2024-04-01 09:08
Respiratory syncytial virus was isolated from the cold-like respiratory tract of chimpanzees in 1956. It is called respiratory syncytial virus because it causes the fusion of adjacent cells… Read More
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2024-04-01 09:01
Snake bites seriously threaten public health security in tropical and subtropical countries and regions. Due to the high mortality and disability rates caused by venomous snake bites, there… Read More
2024-03-01 02:54
Procalcitonin (PCT) is the propeptide of calcitonin. The production of procalcitonin during infection and sepsis does not depend on calcitonin levels, but is closely related to the release o… Read More
2024-03-01 02:14
GLP-2 (glucagon-likepeptide-2) was discovered and named by the Lilly Laboratory in the United States when cloning the proglucagon gene (PG). In 1996, Drucker et al. discovered that the activ… Read More
2024-01-31 07:53
Genetically engineered drugs are introduced into host cells such as Escherichia coli, yeast or mammalian cells through recombinant technology to construct engineering strains or cell strains… Read More
2024-01-31 07:38
The incidence and prevalence of diabetes are increasing year by year globally, and patients with diabetes are at increased risk of cardiovascular disease and heart failure. Diabetic cardiomy… Read More
2023-12-29 06:20
Herpes simplex virus (HSV) belongs to the herpesvirus alpha subfamily and has a unique 4-layer structure. The core of HSV is a linear double-stranded DNA of about 152 000 bp, surrounded by a… Read More
2023-12-29 06:13
Alzheimer’s disease (AD) is a progressive neurodegenerative disease with an insidious onset. Clinically, it is characterized by comprehensive dementia manifestations such as memory imp… Read More
2023-11-27 09:35
As a tumor suppressor, p53 is one of the most commonly mutated genes in human cancers. Due to its important role in tumor suppression, p53 has attracted great interest from researchers in dr… Read More
2023-11-27 09:29
The tumor microenvironment is composed of tumor cells and non-tumor cells (including fibroblasts, vascular and lymphatic endothelial cells, various immune cells) and extracellular components… Read More
2023-10-30 02:33
Staphylococcus aureus (S. aureus) is an important class of food-borne pathogens that cause food contamination and food poisoning, and is also a symbiont of human skin and mucous membranes. S… Read More
2023-10-30 02:21
Streptococcus pneumoniae is a class of Gram-positive pathogenic bacteria that was first isolated in 1881. The chemical composition of the mucus layer on the surface of Streptococcus pneumoni… Read More
2023-10-05 06:34
Type 1 diabetes (T1DM) is an autoimmune disease caused by the destruction of beta cells first, leading to the destruction of related pancreatic islet function. In patients with this disease… Read More
2023-10-05 06:29
Type 1 diabetes (T1DM) is an autoimmune disease caused by the destruction of beta cells, leading to the destruction of related pancreatic islet functions. In patients with this disease, both… Read More
2023-09-01 05:59
Gangliosides (GA) are a class of glycosphingolipids (GSLs) containing sialic acid, which are widely distributed in tissues and body fluids, and are most abundant in the nervous system, where… Read More
2023-09-01 05:52
Tripartite-motif Protein Family (TRIM)
TRIM is composed of more than 80 proteins with E3 ubiquitin ligase activity. According to the different structures of TRIM proteins, they are divide… Read More
2023-08-01 06:05
Aspartame is an artificial dipeptide sweetener, which is synthesized from L-phenylalanine and aspartic acid, and its scientific name is L-aspartic acid-L-phenylalanine methyl ester. It is a… Read More
2023-08-01 05:56
Hepatocellular cancer (HCC) is a clinically common malignant tumor of the digestive tract, which is seriously harmful to human health, and according to the survey, liver cancer accounts for… Read More
2023-07-03 07:20
Since Dutch researchers discovered human metapneumovirus (hMPV) in 2001, hMPV and its subtypes have been detected in many countries. hMPV is a respiratory pathogenic virus, which belongs to… Read More
2023-07-03 07:12
Respiratory tract infection is an important cause of human morbidity and death worldwide and one of the main causes of death in children under 5 years old. Since 2001, researchers in the Net… Read More
