North carolina the land of the sky offers umpteen job opportunities to Physician Assistants and is one of the states with most licensed physician assistants. It is one of the states with lots of openings for physician assistants in general practice as well as in specialized practice like orthopedics, emergency medicine, pediatrics to name a few. In general physician assistants in orthopedics find the best payrate as physicians delegate essential work of patient history collection, comparison, ordering diagnostic testing, interpreting results, prescribing medicines as they do have authority to be covered by medicare and medicaid. Here is an average range on what a physician assistant does make in the state of north carolina: Lower Range - $80000 Median Range - $100000 Higher range - $125000+ Again it depends on kind of practice they support, type of practice they work for to name a few