Jerusalem in Israel is the most expensive city for expats in the Middle East as at April 2018, followed by Doha in Qatar.

Luanda in Angola is the most expensive city in the world for an expatriate professional migrant to live in as at April 2018, followed by Hong Kong and Singapore. The top ten most expensive cities in the world comprise two from Africa, Luanda (1); Bangui (10), three from Asia-Pacific, Hong Kong (2); Singapore (3); Tokyo (8), three from Europe, Zurich (4); Oslo (5); Geneva (6), and two from America, Hamilton (7); Manhattan NY (9).

Notably, no city in the Middle East is ranked in the top 10 most expensive cities in the world.

https://www.xpatulator.com/cost-of-living-article/Middle-East-Expat-Cost-of-Living-Comparison_707.cfm