The ischemic stroke is one of the most common causes of morbidity and mortality for both females and males in developed countries. In addition to the traditional Risk factors, such as smoking, hyperlipidemia, overweight, stress, and poor dietary habits, the role of a night job and sleep alterations in the risk of stroke occurrences has been recently investigated.

After 10 years of continuous rounds of a nighttime job, nurses showed an Increased Risk of stroke by 15-18% compared to daytime nurses. The study has collected data from 189,000 nurses who were involved in night rounds more than three times a month during 24 years. Every 2-4 years, data about the presence of other cardiovascular Risk Factors have been updated: overall, more than 10,000 new cases of coronary disease have been reported.

The night job resulted particularly dangerous during the first months after starting rounds. The explanation of this increased risk of Cardiovascular Disease seems to be related to sleep pattern alteration and poor sleep quality. A positive modulation of sleep patterns and better organization of work times may contribute to reducing the risk of cardiovascular disease for this class of workers and to keep healthier all night workers.