IM Hematology

Rotation Prep Update

The IM Hematology rotation guide update includes ISTH guidelines for the diagnosis and treatment of thrombotic thrombocytopenia purpura and updated treatment algorithms for newly diagnosed myeloma and β-thalassemia.

Hydrocortisone to Prevent Bronchopulmonary Dysplasia: A Coup de Grâce for Corticosteroids?

From Pages to Practice

Bronchopulmonary dysplasia (BPD) is a common morbidity in preterm infants. At the core of the disease, an insult leads to disruption of normal lung development and ultimately presents as respiratory insufficiency. In the past few decades, the epidemiology of BPD has shifted as our...

Restricted Calories and Eating Times in Weight Loss

Clinical Pearls & Morning Reports

This trial evaluated the efficacy and safety of time-restricted eating as compared with daily calorie restriction for weight loss at 1 year among patients with obesity. Time-restricted eating did not produce additional benefits with regard to the reduction from baseline in body weight, body...

Early-Onset Colorectal Cancer

Clinical Pearls & Morning Reports

Early-onset disease (at

Calling out Impostor Syndrome

Insights on Residency

As chief resident, I have been in a position to observe and mentor students, interns, and residents. I have always believed in the importance of recognition and support in a workplace. On a recent encounter with an intern, as I was praising her for her work, she responded rather unexpectedly!...

Ivosidenib in IDH1-Mutated Acute Myeloid Leukemia

NEJM Quick Take Videos

Ivosidenib, when combined with azacitidine, showed promise in a small, early trial involving patients with IDH1-mutated acute myeloid leukemia, but randomized-trial data were needed. New research findings are summarized in a short video.

Inhaled Glucocorticoids in Black and Latinx Adults with Asthma

NEJM Quick Take Videos

Black and Latinx adults are disproportionately affected by asthma, and attempts to address this disparity have been largely unsuccessful. New research findings are summarized in a short video.

Time-Restricted Eating in Weight Loss

NEJM Quick Take Videos

Daily calorie restriction is a common weight-loss strategy, but diet trials have shown only modest success in sustained weight loss. Time-restricted eating offers another approach. New research findings are summarized in a short video.

Effectiveness of Covid-19 Vaccines against the Omicron Variant

NEJM Visual Abstract

In a large case–control study in England, immunity to the omicron variant was very low and less than that to the delta variant 20 weeks after the second vaccine dose, regardless of the initial vaccine type. A booster dose of one of the mRNA vaccines improved efficacy to approximately 65 to...

Screening for Melanoma: The Controversy Continues

NEJM JW Clinical Spotlight

Risk for Adverse Ocular Events When Using Erectile Dysfunction Drugs

NEJM Journal Watch Summaries

Network Meta-Analysis Identifies Best Psychosocial Interventions for Chronic Low Back Pain

NEJM Journal Watch Summaries

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