American Express My Offer Apply for an American Express credit card online (assuming the applicant passes the prequalification requirements) AMEX.us/MyOffer is managed by the American Express Company Any general questions in regards to the credit card application can be directed to 1-800-528-4800 In order to determine of the application qualifies for a life changing American Express card they will be asked to provide their full name, last 4 digits of their SSN,