Did Medicine Can Cause Hair Loss?

" It's a well-established fact that anticancer Drugs can cause Hair Loss. The reason for this is that anticancer drugs kill those cells in the body that divide and multiply rapidly, and it just so happens that hair follicle cells are one of the fastest dividing cells in the body. First, the result was also "unjustly killed" by the powerful medicinal power of anticancer drugs.

It is a well-known fact that anticancer drugs can cause hair loss. The reason is that anticancer drugs will kill those cells that divide and multiply rapidly in the human body, and it happens that hair follicle cells are one of the fastest dividing cells in the body, and as a result, they are also "unjustly killed" by the powerful medicinal power of anticancer drugs. . It was once thought that the use of molecularly-targeted anticancer drugs that are more effective against cancer cells (and less on normal cells) could free patients from hair loss — which, frustratingly, has become a molecular target Common adverse reactions to treatment.

So, in addition to the well-known anti-cancer drugs, which other drugs can also cause hair loss in users? Being sick is enough to make people worry, and it is even more sad when there is nothing left on the head of the "treatment" because of the treatment. Responsibility drives medical researchers to collect and sort out many cases of hair loss caused by drugs (other than anticancer drugs), and make classification and statistics. We just took this opportunity to learn about the situation (Table 1).

Category Varieties Number of Cases Proportion (%) Drug Name (Number of Cases) Anti-infective Drugs 174031.75 Albendazole (4), Praziquantel (4), Prothiimazole (1), Dietrine (1), Flucon Azole (1), Ribomycin (1), Ciprofloxacin (2), Thiamphenicol (1), Lamivudine (3), Lincomycin (1), Norfloxacin (2) ), oxytetracycline (1), itraconazole (1), rifampicin (4), ethambutol (1), streptomycin (1), thiocarbamide (1) Circulatory system medication 52923.02 Aspirin Enteric-coated tablets (1), captopril (4), carvedilol (2), metoprolol (1), simvastatin (1), alginate diester sodium (20) hormone and endocrine drugs 51612.70 Propylthiouracil (4), Dexamethasone (1), Metformin (2), Glimepiride (1), Tapazole (9) Digestive System Drugs 61411.11 Omeprazole (1), Proglumide (1), cimetidine (2), ranitidine (7), morphine (1), cimetidine (2) antipsychotics 797.14 aripiprazole (1), valproic acid Magnesium (1), Fluoxetine (2), Lithium (2), Risperidone (1), Clozapine (1), Sulpiride (1) Immunosuppressive drugs 153.97 Azathioprine (5) Chinese medicines and proprietary Chinese medicines 443.17 Saffron (1), Gastrodia elata Armillaria sugar-coated tablets (1), Xiaoke Pills (1), Tripterygium wilfordii (1) Biological products 232.38 Remicade (2), Recombinant human interferon (1) Dermatology drug 132.38 Diyin tablets (3) Hematological drugs 121.59 Heparin (2) Vitamin 110.79 Vitamin E (1) Total 50126100.00

Table 1 Distribution of types of hair loss drugs

In the above "blacklist", more than 120 literature reports on hair loss caused by various drugs were collected, involving 50 drug varieties. From the table, we can see that the proportion of anti-infective drugs is very large. It's surprising that household drugs such as norfloxacin, dexamethasone, and morphine are among the hair killers. In these cases, the severity of hair loss in patients was not uniform, some people fell out completely, and some had plaque; and many people gradually grew back after stopping or changing the medicine.

Obviously, most incidents of drug hair loss go unreported, but Table 1 is indeed informative, because even a preliminary listing is enough to be a warning—the humble aspirin can make the user's thick hair go with it. The wind is blowing!

In fact, the medical community has not yet fully understood the detailed causes of hair loss caused by various drugs, which may be related to the individual differences of the users. If you only look at the phenomenon, there will be obvious inflammation in the hair loss area of ​​the patient, which is a signal that the skin is damaged. Therefore, there is a view that various chemical substances accumulated in long-term medication are likely to cause damage to the skin or hair follicle tissue.

The researchers can caution that intensive observation is especially needed when using drugs like those listed in Table 1. Once the phenomenon of hair loss is found, it should be treated as soon as possible under the guidance of a doctor, and the development of hair loss should be gradually controlled by reducing the dosage of drugs or changing the variety of drugs.

references

Literature analysis of 126 cases of drug-induced hair loss Chen Shufeng Tianjin Pharmacy 2013 Vol.25 No.5

Hair loss caused by non-anticancer drugs Li Zhanmei Capital Medicine, 1999, 6(1)

Clinical Analysis of Drug-induced Hair Loss