of impacting superbug infectious diseases.The discovery of this growth-inhibiting toxin… Read More
2020-01-11 11:30
Biology encodes information in DNA and RNA, which are complex molecules finely tuned to their functions. But are they the only way to store hereditary molecular information? Some scientists… Read More
2020-01-10 11:00
Researchers at McGill University's Faculty of Medicine have made important strides in understanding the functioning of enzymes that play an integral role in the production of antibiotics and… Read More
2020-01-09 09:30
A new study has found that microorganisms living in the gut may alter the ageing process, which could lead to the development of food-based treatment to slow it down.All living organisms, in… Read More
2020-01-08 11:00
A new study has found that crows living in large social groups are healthier than crows that have fewer social interactions.The research, led by Dr Claudia Wascher of Anglia Ruskin Universit… Read More
2020-01-07 11:30
FDA has released draft guidance for industry (GFI) #263 to explain the recommended process for voluntarily bringing remaining approved animal drugs containing antimicrobials of human medical… Read More
2020-01-06 13:00
The concept of Hazard Analysis and Critical Control Points (HACCP) methodology is a system that enables the production of safe products, be they pharmaceuticals or health care products and d… Read More
2020-01-06 12:30
Researchers at the Biozentrum of the University have demonstrated how bacteria coordinate cell division with the replication of their genetic material. In an interdisciplinary study they exp… Read More
2020-01-05 12:00
2020 is a defining year for the next, bolder phase of efforts to combat NTDs. Dr. Mwele Malecela, WHO NTD Director states: “I was asked to speak today about WHO’s vision post-202… Read More
2020-01-04 11:30
New research has identified a new mechanism that plays a role in controlling how the herpes virus alternates between dormant and active stages of infection.The herpes virus causes cold sores… Read More
2020-01-03 13:30
With insecticide resistance eroding the life-saving power of bed nets—a major malaria-fighting tool—researchers reported today that in a clinical trial that involved distributing… Read More
2020-01-02 13:00
A draft revision of the PIC/S GMP Guide Annex 2 (Manufacture of biological medicinal substances and products for human use) has been prepared by the PIC/S Working Group on revision of Annex… Read More
2019-12-31 12:30
The Stop TB Partnership today launched the Global Plan to End TB 2018-2022, which calls for 2.6 billion USD per year for vital research and development of new tuberculosis (TB) diagnostic to… Read More
2019-12-29 12:30
New legislation requiring pharmaceutical companies to implement 'serialization' is now coming into force. This means that no counterfeit product should enter the supply chain and no legitima… Read More
2019-12-28 16:48
Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (http://www.pharmamicroresources.com/)Pharmaceutical Microbiology (c) Dr Tim Sandle
http://www.pharmamicroresources.com Read More
2019-12-28 13:00
The evolution of dietary and hygienic habits in Western countries is associated with a decrease in the bacteria that help in digestion. These very bacteria were also found in the Iceman, who… Read More
2019-12-27 13:00
EMA’s human medicines committee (CHMP) is requesting as a matter of precaution that marketing authorisation holders for human medicines containing chemically synthesised active substan… Read More
2019-12-26 13:30
Resistance to two critical antibiotic types, one a "drug of last resort" when all others fail against some "superbugs," are widely distributed in Southeast Asia, raising the risk of untreata… Read More
2019-12-25 12:30
Medical microbiologists have established how the bacterium Escherichia coli knows how to cause the worst possible infection. The new insight should assist with preventing the foodborne illne… Read More
2019-12-23 12:00
ISO 22301, Security and resilience – Business continuity management systems – Requirements, is the world’s first International Standard for implementing and maintaining an… Read More
2019-12-22 12:00
Amid a global surge of infections with dengue and fears climate change will make it worse, an international alliance of researchers presented new evidence today showing reports that the dise… Read More
2019-12-21 11:00
The European Medicines Agency (EMA) has asked the human medicines committee (CHMP) to provide guidance on avoiding the presence of certain carcinogenic ingredients in drugs, after nitrosamin… Read More
2019-12-20 13:00
