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Malignant Hyperthermia

Malignant Hyperthermia

Malignant Hyperthermia is a inherited muscle disorder (autosomal dominant). Mechanism Involves a sudden rise in release of bound (stored) calcium of the sarcoplasm, stimulating contraction and a hypermetabolic state. Oxygen consumption increases by up to 3x normal, and body temperature may rise as fast as 1oC every 5 min, reaching as high as 43oC. The condition occurs during or within



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Malignant Hyperthermia

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