POD staff picks for the “Monday Night Football” matchup between the San Francisco 49ers at Minnesota Vikings.

The NFL closes out Week 7 with a “Monday Night Football” matchup between the San Francisco 49ers and Minnesota Vikings at U.S. Bank Stadium. The 49ers and Vikings have met 48 times in their franchise’s histories, with Minnesota holding a 22-20 regular season advantage, while San Francisco has a 5-1 lead in the postseason.

The big news is on the injury front, where the 49ers will have stud running back Christian McCaffrey available. McCaffrey has scored a touchdown (from scrimmage) in 15 straight games, and if he can get in the endzone in this game, he will become the solo NFL record-holder for this category—currently, he is in a four-way tie for the lead. The 49ers will be without wide receiver Deebo Samuel, but that may not matter much against a Justin Jefferson-less Vikings team.

The good folks over at DraftKings Sportsbook list the 49ers as touchdown favorites in this game and while the entire Pride of Detroit staff are taking San Francisco on the moneyline, but against the spread, a few staff members are flipping over to the Vikings and taking the points.

Here is who each of our staff is picking for Monday night’s game:

Here’s how to watch tonight’s “Monday Night Football” game:

49ers at Vikings

Date: Monday, October 23, 2023
Time: 8:15 p.m. ET
Location: U.S. Bank Stadium, Minneapolis, Minnesota
TV: ABC/ESPN
ABC/ESPN announcers: Joe Buck, Troy Aikman, and Lisa Salters (field reporter)
ESPN2 Manningcast: Peyton and Eli Manning with special guests
Online Stream/Replay: ESPN+, ESPN APP, NFL+ Premium

Enjoy the game and come chat with us in the comments!