Practical Uses for Quantum Computers In the rapidly evolving field of quantum computing, practical applications are beginning to surface, particularly in the realm of chemistry. These advanc… Read More

Driven by increasingly mature technologies, ADC payloads have undergone three generations of innovation. In the first generation of ADC drugs, traditional chemotherapy agents such as me… Read More

Chemical drugs can be classified into three categories based on their binding modes: covalent drugs, non-covalent drugs, and covalent reversible drugs. Covalent drugs have strong binding abi… Read More

Among the first-generation ADC drugs, traditional chemotherapy drugs such as methotrexate, vinblastine, and doxorubicin were used as cytotoxic payloads. However, due to insufficient cyt… Read More

Covalent drugs refer to those drug molecules that form strong bonds with receptors through the formation of covalent bonds. It all began with aspirin in 1899, gained prominence with ibr… Read More

What are enzymes? Enzymes are peculiar proteins essential in furthering and encouraging biochemical reactions in living organisms. The catalyst characteristics of enzymes speed up the pro… Read More

In recent years, PROteolysis TArgeting Chimeras (PROTAC), which utilizes the cell’s own degradation mechanisms to eliminate specific disease-related proteins, has emerged as one of the… Read More

What Is The Role Of Enzymes In The Human Body – ). Its main function is to act as a catalyst to speed up a reaction without itself being changed in the process. Enzymes are generally p… Read More

What Is The Role Of Enzymes In Chemical Reactions – )’s main function is to act as a catalyst to speed up a reaction without changing itself in the process. Enzymes are usually p… Read More

Introduction Enzyme activity is regulated by a variety of mechanisms, including: Substrate availability: The concentration of substrate molecules can affect the rate of enzyme-catalyzed reac… Read More

Targeted protein degradation (TPD) technology has been developed rapidly in recent years, especially proteolysis targeting chimeras (PROTACs). To date, a large number of degraders have been… Read More

 PROTEINS: FUNCTIONS & CLASSIFICATIONWHAT ARE PROTEINS?The word "Protein" was coined by J.J. Berzelius in 1838 and was derived from the Greek word "Proteios" meaning the ‘firs… Read More

Proteasome is the main pathway by which misfolded proteins and other proteins are proteolyzed during protein synthesis. It is found in all eukaryotic cells, archaea and some bacteria and is… Read More

SARS-CoV-2 belongs to the family of Coronaviruses, β-coronaviruses, and is a different species in the same family as the SARS virus (Severe Acute Respiratory Syndrome Coronavirus, SARS… Read More

Coronavirus type 2 of severe acute respiratory syndrome (SARS-cov-2) causes coronavirus disease (COVID-19) in humans and there is no cure. In the fight against COVID-19 epidemic, traditional… Read More