RNA Interference Therapy Targeting Apolipoprotein C-III in Hypertriglyceridemia
D. Gaudet and Others
This randomized controlled trial examined the safety and side effects of the small interfering RNA ARO-APOC3 in healthy volunteers and patients with hypertriglyceridemia and chylomicronemia. ARO-APOC3 was associated with few adverse events and no dose-limiting toxicities.
DOI: 10.1056/EVIDoa2200325
Originally Published: November 17, 2023
Original Article
Use of Win Statistics to Analyze Outcomes in the DAPA-HF and DELIVER Trials
T. Kondo and Others
In this study, we applied win statistics to the DAPA-HF and DELIVER trials, exploring the effect of dapagliflozin on a composite outcome incorporating patient-reported outcomes as well as total heart failure events and cardiovascular deaths.
DOI: 10.1056/EVIDoa2300042
Originally Published: October 24, 2023
Morning Report
A 7-Year-Old Boy with Fever and Dark Urine
T.M. Chuang and Others
A 7-year-old boy with surgically repaired tetralogy of Fallot presented for evaluation of fever and dark urine. How do you approach the evaluation, and what is the diagnosis?
DOI: 10.1056/EVIDmr2300191
Originally Published: October 24, 2023
Patient Platform
Research in the Transformation Zone
E. Boskey
In this Patient Platform, Elizabeth Boskey, Ph.D., describes how her experiences as a clinical research participant have profoundly affected the ways that she does research.
DOI: 10.1056/EVIDpp2300225
Originally Published: October 24, 2023
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Additional Published Content
Physician Jobs
November 21, 2023
Hematology-Oncology
Pennsylvania
Great opportunity for an experienced physician in West Reading
Reading Hospital is seeking a Board-Certified Hematologist/Oncologist to join a community hospital-based and academic practice of 9 physicians and 7 advanced practitioners at the McGlinn Cancer Institute located in West Reading, Pennsylvania. This Hematology/Oncology position is a great opportunity for an experienced physician with a preference for treating general cancer cases in our outpatient community-based practice.....
Neurology
Alabama
Established group in Birmingham seeking neurologist
Come to Birmingham, Alabama and join a recognized neurology group in a gorgeous southern setting. This is an established practice with an excellent community reputation working collaboratively to deliver excellent patient care. Our facility is a Designated Stroke Intervention Hospital and is the recipient of the American Heart Association/American Stroke Association's Get With The Guidelines® Target: Stroke Honor Roll Elite Gold Plus Quality Achievement Award....
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