The Green Bay Packers and San Francisco 49ers have competed in the postseason in the recent past, and will renew their rivalry in the NFC Divisional playoffs on Saturday. Green Bay comes in off of a first round bye, while the 49ers will look to win a second straight road game to move a step closer to the Super Bowl. In this week’s NFL betting picks, we look at 49ers vs Packers in a dream matchup in the NFC playoffs.

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49ers vs Packers Betting Pick

This game will be played at Lambeau Field at 8:15 PM ET on Saturday, January 22, 2022

Why Bet The 49ers:

The 49ers and Packers played a tight game in their meeting during the regular season, with the Packers barely pulling that game out at the end of regulation. Another tight game can be expected here, as both teams are playing at a high level, and a Packers win wouldn’t be likely to be at a margin of six points or more.

Green Bay is 7-1 against the spread at home, but here is who they have played so far this season at Lambeau: Lions, Steelers, Washington, Seahawks, Rams, Bears, Browns, Vikings. Only two of those teams made the playoffs, and only one was anything close to a contender. Expect a tougher outing for the Packers in this game.

San Francisco held the Cowboys to 4.4 yards per play in the Wild Card round on the road, a yard and a half under the season average for the Cowboys on the season. Assuming Nick Bosa comes back in time to play this game despite his concussion, the Niners should be able to do the same to Green Bay.

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The San Francisco 49ers beat the Dallas Cowboys in Arlington during Wild Card weekend to secure their place in the Divisional round. It was the defense of the Niners that propelled them to their win over the Cowboys, as the San Francisco defense got multiple stops down the stretch to prevent the Cowboys from taking the lead late. Now, the Niners face an even tougher test on defense against the presumptive MVP in Aaron Rodgers and the Packers.

San Francisco did a great job of taking the Cowboys receivers out of the game for the most part on Wild Card weekend. Amari Cooper led all Dallas wide receivers with 64 receiving yards, while CeeDee Lamb had just one catch for the game. Against Davante Adams of the Packers, the Niners will need to do just as good a job in the secondary.

Green Bay Packers

The Green Bay Packers spent Wild Card weekend at home, having earned a first round bye in the playoffs as the top seed in the NFC. They will hope that week off helped them recover from a grueling regular season, without creating any rust that could lead to a slow start against a hungry 49ers team.

While the offense of the Packers has been elite as always with Aaron Rodgers at the helm, the defense of the Packers has been beatable over the last couple of months of the season. Green Bay allowed 28 points or more in five of their final seven games of the year, including to subpar opponents like the Lions, Bears, and Tyler Huntley-led Ravens. They will need to be better this week against a Niners team that can move the ball in so many ways thanks to their versatile star Deebo Samuel, along with perfectly competent air and ground games.

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