Coram, is a dihydropyridine derivative, slightly soluble in water and sparingly soluble in ethanol. Amlodipine (Coram) is a calcium ion flux inhibitor (slow channel blocker or calcium ion antagonist inhibits the transmembrane influx of calcium ions into cardiac and smooth muscle). The mechanism of the antihypertensive action of Amlodipine is due to direct relaxant effect on vascular smooth muscle.
The precise mechanism by which Amlodipine relives angina has not been fully determined but Amlodipine reduces total ischemic burden by the following actions
The precise mechanism by which Amlodipine relives angina has not been fully determined but Amlodipine reduces total ischemic burden by the following actions
