Interessante configurazione 

[mysqld]
max_connections=200
low_priority_updates=1
myisam-recover=backup,force
thread_concurrency=8
concurrent_insert=2
thread_cache_size=32
max_allowed_packet=8M

innodb_buffer_pool_size=512M
innodb_additional_mem_pool_size=10M
innodb_flush_method=O_DIRECT

interactive_timeout = 100
connect_timeout = 60
wait_timeout = 120

tmp_table_size = 256M
max_heap_table_size = 256M
join_buffer_size=2M
read_buffer_size=4M
sort_buffer_size=2M
read_rnd_buffer_size=2M
key_buffer_size=128M
max_allowed_packet=8M
max_connect_errors=10
myisam_sort_buffer_size=64M
query_cache_limit=3M
query_cache_size=64M
query_cache_type=1

[mysqldump]
quick
max_allowed_packet=16M

[mysql]
no-auto-rehash

[isamchk]
key_buffer=128M
sort_buffer=128M
read_buffer=4M
write_buffer=2M

[myisamchk]
key_buffer_size = 128M
sort_buffer_size = 128M
read_buffer = 4M
write_buffer = 2M

[mysqlhotcopy]
interactive-timeout