| Phenylalanine |
The important -Amino Acid Phenylalanine (symbol Phe or F) has the chemical formula C9H11NO2. It can be thought of as either a phenyl group in lieu of the terminal hydrogen of alanine or a benzyl group in place of the methyl group of alanine. Because the benzyl side chain is inert and hydrophobic, this important amino acid is categorized as neutral and nonpolar. DNA-coded proteins are biochemically formed using the L-isomer. Tyrosine, the monoamine neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), as well as the skin pigment melanin, are all precursors to phe. The codons UUU and UUC encode it.
Mammal milk naturally contains Phenylalanine. Due to its analgesic and depressive properties, it is employed in the production of food and beverage items and offered as a nutritional supplement. It is a direct precursor to the dietary supplement phenethylamine, a neuromodulator. Phe must be consumed or found in proteins because it cannot be produced by humans or other animals and is therefore an essential amino acid. Eggs, poultry, liver, beef, milk, and soybeans are excellent sources of phenylalanine. Anything sweetened with aspartame, an artificial sweetener, such as diet drinks, diet meals, and medicines, is another major source of phe because aspartame has phenylalanine as one of its metabolites.
Another amino acid that is encoded in DNA, L-tyrosine, is produced physiologically from L-phenylalanine. The subsequent conversion of L-tyrosine to L-DOPA results in the production of dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline). The catecholamines are the three latter substances. The blood-brain barrier is crossed by Phenylalanine Market via the same active transport pathway as tryptophan. The misuse (and eventually limited availability) of the related cofactors, iron or tetrahydrobiopterin, can prevent the formation of serotonin and other aromatic amino acids, as well as nitric oxide, when supplements are taken in excess amounts. The nitric oxide synthase family and the aromatic amino acid hydroxylase family are the appropriate enzymes for those substances.
This post first appeared on Neuronavigation System: Analysis And Overcome, please read the originial post: here