The FDA has announced the approval of Jynneos Smallpox and Monkeypox Vaccine, Live, NonReplicating, for the prevention of smallpox and monkeypox disease in adults 18 years of age and older d… Read More
2019-12-19 13:00
In 2019 the FDA announced it had received comments and feedback from wholesale distributors expressing concern with industrywide readiness for implementation of the verification of saleable… Read More
2019-12-18 12:00
The pharmaceutical industry has an enormous amount of influence and enjoys spectacular profits year after year. When it comes to maintaining a successful pharmaceutical lab, however, all thi… Read More
2019-12-17 12:00
A new document of interest has been issued relating to change controls:“Draft PIC/S Recommendation on How to Evaluate / Demonstrate the Effectiveness of a Pharmaceutical Quality System… Read More
2019-12-16 12:00
Unidirectional airflow devices and microbiological safety cabinets are a common feature in many laboratories, including applications to achieve contamination control. Such devices are suitab… Read More
2019-12-15 12:30
Researchers have provided new insight into a mechanism behind the evolution of antibiotic resistance in a type of bacterium that causes severe infections in humans.Their findings in the mult… Read More
2019-12-14 12:00
A new study titled “Automated Detection of Streptococcus pyogenes pharyngitis using COLOREX Strep A CHROMagar and WASPLab™ Artificial Intelligence Chromogenic Detection Module So… Read More
2019-12-13 11:30
A new volume-based agreement announced today by Unitaid, the Global Fund and Sanofi will drastically lower the price of rifapentine (Priftin®), a critically important drug used to preven… Read More
2019-12-12 12:00
Cigarette smoke can make MRSA bacterial strains more resistant to antibiotics, new research from the University of Bath has shown. In addition cigarette smoke exposure can make some strains… Read More
2019-12-11 13:00
IGeneX Laboratory Publishes Results of Novel Line Immunoblot Testing for Tick-borne Relapsing FeverA novel test for a new form of Lyme disease was described in a report published in the pres… Read More
2019-12-10 13:00
The U.S. Food and Drug Administration released draft guidance for industry (GFI) #263 to explain the recommended process for voluntarily bringing remaining approved animal drugs containing a… Read More
2019-12-09 12:00
American Pharmaceutical Review has run another in its Microbiology Roundtable features. Here is an extract from Tim Sandle:Q. In general, what are some of the current critical issues/trends… Read More
2019-12-08 13:00
Using genetic sequencing, University of California San Diego School of Medicine researchers have identified a principal cellular player controlling HIV reproduction in immune cells which, wh… Read More
2019-12-07 12:30
Trillions of microbes in the intestine aid human health, including digestion of breast milk, breaking down fiber and helping control the immune system. However, antibiotic treatment is known… Read More
2019-12-06 12:30
It is estimated that influenza (flu) results in 31.4 million outpatient visits each year. New research from the University of Minnesota Medical School provides insights into how the body can… Read More
2019-12-04 12:00
A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment -- like a fisherman pulling up a catch from th… Read More
2019-12-03 12:00
French investigators have described development of resistance to one of the last resort therapies used to treat extremely drug-resistant Pseudomonas aeruginosa. That resistance arose in a si… Read More
2019-12-02 14:00
Each final container of all parenteral preparations shall be inspected to the extent possible for the presence of observable foreign and particulate matter.In relation to this a new article… Read More
2019-12-01 12:00
Today marks an anniversary of sorts. This website - Pharmaceutical Microbiology Resources - is ten years old, and with over 3 million reads.I began blogging and posting interesting research… Read More
2019-11-30 12:00
Trillions of microbes in the intestine aid human health, including digestion of breast milk, breaking down fiber and helping control the immune system. However, antibiotic treatment is known… Read More
2019-11-29 12:30
Swapping a single amino acid in a simple bacterial protein changes its structure and function, revealing the effects of complex gene evolution, finds a new study published in the journal eLi… Read More
2019-11-28 21:55
The maturation of skin microbial communities during childhood is important for the skin health of children and development of the immune system into adulthood, but only a few studies have an… Read More
2019-11-27 11:00
