Oracle said Mark Hurd, one of the software vendor's two CEOs, is taking a leave of absence for health reasons, nine years after joining the company from Hewlett-Packard.
Larry Ellison, Oracle's founder and chief technology officer, will handle Hurd's responsibilities along with Safra Catz, the other CEO.
The company didn't specify Hurd's health issue or say how long he would be gone and a spokesperson didn't immediately respond to a request for comment.
"Though we all worked hard together to close the first quarter, I've decided that I need to spend time focused on my health," Hurd, 62, said in a statement .
In a separate statement, Oracle reported fiscal first quarter profit of 81 cents a share, excluding certain items, on $9.22 billion in revenue.
Hurd's leave of absence comes after one of Oracle's top executives, Thomas Kurian, departed to become head of Alphabet's Google cloud business in 2018.
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