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What is etiology and pathophysiology of pneumonia?

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What is Pneumonia?

Pneumonia is termed an acute respiratory form of infection affecting the lungs, typically an infection that inflames the air sacs in one or both lungs. The air sacs could be filled with fluid or pus which can cause cough, chills, fever, and difficulty in breathing. Pneumonia can vary from light fever to life-threatening. It can cause serious damage to infants, young children, people older than age 65, people with health problems, and people with weakened immune systems.



Photo: Google Image

What are the symptoms of pneumonia?

The signs and symptoms of pneumonia vary from mild to severe and it also depends on factors such as the type of germ which is causing the infection, the age of the individual, and overall health. Some of the signs and symptoms of pneumonia are following;

1. Pain in the chest during breathing and coughing.

2. Rapid heartbeat.

3. High temperature

4. Sweating and shivering.

5. Feeling unwell most of the time.

6. Breathing difficulty.

7. Fatigue.

 8. Wheezing.

Newborns and infants may not show the same symptoms of infection. They may vomit, have a fever, or cough, appear restless or tired, or have difficulty in breathing and eating.

What are the different causes of pneumonia?

Mostly bacteria and viruses that we breathe in the air are the real cause of pneumonia because the air contains germs in the form of bacteria and viruses. Our body usually prevents these germs from infecting the lungs but sometimes these germs become overpowering and enter our body and the damages the normal functioning of our body.

How to classify pneumonia?

Pneumonia is classified in step with the forms of germs that reason it and where you purchased the infection.

1. Community-Obtained pneumonia

Community-Obtained pneumonia is the maximum not unusual kind of pneumonia. It happens out of doors of hospitals or other fitness care centers. It may be because of:

 Bacteria: The most common cause of bacterial pneumonia in the U.S. is Streptococcus pneumonia. This kind of pneumonia can arise on its own or after you have had a chilly or flu. It may affect one part (lobe) of the lung, a condition known as lobar pneumonia.

 Bacteria-Like Organisms: Mycoplasma pneumonia also can motivate pneumonia. It generally produces milder signs than different forms of pneumonia. Taking walks pneumonia is an informal call given to this form of pneumonia, which commonly isn't always intense sufficient to require mattress relaxation.

 Fungi: This sort of pneumonia is not unusual in human beings with chronic health troubles or weakened immune structures, and in human beings who have inhaled big doses of the organisms. The fungi that motivate it may be found in soil or hen droppings and vary depending upon geographic region.

   Viruses, Including COVID-19:  A number of the viruses that cause colds, and the flu can cause pneumonia. Viruses are the maximum commonplace reason for pneumonia in youngsters more youthful than five years. Viral pneumonia is generally moderate. But in a few cases, it is able to grow to be very critical. Coronavirus 2019 (COVID-19) may additionally cause pneumonia, which can emerge as excessive.

   2. Hospital-Obtained pneumonia

Some humans capture pneumonia throughout a hospital stay for some other illness. Hospital-received pneumonia may be serious because the bacteria causing it is able to be greater immune to antibiotics and because the people who get it are already unwell. Folks that are on respiratory machines (ventilators), regularly used in intensive care gadgets are at higher hazard of this kind of pneumonia.

3. Healthcare-acquired pneumonia

Healthcare-acquired pneumonia is a bacterial contamination that takes place in people who stay in lengthy-term care facilities or who acquire care in outpatient clinics, including kidney dialysis centers. Like medical institution-obtained pneumonia, health care-received pneumonia may be due to bacteria that are more proof against antibiotics.

4. Aspiration pneumonia

Aspiration pneumonia takes place while you inhale food, drink, vomit, or saliva into your lungs. Aspiration is more likely if something disturbs your regular gag reflex, which includes mind damage or swallowing problem, or excessive use of alcohol or drugs.



Photo: Google Image

What are the risk factors of pneumonia?

Pneumonia can affect all and sundry. However, the age corporations at the highest risk are:

• Children who are 2 years old or younger.

• Individuals who are age sixty-five or older.

Other risk factors include:

 Being hospitalized: You are in more danger of pneumonia in case you're in a sanatorium intensive care unit, in particular in case you're on a system that facilitates your breathing (a ventilator).

Continual disease: You're more likely to get pneumonia if you have asthma, chronic obstructive pulmonary ailment (COPD), or coronary heart disorder.

 Smoking: Smoking damages your frame's herbal defense against the bacteria and viruses that cause pneumonia.

 Weakened or Suppressed Immune System: People who have HIV/AIDS, who've had an organ transplant or who get hold of chemotherapy or long-time period steroids are at hazard.

What are the complications of pneumonia?

In spite of remedy, some humans with pneumonia, particularly those in excessive-danger corporations, may also revel in complications, together with:

 Bacteria within the bloodstream (bacteremia): Bacteria that input the bloodstream from your lungs can spread the infection to other organs, potentially inflicting organ failure.

Difficulty respiratory: In case your pneumonia is extreme or you have got chronic underlying lung sicknesses, you could have trouble inhaling enough oxygen. You could want to be hospitalized and use a breathing system (ventilator) while your lung heals.

Fluid accumulation across the lungs (pleural effusion): Pneumonia may cause fluid to accumulate within the skinny area between layers of tissue that line the lungs and chest cavity (pleura). If the fluid becomes infected, you could need to have it tried through a chest tube or eliminated with surgery.

 Lung abscess: An abscess happens if pus paperwork is in a hollow space within the lung. An abscess is normally handled with antibiotics. Sometimes, surgical procedures or drainage with a long needle or tube positioned into the abscess is needed to do away with the pus.

How to prevent pneumonia?

Pneumonia can be prevented by using the following preventive measures;

Get vaccinated: Vaccines are available to prevent a few forms of pneumonia and the flu. Talk with your medical doctor about getting those photographs. The vaccination suggestions have changed through the years so make sure to study your vaccination popularity together with your doctor even if you do not forget formerly receiving a pneumonia vaccine. Make sure children get vaccinated: Doctors recommend a different pneumonia vaccine for children more youthful than age 2 and for children a long time 2 to five years who are at particular threat of pneumococcal disease. Kids who attend group toddler care middle have to additionally get the vaccine. Doctors also suggest flu shots for kids older than 6 months

 Practice good hygiene: It includes washing hands properly, wearing clean clothes, breathing fresh air, doing general body exercise (e.g., morning walk) drinking clean water, and eating healthy food.

Don't smoke: Smoking damages and weakens the lungs so the lungs have higher chances of catching germs which results in pneumonia.

Keep your immune system strong: Sleep well, perform exercise on daily basis and eat healthy food.





 Reference:

Patrick M Meyer Sauteur, Challenges and Progress Toward Determining Pneumonia Etiology, Clinical Infectious Diseases, Volume 71, Issue 3, 1 August 2020, Pages 514–516, https://doi.org/10.1093/cid/ciz879



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