If you’ve tried natural methods to kill Poison Ivy and they aren’t working, you need the best poison ivy killer spray. These powerful sprays eliminate poison ivy down to the root for effective removal.
The hardest weeds to kill are the type that need to be eliminated down to the root. Poison ivy is one of them. However, killing down to the roots is not an easy task.
When you try to pull up poison ivy, it can cause severe reactions, resulting in an itchy rash. One of the better methods of killing poison ivy is to use a chemical compound. Our list below shows the best poison ivy killer sprays.
I built this list by examining the positive and negative reviews about poison ivy killers from the verified purchasers across multiple websites, and examining the chemical makeup of the solution. With so many fake reviews on Amazon now, it’s important to filter out the fake reviews, like I did.
Read all the comparison, pros, cons, specifications, ratings, my favorites, and reviews of these poison ivy killers, so you can make a purchasing decision wiser and with proper knowledge.
- Chapin 20541 One Gallon Garden Sprayer
- Chapin 48-Ounce Farm and Field Hand Sprayer
Roundup Brush and Poison Ivy Killer Spray
Well known option
Roundup is a well respected and leading brand in weed killers. Their poison ivy killer spray herbicide is effective and includes a guarantee. If the product doesn’t work, Roundup will refund you. It’s easy to use, and kills quickly.
What We Like
- Great price point
- Kills a variety of bushes, not just poison ivy
- Penetrates the root
- Rainproof
- See results in as little as 24 hours
What Could Be Improved
- Not the most potent killer on the list
Full Review
Roundup poison ivy killer spray utilizes two different ingredients to penetrate the waxy leaves of brushes and ivy to penetrate and kill down to the root. It kills poison ivy, poison oak, poison sumac, and invasive shrubs.
In is little as 30 minutes, the spray becomes rainproof, so use it when there is no chance of rain. It can be used in a wooded area, or as a spot treatment. Can also kill stumps and prevent the ivy from growing back.
Comes with a spray wand and multiple size options. It kills in as little as 24 hours, includes a guarantee, and is very easy to use.
Ortho GroundClear Poison Ivy Killer
Best easy apply option
Ortho makes a great killer to take out tough weeds and bushes. It works in as little as 24 hours, and penetrates deep down into the root. The comfort wand allows you to spray multiple bushes comfortably.
What We Like
- Kills over 60 weeds down to the roots
- Affects plant in as little as 24 hours
- Rainproof after 2 hours
- Works on tough to reach places
- No pumping required
- Good spray radius and distance
What Could Be Improved
- None noted
Full Review
Ortho GroundClear poison ivy killer spray kills over 60 tough weeds and brushes including common pests like poison oak, kudzu, woody plants, blackberry brush, vines, and others. It’s powerful formula penetrates down to the roots.
It is a fast acting spray that starts to affect plants in as little as 24 hours. Just plug in the comfort wand into the side of the bottle and apply a generous coat to the pesky weed. The comfort wand allows you to avoid bending down, and provides a great and even spray.
Use this sprayer around the garden, in the woods, and along structures. For well dug in and large weeds, you might need to apply second and third coat.
Bonide 506 Poison Oak and Ivy Herbicide
Best lawn-safe option
Bonide created a powerful, yet gentle, herbicide to rid your yard of poison ivy and various other lawn weeds. The sprayer is designed to kill weeds, while leaving grass unharmed. It kills down to the roots, and results show in as little as 36 hours.
What We Like
- Controls a wide variety of lawn weeds
- Rainproof within a few hours
- Won’t kill lawn grass
- No mixing or pouring required
- Lightweight and easy to use
What Could Be Improved
- Can take up to four weeks to completley kill weeds
Full Review
Bonide spray controls poison ivy, oak, dandelion, clover, thistle, ground ivy, creeping charlie, chicory, and many other weeds. The best part is it doesn’t kill grass like many other options on this list.
It arrives ready to use, with no preparation required. Just point and spray. Effects become noticeable in 36 hours, but it can take up to four weeks for the plant to completely die.
Southern Ag Crossbow
Best heavy-duty option
For people looking to clear out a huge area of weed, not just poison ivy, this is your best option. It is a concentrate and doesn’t come ready to spray, but this one gallon bottle makes 96 gallons worth of treatment.
What We Like
- It covers a large area, but needs to be mixed with water
- Mixes easily in a weed sprayer
- Makes up to 96 gallons of herbicide
- Destroy leaves quickly and effectively
What Could Be Improved
- Doesn’t include a sprayer
Full Review
Southern Ag Crossbow is a heavy-duty poison ivy killer spray that comes in a concentrated formula to destroy roots and plants. The one gallon bottle makes up to 96 gallons of spray.
The bottle doesn’t include a sprayer, so we recommend using a backpack sprayer to easily apply the solution.
It is one of the most effective killers on our list. We recommend this for tough brush, or large areas.
Monterey Poison Ivy Herbicide
Also prevents growth
The Monterey brush and vine control concentrate kills poison ivy and brush, while also taking out thick trunks. Best of all, spray it in areas prone to weeds in order to prevent future growth.
What We Like
- Control stumps
- Prevents the growth of poison ivy
- It’s concentrated, but requires a spreader
- Covers a large area
- Works fast
What Could Be Improved
- Not the most effective on existing poison ivy
Full Review
This poison ivy killer spray works best in the early stages of growth. When you first start to notice the poison ivy growing, spray it with the Monterey concentrate to destroy the stump and prevent future growth.
This product comes as a concentrate and will require you to mix the chemical with water before application occurs. Freshly cut brush stumps will require undiluted application.
It is designed for residential use and is not for use in farming operations.
Check out these other weed killers to keep your lawn clean:
- Best Dandelion Killer
Frequently Asked Questins
How to make a natural poison ivy killer spray?
If the chemical sprays we listed above aren’t what you are looking for, it’s fairly easy to make a natural solution, but it will not be as effective.
Add a tablespoon of dish soap, one cup of salt, and gallon of water together. Stir the solution until mixed and add to your sprayer of choice. This solution is effective, but it requires multiple treatments, and might not work against tough and overgrown options.
Additionally, you can spray distilled white vinegar, which will also require multiple treatments. Although these sprays are natural, you should still be careful when spraying as it will kill neighboring plants.
What’s better: natural vs chemical poison ivy killers?
This really comes down to your personal preference. Chemical options are obviously more potent, work faster, and last longer. However, natural options do work, they just require more treatment and might require you to dig up the plant to prevent it from coming back.
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