2023-06-01 02:18
Inflammation is a series of complex response events produced by the host system to pathogen infection and various tissue injuries. When the inflammatory response continues, it enters the sta… Read More
2023-06-01 02:11
In recent years, with the changes in human environment and diseases, the incidence of fungal infections has been increasing year by year. Candida albicans is one of the important pathogens c… Read More
2023-05-04 02:57
After the host is infected by the virus, the immune system can generate a corresponding immune response. Antibodies specific to viral surface proteins produced at this time can often prevent… Read More
2023-05-04 02:44
AMOT family, also known as the Motin family, has three members: angiomotin (AMOT), angiomotin-like protein 1 (AMOTL1), and angiomotin-like protein 2 (AMOTL2). There are two shear isomers of… Read More
2023-04-20 08:37
Antibody, also called Immunoglobulin, is a large Y globulin secreted by Effector B cell which is used in identifying and neutralizing the outsiders like bacterial and virus. Antibody is only… Read More
2023-04-01 05:44
Influenza A viruses, the culprits of respiratory illness in humans, are a complex and multifaceted group of viruses. Among the numerous subtypes of Influenza A, H1N1 and H3N2 with a notoriou… Read More
2023-04-01 05:44
Inflammation is an important defense response of the body that can control and clear various endogenous or exogenous damaging factors acting on the body, and also has a role in repairing dam… Read More
2023-03-01 08:55
Transglutaminase (TGase) is an enzyme that catalyzes the acyl transfer reaction. It uses the C-carboxamide group of the glutamine residue in the peptide bond as the acyl donor, and the E-ami… Read More
2023-03-01 08:36
Biopharmaceutical impurities can be divided into two categories: extraneous contaminants and product-related impurities. Extraneous contaminants include microbial contamination, pyrogens, ce… Read More
2023-02-02 06:18
Feline herpesvirus type 1 (FHV-1) can cause acute and highly contagious infectious diseases in cats, namely feline infectious rhinotracheitis. In 1958, FHV-1 was isolated and identified for… Read More
2023-02-02 06:06
Introduction
Malaria is caused by infection with Plasmodium parasites. Plasmodium belongs to unicellular eukaryote, and the Plasmodium that infects human body mainly comprises 5 kinds: Plasm… Read More
2022-12-30 06:41
Mesothelin is a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein. Its biological function has not yet been clarified, but due to its limited distribution in normal tissu… Read More
2022-12-30 06:24
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by bilateral motor (eg, bradykinesia, resting tremor, postural instability, rigidity) and nonmotor (e… Read More
2022-12-01 07:41
Since the discovery of cowpox inoculation to prevent smallpox in the 18th century, vaccines have become an important means for human beings to resist pathogen infection and prevent the occur… Read More
2022-12-01 07:30
Porcine pseudorabies (PR) is an acute infectious disease of pigs caused by porcine pseudorabies virus (PRV). PRV belongs to the herpesviridae family, the alphaherpesviridae subfamily, and th… Read More
2022-10-31 09:21
According to data from the European Food Safety Authority, the European Centre for Disease Prevention and Control and the EU Avian Influenza Reference Laboratory, large-scale bird flu has oc… Read More
2022-10-31 09:09
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) belongs to the Arteriviridae family and belongs to the Arterivirus. PRRSV can be divided into type I (PRRSV type I) and type… Read More
2022-09-30 08:27
Brucellosis is a zoonotic infectious disease caused by Brucella, and it is one of the most widespread zoonotic diseases in the world, which brings great losses to the animal husbandry indust… Read More
2022-09-30 07:42
African swine fever (ASF) is a contagious infectious disease caused by African swine fever virus (ASFV) that spreads only among domestic pigs and wild boars, with a rapid onset, short course… Read More
2022-09-16 05:53
Brucellosis is caused by the Brucella. The bacterium is a gram-negative coccus that can parasitize in cells, infect livestock, cause abortion and infertility, and infect humans and cause con… Read More
