With the chemical formula CH3CHCH2O, Propylene Oxide is an organic molecule that is acutely poisonous and carcinogenic. Industrial production of this colourless volatile liquid, which has an odour resembling ether, is widespread. Its main use is in the synthesis of polyether polyols, which are then used to make polyurethane polymers. Although it is frequently employed as a racemic combination, it is a chiral epoxide. To distinguish it from its isomer, 1,3- organic molecule, also known as oxetane, this substance is sometimes referred to as 1,2- organic molecule.

The oxidation of propylene with an organic peroxide is the other common method of obtaining organic molecules. The reaction's stoichiometry is as follows: RO2H + CH3CH=CH2 = CH3CHCH2O + ROH. Four hydroperoxides are used to practise the procedure: In the Halcon process, isobutane is oxygenated to produce t-butanol, which is then converted into t-butyl hydroperoxide. This coproduct can be transformed into MTBE, an additive for gasoline, by dehydrating it to isobutene. Propylene Oxide can also undergo the following reactions. At 250–260 °C, a reaction with aluminium oxide produces propionaldehyde and a little amount of acetone. Acetic acid is the result of the reaction with silver(I) oxide. Isopropanol is produced when sodium-mercury amalgam and water are combined.

The rising demand for propylene oxide from end-use industries is driving the growth of the Propylene Oxide Market in the Asia Pacific region.

Ethylbenzene hydroperoxide is produced when 1-phenylethanol is produced by oxygenating ethylbenzene. Dehydrating this coproduct yields styrene, a valuable monomer. Cumene (isopropylbenzene) was oxygenated to produce cumene hydroperoxide, which was then converted into cumyl alcohol. This coproduct can be converted back to cumene through dehydration and hydrogenation. Sumitomo Chemical commercialised this technique. Ring-opening reactions happen to PO just like they do to other epoxides. Propylene glycol is created using water. Alcohols undergo processes known as hydroxylpropylation that are comparable to ethoxylation. Secondary alcohols are produced by adding Grignard reagents to propylene oxide.