An international team of researchers has identified a programmable RNA-guided system in Eukaryotes. Eukaryotes encompass plants, animals, fungi, and protists. The newly discovered system is based on a protein called Fanzor. It uses RNA as a guide to precisely target DNA. The researchers demonstrated that Fanzor proteins can be reprogrammed to edit the genome of human cells. Compared to CRISPR/Cas systems, the Fanzor system is more compact and has the potential to be delivered more easily to cells and tissues as therapeutics. RNA-guided DNA-cutting mechanisms across all kingdoms of life…

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