2022-09-16 05:46
Marburg virus, named after the former West German city of Marburg, also known as green monkey disease virus, green monkey factor, and Marburg virus, etc., is a deadly virus and the pathogeni… Read More
2022-08-02 05:01
Legionnaires’ disease (LD) first broke out on a large scale at a military rally in Philadelphia in 1976, killing 34 people. Since then, there have been outbreaks or sporadic transmissi… Read More
2022-08-02 03:54
Measles virus (MV) is the causative agent of measles in children. Measles is a highly contagious infectious disease. According to the World Health Organization, about 20 million children wor… Read More
2022-07-01 03:58
The complement system is considered to be a biological effector system composed of a group of thermolabile enzymatically active globulins on the surface of serum, tissue fluid and cell membr… Read More
2022-07-01 03:49
Legionella is a class of aerobic Gram-negative bacilli, widely distributed in natural fresh water, artificial water supply systems (such as bathers, fountains, cooling water towers), air con… Read More
2022-06-02 07:55
Monkeypox is caused by the monkeypox virus. Monkeypox virus is a virus belonging to the genus Orthopoxvirus of the Poxviridae family. Monkeypox virus has the typical shape of Orthopox virus… Read More
2022-06-01 08:02
Epstein-Barr virus (EBV) is a kind of γ-herpes virus that is infected with human beings. In 1964, the Epstein team found in Burkittlymphoma (BL) that it consists of a double-chain DNA… Read More
2022-06-01 07:55
Epstein-Barr Virus (EBV) is a large enveloped virus of double-stranded DNA among the eight known herpesviruses. After EBV infection of cells, it accumulates in the nucleus, and there are two… Read More
2022-04-29 09:00
Strongyloides is an opportunistic pathogenic parasitic nematode. Adults parasitize in the small intestine of cats, dogs and humans. The larvae can invade lung, brain, liver, kidney and other… Read More
2022-04-29 08:54
Staphylococcus aureus (S. aureus) is an important food-borne pathogen that causes food contamination and food poisoning. It is also a symbiont of human skin and mucous membranes. About 20% t… Read More
2022-04-29 08:47
SEB poisoning can cause a series of toxic reactions and even toxic shock syndrome, with clinical manifestations of high fever, hypotension, rash, weight loss, multiple organ failure and even… Read More
2022-04-01 05:12
Over the past few decades, there have been multiple outbreaks of viruses causing severe and severe disease around the world, including known and unknown viral pathogens such as SARS-CoV, Ebo… Read More
2022-04-01 03:37
Nipah virus (NiV) is a zoonotic virus newly discovered in recent years, which mainly causes damage to the nervous system and respiratory system of humans and pigs. People began to think that… Read More
2022-02-28 08:13
Although natural hirudin is in great demand in clinical and pharmaceutical research, it is not easy to obtain. With the gradual exhaustion of natural leech resources, the gap between supply… Read More
2022-02-28 08:06
Hirudin is one of the most significant and most studied active ingredients in leeches and their salivary glands. It is a small molecule protein (polypeptide). Leeches are rich in hirudin, wh… Read More
2022-01-28 08:47
Since the beginning of the epidemic, the new coronavirus (SAR-CoV-2), the pathogen of COVID-19, has continuously evolved and mutated, producing mutant strains with enhanced transmission and… Read More
2022-01-28 08:36
Helicobacter pylori (Hp) spread from East Africa about 58,000 years ago and then developed into different pathogenic strains. Relevant studies have shown that 80% of gastric ulcers and 90% o… Read More
2022-01-28 08:32
Helicobacter pylori (HP) infection is the most common chronic infectious disease in the world, affecting approximately 4.4 billion people worldwide, but the prevalence varies greatly. HP can… Read More
2021-12-28 05:22
Obesity refers to a certain degree of obvious overweight and thick fat layer, which is a state caused by excessive accumulation of body fat, especially triglycerides. Excessive food in… Read More
2021-12-28 05:09
Food allergy (food hypersensitivity) is an abnormal reaction of the body’s immune system caused by food. More precisely, it is an allergic reaction caused by allergens in food.
