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Resveratrol for Skin: Benefits and Risks

Antioxidants benefit the Skin, which is why most people interested in skin care have heard of them. Although it is claimed that they can turn back the hands of time, you can find them in various creams, gels, and serums.

Did you know that your favorite bottle of red wine naturally contains an antioxidant that is one of the most powerful available? The following provides detailed information on how Resveratrol can improve the appearance of one’s skin.

Table of Contents

What is Resveratrol?

A plant compound known as resveratrol can be found in various foods, including grapes, red wine, certain berries, peanuts, and others. It protects the skin from free radicals that can cause damage and has antioxidant properties.

Research published in 2010 demonstrated that the free radical molecules that resveratrol protects against are the primary cause of aging skin and are capable of causing damage to any cell in the body [1].

Researchers have found that resveratrol may protect against cardiovascular disease, neurological disorders such as Alzheimer’s disease, and even certain types of cancer [2,3,4,5].

Resveratrol for Skin Benefits

For Rough Skin

The same research conducted in 2012 discovered that after 60 days of taking a resveratrol supplement, there was an improvement in the texture of the skin [6].

For Dry Skin

It is possible that you will no longer experience dry patches if resveratrol is introduced into your body.

A dietary supplement contained an active ingredient that was investigated in a pilot study that took place in 2012 and was found to have a hydrating effect [6]. Research published in 2020 found that resveratrol is effective in treating eczema and psoriasis [3].

For Redness

Due to the calming effects of resveratrol, a study in 2013 discovered that it could also reduce the inflammation and redness of the skin [7].

Environmental Factors Skin Damage

Your skin is susceptible to damage from various environmental factors, such as the sun and pollution.

Researchers have found that resveratrol can protect against ultraviolet (UV) damage and reduce pigmentation caused by the sun [8,9].

For Aging

Resveratrol is known to have the ability to delay the aging process in the skin, which is one of its most significant advantages.

As we get older, the natural collagen and elastin in our bodies begin to deteriorate.

Antioxidants are thought to protect against the effect that damage caused by free radicals has on aging, which occurs faster.

As discussed earlier, resveratrol can have a dual effect, which includes eliminating free radicals and enhancing antioxidant levels. As a result, your skin will be better able to defend itself and heal [10].

According to a study conducted in 2014, applying resveratrol topically to the skin for twelve weeks significantly improved fine lines, wrinkles, and elasticity [10].

Resveratrol With Ferulic Acid

One of the most well-liked formulations for skin care products contains both resveratrol and ferulic acid, yet another antioxidant. The application of an antioxidant cream containing resveratrol and ferulic acid is shown to produce favorable results in the research that was conducted on the topic [11].

How and When to Use Resveratrol

Resveratrol is offered as dietary supplements, moisturizers, and serums; however, topical application of the compound yields the best results.

Research published in 2017 demonstrated that resveratrol is light-sensitive. As a result, it is even more prudent to apply it at night [12].

Whether or not you should include it in your daily skincare routine depends on the product you use.

If it is packaged in a richer night cream, you should apply it after finishing the rest of your evening routine. On the other hand, if you purchase a lightweight serum containing resveratrol, you can use it earlier.

To begin, you need to make sure that you cleanse, exfoliate, and tone (if you do all of these things).

Resveratrol-Rich Foods That You Should Try

Red wine, grapes, peanuts, and dark chocolate are some foods high in resveratrol and can be added to your diet.

You would need to consume a significant amount of resveratrol to see a difference in your skin’s health if you followed this diet, although it may improve your skin’s health overall.

The beneficial properties of resveratrol will penetrate the skin directly, making topical application of the compound a more effective method of administration than oral consumption.

Dosage

Taking resveratrol orally in doses of up to 1000 milligrams daily is considered safe. One thousand grams of resveratrol was given to participants in Japan for the purpose of research, and it was found to be both safe and beneficial to the participant’s health [13].

Are There Any Negative Effects of Resveratrol?

Resveratrol is widely regarded as perfectly safe for any skin type.

Although scientific research has demonstrated that resveratrol benefits the skin, using it may cause some unwanted side effects. Ingestion of high doses of resveratrol is associated with the most common adverse effect, which is stomach upset.

At doses of one gram per day, the research indicates that resveratrol does not appear to have any adverse side effects. However, those with non-alcoholic liver disease reported vomiting, nausea, and liver dysfunction after consuming 2.5 grams or more than the recommended amount [14].

In addition, before taking it in supplemental form, you should consult with a medical expert to ensure that doing so is safe.

Precautions and Warnings

As a source of resveratrol, red wine shouldn’t be consumed while pregnant or breastfeeding for obvious reasons.

The topical application of resveratrol is not thought to pose any significant health risks. However, people who have bleeding disorders should steer clear of resveratrol because it has the potential to inhibit the natural process of blood clotting, which can lead to an increased risk of bleeding. Because of this, you should avoid taking resveratrol in the days leading up to your surgery.