The Sun can indeed shine out of your backside, suggests research. Not because you’re self-absorbed, but because you’ve absorbed gut-altering UV radiation.This is the first study… Read More
2019-11-26 20:54
Scientists have uncovered a novel antibiotic-free approach that could help prevent and treat one of the most widespread bacterial pathogens, using nanocapsules made of natural ingredients.He… Read More
2019-11-25 12:30
A blockchain is a time-stamped series of immutable record of data that is managed by a cluster of computers not owned by any single entity (this means it is ‘decentralized’). Eac… Read More
2019-11-24 13:30
Scientists have found a new species of choanoflagellate. This close relative of animals forms sheets of cells that 'flip' inside-out in response to light, alternating between a cup-shaped fe… Read More
2019-11-23 13:00
A draft document has been issued to a limited audience following the decision of the WHO Expert Committee on Biological Standardization (ECBS), it is proposed to omit chapter 3.7, “Und… Read More
2019-11-22 13:00
The new Veterinary Medicines Regulation (Regulation (EU) 2019/6) will modernise the existing rules on the authorisation and use of veterinary medicines in the European Union (EU) when it bec… Read More
2019-11-21 12:30
A new ISO standard has been issued, on the subject of risk assessment methods. IEC 31010, Risk management — Risk assessment techniques, features a range of techniques to identify and u… Read More
2019-11-20 12:00
A Nature Review has been issued, covering the gut microbiota’s role in colorectal cancer.According to new experimental evidence from Jun Yu’s group at The University of Hong Kong… Read More
2019-11-19 13:00
Medical science has come a long way since the days of leeches and trepanning, but new technologies are emerging every day that will change the way we look at pharmaceutical science. Here are… Read More
2019-11-18 12:00
Cleanrooms remain a central focus of regulatory inspections and it is good practice for those working within pharmaceuticals and healthcare to assess regulatory trends. This task is difficul… Read More
2019-11-17 11:30
Tim Sandle has taken part in a podcast with the Institute of Validation Technology as part of their ‘Voices In Validation’ series. Stacey Bruzzese talks to Dr. Tim Sandle, the He… Read More
2019-11-16 14:00
When viewed with specialized microscopes, microbial cells show an individual fluorescence pattern, or signature, that depends on the mixture of biomolecules contained within the cells. That… Read More
2019-11-15 12:30
With climate change comes increasing water shortages, and potentially longer periods of drought. As policymakers look urgently to wastewater recycling to stem the gap in water resources, the… Read More
2019-11-14 22:27
Here is my article on digital transformation of pharmaceuticals - "Becoming Pharma 4.0: How Digital Transformation Is Reshaping Pharmaceuticals".The digital transformation of biopharmaceutic… Read More
2019-11-14 12:30
Researchers at Western University have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack… Read More
2019-11-12 12:00
Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité -- Universitätsmedizin Berlin have discovered a ne… Read More
2019-11-11 12:00
The concept of quality is central to the delivery of laboratory services and this is achieved through the incorporation of quality systems, quality control and quality assurance in all aspec… Read More
2019-11-10 13:00
Antibiotics are still the most important weapon for combatting bacterial infections. But medical science is running out of "ammunition" because of more and more frequently occurring resistan… Read More
2019-11-09 12:00
Researchers have captured images of the formation of individual viruses, offering a real-time view into the kinetics of viral assembly. The research provides new insights into how to fight v… Read More
2019-11-08 12:00
A 5-minute soak in a 40% solution of household bleach decontaminated stainless steel wires coated with chronic wasting disease (CWD) prions, according to a new study by National Institutes o… Read More
2019-11-07 12:30
An emerging, novel approach to control antibiotic-resistant bacterial infections is based on the use of light, in particular of blue wavelengths (400–470 nm). A new researc… Read More
2019-11-06 12:30
Two European disinfectant test standards have been updated this year.EN 1276: 2019 Phase 2 / Step 1 – Quantitative Bactericidal Suspension Test This involves at least two Gram-positive… Read More
2019-11-05 11:00
The US Environmental Protection Agency will phase out animal testing of chemical products by 2035, in favour of computer-based and in vitro tissue models. As part of efforts to “aggres… Read More
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