The NFL draft is a special event. Every year, the top college football players get to make their childhood dreams a reality and make it to the NFL. It's a rare opportunity for these players. What's even rarer is going 1st overall. Being the first name called on draft night is a special moment. There's a lot of pressure to handle for both the team and the player. Sometimes it's a home run. Other times, it's not. These players were all taken with the first overall pick. Let's discuss how their careers went. This list is specifically for those who were picked first overall after 2000! So, Peyton Manning is ineligible for this specific list.