Objective: To determine whether poor cardiovascular (CV) fitness and exaggerated Exercise blood pressure (BP) and heart rate (HR) were associated with worse brain morphology in later life.
Methods: Framingham Offspring participants (n = 1,094, 53.9% female) free from dementia and CV disease (CVD) underwent an exercise treadmill test at a mean age of 40 ± 9 years.
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