Additionally, resveratrol is well known to be strongly associated with the female hormone estrogen. If your doctor has diagnosed you with the condition that does not support the presence of excessive estrogen, then you should steer clear of this antioxidant.

Conclusion

Resveratrol is a powerful component that should be considered if you want to enhance the health and appearance of your skin.

It is simple to include in any skincare routine and has the potential to slow down the effects of aging on the skin.

Including foods rich in antioxidants in your diet is another step that could be beneficial.

On the other hand, the most reliable method is to apply it straight to the affected skin area.

Disclaimer: This article is only a guide. It does not substitute the advice given by your healthcare professional. Before making any health-related decision, consult your healthcare professional.

Editorial References And Fact-Checking

  1. Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy reviews, 4(8), 118–126. https://pubmed.ncbi.nlm.nih.gov/22228951/
  2. Ndiaye, M., Philippe, C., Mukhtar, H., & Ahmad, N. (2011). The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges. Archives of biochemistry and biophysics, 508(2), 164–170. https://pubmed.ncbi.nlm.nih.gov/21215251/
  3. Gugleva V, Zasheva S, Hristova M, Andonova V (2020) Topical use of resveratrol: technological aspects. Pharmacia 67(2): 89-94. https://doi.org/10.3897/pharmacia.67.e48472
  4. Sawda, C., Moussa, C., & Turner, R. S. (2017). Resveratrol for Alzheimer’s disease. Annals of the New York Academy of Sciences, 1403(1), 142–149. https://pubmed.ncbi.nlm.nih.gov/28815614/
  5. Ko, J. H., Sethi, G., Um, J. Y., Shanmugam, M. K., Arfuso, F., Kumar, A. P., Bishayee, A., & Ahn, K. S. (2017). The Role of Resveratrol in Cancer Therapy. International journal of molecular sciences, 18(12), 2589. https://pubmed.ncbi.nlm.nih.gov/29194365/
  6. Buonocore, D., Lazzeretti, A., Tocabens, P., Nobile, V., Cestone, E., Santin, G., Bottone, M. G., & Marzatico, F. (2012). Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebocontrolled, double-blind study. Clinical, cosmetic and investigational dermatology, 5, 159–165. https://pubmed.ncbi.nlm.nih.gov/23071399/
  7. Ferzli, G., Patel, M., Phrsai, N., & Brody, N. (2013). Reduction of facial redness with resveratrol added to topical product containing green tea polyphenols and caffeine. Journal of drugs in dermatology : JDD, 12(7), 770–774. https://pubmed.ncbi.nlm.nih.gov/23884488/
  8. Boo Y. C. (2019). Human Skin Lightening Efficacy of Resveratrol and Its Analogs: From in Vitro Studies to Cosmetic Applications. Antioxidants (Basel, Switzerland), 8(9), 332. https://pubmed.ncbi.nlm.nih.gov/31443469/
  9. Wen, S., Zhang, J., Yang, B., Elias, P. M., & Man, M. Q. (2020). Role of Resveratrol in Regulating Cutaneous Functions. Evidence-based complementary and alternative medicine : eCAM, 2020, 2416837. https://pubmed.ncbi.nlm.nih.gov/32382280/
  10. Farris, P., Yatskayer, M., Chen, N., Krol, Y., & Oresajo, C. (2014). Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin. Journal of drugs in dermatology : JDD, 13(12), 1467–1472. https://pubmed.ncbi.nlm.nih.gov/25607790/
  11. Clinical evaluation of an antioxidant cream containing resveratrol, ferulic acid, and vitoptin on photodamaged skin. (2011, February). Journal of the American Academy of Dermatology, 64(2), AB21. https://www.jaad.org/article/S0190-9622(10)01193-X/fulltext
  12. Zhu, X. D., Lei, X. P., & Dong, W. B. (2017). Resveratrol as a potential therapeutic drug for respiratory system diseases. Drug design, development and therapy, 11, 3591–3598. https://pubmed.ncbi.nlm.nih.gov/29290681/
  13. Espinoza, J. L., Trung, L. Q., Inaoka, P. T., Yamada, K., An, D. T., Mizuno, S., Nakao, S., & Takami, A. (2017). The Repeated Administration of Resveratrol Has Measurable Effects on Circulating T-Cell Subsets in Humans. Oxidative medicine and cellular longevity, 2017, 6781872. https://pubmed.ncbi.nlm.nih.gov/28546852/
  14. Salehi, B., Mishra, A. P., Nigam, M., Sener, B., Kilic, M., Sharifi-Rad, M., Fokou, P. V. T., Martins, N., & Sharifi-Rad, J. (2018). Resveratrol: A Double-Edged Sword in Health Benefits. Biomedicines, 6(3), 91. https://pubmed.ncbi.nlm.nih.gov/30205595/

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