Abgenta contains an aminoglycoside antibiotic called Gentamicin Sulphate. Gentamicin drops treat specific eye/ear bacterial infections. It works by first, disrupting the outer bacterial membrane integrity. Secondly, Gentamicin in Abgenta binds to 30s ribosomal sub units, prevents the initiation of protein synthesis thereby blocking the metabolism of the bacteria and this then kills the bacteria.
Furthermore, Gentamicin exerts post antibiotic effects characterized by prolonged suppression of bacterial re-growth at sub-inhibitory concentrations. Gentamicin Sulphate offers a wide spectrum of activity which includes susceptible strains of gram-negative organisms such as H.influenza, E.coli, K.pneumoniae, Enterobacter aerogenes, H. aegyptius, and Neisseria species including N.gonorrhea and Pseudomonas aureginosa and successfully managed with Abgenta
Indications
Eye treatment of external ocular infections caused by eye wounds, bacterial infections, acute conjunctivitis, corneal ulcers, blepharitis, keratitis and infections following surgery. Proved significantly effective in reducing postoperative ocular bacterial counts. Achieves cleaner, healthier postoperative eyes with less mucopurulent discharge and eyelid crusting. Ear treatment of bacterial infections of the ears for example otitis externa or otitis media
Dosage
One or two drops topically in the conjuctival sac(s) or ear(s) depending on affected area every four hours, in severe disease, drops may be used hourly, being tempered to discontinuation as the infection subsides. Or use as directed by a physician.
Contraindication
Abgenta is contraindicated in those patients who may be hypersensitive to any of its components. As with all eye preparations, containing Benzalkonium chloride, those using the drops should not wear soft contact lenses during treatment.
Precautions
Prolonged use of antibiotics may occasionally result in overgrowth of non-susceptible organisms including fungi. If new infections appear during treatment, the drug should be discontinued and appropriate measures should be taken.
A burning or stinging reaction that does not go away may mean you are allergic to this product. Stop using and call your prescriber or healthcare professional. Adverse drug reactions are not common with ophthalmic preparations. In some circumstances this medicines may not be suitable for you
If you are pregnant or intending to become pregnant
If you are breast-feeding a baby