Fo… Read More
2021-12-28 03:57
The in vitro method uses in vitro detection methods to evaluate the potential sensitization of food allergens, which is safer and more feasible than in vivo experimental detection. In c… Read More
2021-11-30 09:20
As mentioned earlier, vitamin D can regulate the entire process of tumorigenesis, including not only the initial stage of the tumor, but also the development stage of the tumor. Since the in… Read More
2021-11-30 09:08
Vitamin D is a fat-soluble vitamin that can be obtained from food. At the same time, cholesterol in the body can be oxidized to 7-deoxycholesterol, which is converted into vitamin D by ultra… Read More
2021-11-01 06:17
In 2010, Patapoutian of the Scripps Institute and his colleagues discovered proteins that act as two switches—proteins called Piezo1 and Piezo2 (a mechanically sensitive ion channel)… Read More
2021-11-01 06:06
On October 4, 2021, the Nobel Prize Conference held at the Caroline Medical School in Sweden announced that the 2021 Nobel Prize in Physiology and Medicine will be awarded to David Julius an… Read More
2021-10-11 02:10
Impurities derived from cell culture include but are not limited to inducers, antibiotics, serum and other media components. These impurities need to be tested and evaluated one by one using… Read More
2021-10-11 01:44
The chemical structure of polyethylene glycol (PEG) is HO-(CH2CH2)n-OH, which is a general term for ethylene glycol polymers with a relative molecular mass of 200 to 8000 and above.
Polyethy… Read More
2021-09-01 06:57
The development of agricultural industrialization makes the production of agricultural products increasingly dependent on foreign substances such as pesticides, antibiotics and hormones.&nbs&hell…Read More
2021-09-01 06:53
One of the characteristics that cancer cells can obtain and maintain in the body is their ability to evade detection and destruction by the human immune system. For example, some tumor… Read More
2021-08-06 06:37
The COVID-19 outbreak has been out for more than a year. Except for the D614G variant, which was detected early, increased its transmission capacity and quickly occupied the world, the curre… Read More
2021-08-06 06:31
In the past few decades, monoclonal drugs have had huge applications in diagnosis, treatment and drug targeting. The diagnosis of any infectious disease usually requires proof of the pa… Read More
2021-07-01 05:57
In recent years, the overall incidence of global malignant tumors has shown a continuous upward trend. At present, the main clinical treatment of malignant tumors is surgery, chemothera… Read More
2021-07-01 05:49
Membranous nephropathy (MN) was first described in 1959. In 1959, Heymann et al. first established the classic MN rat model-Heymann nephritis model. And then, they found that the pathogenesi… Read More
2021-05-31 07:27
Antibodies are biological protein molecules that are produced by immune B cells after being stimulated by antigens that can specifically bind to the antigen, and then neutralize the antigen… Read More
2021-05-31 07:21
The early stages of apoptosis signal transduction involve a complex cascade of signal molecules. Among them, early apoptosis signal transduction focuses on the activation of signal tran… Read More
2021-04-28 03:50
In chemistry, biochemistry, and pharmacology, the dissociation constant (KD) is a specific type of equilibrium constant used to measure the tendency of larger objects to reversibly separate… Read More
2021-04-28 03:36
Immunohistochemistry is to apply the basic principle of immunology antigen-antibody reaction, that is, the principle of the specific binding of antigen and antibody. Through a chemical react… Read More
2021-04-01 01:21
Immunohistochemistry technology has become an indispensable and important method in the routine work and scientific research of the pathology laboratory. It is widely used in clinical p… Read More
2021-03-31 08:57
The structure of all immunoglobulins is basically the same, consisting of two heavy chains (Heavy, abbreviated as H) and two light chains (Light, abbreviated as L), and looks like a “Y… Read More
2021-03-01 06:08
Oxidative stress is the oxidative modification of biological components in the body, such as proteins, nucleic acids and lipids. Since these biological substances are an important part of th… Read More
2021-03-01 05:56
In 1971, Engvall and Perlmann published an enzyme-linked immunosorbent assay (ELISA) for the quantitative determination of IgG, which made the enzyme-labeled antibody technology used for ant… Read More
2021-01-23 07:18
Caspases are a recently discovered group exists in the cytosol structurally related cysteine protease, which is an important common active site contains a cysteine. And it specifically… Read More
2021-01-23 07:15
Apoptosis refers to the physiological process of autonomous and orderly death of cells controlled by genes in order to maintain a stable environment in the body.
