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Artificial Kidney-Project

This abstract explains an innovated design of an implantable artificial kidney. The proposed design introduces a dialisit-free miniature size complex of cells, each built as a rectangular passage through which Blood flows. Two plate electrodes cover two sides of the passage and two special semipermeable membranes engulf the electrodes without touching them. Each membrane is separated by a few millimeters from the adjacent electrode, and the two membranes themselves are at distance from each other. An electric field is applied between the two electrode plates. This field will force the blood Ions to migrate across a membrane towards the targeted electrodes. The migrating blood ions will generates an ionic current responsible for main ions filtration. The field magnitude is gradually varied and results are then recorded. The spacing between the two membranes is also varied to study its effect on the concentration of ions in the main blood stream and near the electrodes where the filtered waste products rich in ions gather after crossing the semi-permeable membrane. The overall ionic current is generated from the diffusion and the migration currents that obey the general Nernst-Planck equation. One cell model was constructed using inert electrodes. The instrument is capable of regulating the amount of water excretion by controlling a required range of suction pressure (micro-pump) relative to the incoming blood pressure to enhance the generated osmotic pressure across the membrane. The nitrogenous waste products could be removed by simple diffusion enhanced with an applied ultra-filtration pressure. Preliminary results showed a 20% separation of ions from the main stream. Despite of the difficulties encountered during model construction and performing the experiments using the one-cell compartment, the obtained results show a significant reduction of the time required for the patient to attend hospital sessions



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Artificial Kidney-Project

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