Cell death in the body can o… Read More
2020-12-28 06:59
As we all know, tumor tissue is not only composed of cancer cells, it also contains other types of cells. These other cell types can affect tumor behavior and have a profound impact on… Read More
2020-12-28 06:54
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) appeared at the end of 2019, and the sequencing was completed in January 2020. Although the source of transmission is still… Read More
2020-11-24 07:59
The 2019 Coronavirus Disease (COVID-19) caused by the new coronavirus SARS-CoV-2 is now raging around the world. Existing studies have shown that SARS-CoV-2 infects host cells through the re… Read More
2020-11-24 07:55
Immune cell infiltration of solid tumors is one of the hallmarks of cancer and plays a vital role in disease progression. Through the recognition of the important role of immune cells i… Read More
2020-11-24 07:55
Immune cell infiltration of solid tumors is one of the hallmarks of cancer and plays a vital role in disease progression. Through the recognition of the important role of immune cells i… Read More
2020-10-20 08:08
The new coronavirus SARS-CoV-2 causes the 2019 Coronavirus Disease (COVID-19) and is now raging around the world. There is currently no US Food and Drug Administration (FDA) approved method… Read More
2020-10-20 08:06
On October 7, 2020, the Royal Swedish Academy of Sciences has decided to award the 2020 Nobel Prize in Chemistry to Dr. Emmanuelle Charpentier of the Max Planck Institute for Pathogenesis in… Read More
2020-09-23 02:49
As we age, the body will accumulate “garbage” in the body during the process of converting food into energy. Clinical statistics have found that the risk of cancer and related mo… Read More
2020-09-23 02:46
It has been clinically found that polyamine biosynthesis is often dysregulated in human cancers, especially in the development of early colorectal cancer. Recent research on polyamine metabo… Read More
2020-09-02 02:13
A prealbumin blood test measures prealbumin levels in your blood. Prealbumin is a protein synthesized in your liver. It helps carry thyroid hormones and vitamin A through your bloodstream as… Read More
2020-08-27 04:03
When clinical studies find that there are potentially dangerous proteins on cells, researchers hope to shrink themselves into mini-surgeons, specifically eliminate problematic protein molecu… Read More
2020-08-27 04:01
Existing research results indicate that the body’s metabolic homeostasis is closely related to body aging. The process of cellular energy production affected by metabolic stress w… Read More
2020-07-27 03:51
Tumor is one of the major challenges that modern medicine must face. In order to find effective diagnosis and treatment methods, researchers actively explore the process and molecular b… Read More
2020-07-27 03:45
Liver cancer is the fifth most common cancer in the world and the second leading cause of cancer death. Cholangiocarcinoma is the second most common liver cancer. It is a malignant… Read More
2020-07-07 08:49
Cytokine storm, also known as cytokine storm syndrome (CSS) or hypercytokinemia, refers to the phenomenon that multiple cytokines, such as TNF-α, IL-1, IL-6, IL-12, IFN-α, IFN-&b&hell…Read More
2020-07-07 08:40
The UK government ’s chief scientific adviser, Patrick Vallance, recently stated that many organizations are conducting blood tests on COVID-19. He said “This will tell us who ha… Read More
2020-07-07 08:30
At present, the outbreak of COVID-19 has spread to more than 200 countries and regions around the world, and the number of confirmed cases has exceeded 6 million. The world is racing to deve… Read More
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