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Toujeo (insulin glargine)

What is Toujeo?

Toujeo is a brand-name remedy medication. It’s used to provide form 1 and form 2 diabetes.

Toujeo contains a form of insulin called insulin glargine, that is personal as a long-acting insulin.

Clinical studies tested Toujeo in people with form 1 or form 2 diabetes. The studies showed that after 26 weeks of treatment, Toujeo lowered fasting Blood Sugarine Levels by 17 to 61 mg/dL and hemoglobin A1c (HbA1c) by 0.4 to 1.42.

Toujeo is accessible in dual opposite prefilled pens that are used to inject insulin underneath a skin (subcutaneous).

  • Toujeo SoloStar: This coop contains 450 units of insulin glargine in 1.5 mL of solution. It can give adult to 80 units of insulin glargine in a singular injection.
  • Toujeo Max SoloStar: This coop contains 900 units of insulin glargine in 3 mL of solution. It can give adult to 160 units of insulin glargine in a singular injection.

Toujeo generic

Toujeo is a brand-name drug. It’s not now accessible as a general drug.

Toujeo contains a long-acting form of insulin called insulin glargine. Insulin glargine is also accessible as a brand-name drugs Lantus and Basaglar.

Toujeo side effects

Toujeo can means amiable or critical side effects. The following list contains some of a pivotal side effects that competence start while holding Toujeo. This list doesn’t embody all probable side effects.

For some-more information on a probable side effects of Toujeo, or tips on how to understanding with a discouraging side effect, speak with your alloy or pharmacist.

More common side effects

The some-more common side effects of Toujeo can include:

  • respiratory infections such as a common cold, flu, or bronchitis
  • cough
  • low blood sugarine (hypoglycemia)
  • fluid retention, with flourishing of your arms or legs
  • weight gain
  • pain, rash, swelling, or itchiness during a injection sites
  • skin thickening or pits during a injection sites

If these side effects are severe, speak to your alloy or pharmacist.

Serious side effects

Serious side effects from Toujeo aren’t common, though they can occur. Call your alloy right divided if we have critical side effects. Call 911 if your symptoms feel life-threatening or if we consider you’re carrying a medical emergency.

Serious side effects and their symptoms can embody a following:

  • Severely low blood sugarine levels (hypoglycemia). Symptoms can include:
    • fatigue
    • hunger
    • dizziness
    • sweating
    • shaking
    • blurry vision
    • confusion
    • headache
    • irritability
    • loss of alertness and coma
  • Low potassium levels (hypokalemia). Symptoms can include:
    • fatigue
    • muscle cramps
    • weakness
    • rapid heartbeat
    • pounding chest
    • heart arrhythmia
  • Severe allergic reaction. Symptoms can include:
    • trouble breathing
    • itchy skin
    • flushing
    • rash
    • anxiety
    • swelling of mouth and throat

Rash

Rash, or redness and itching, infrequently occurs around a injection site in people who use Toujeo. It’s not famous how mostly this occurs.

Weight benefit or loss

Weight benefit can start in some people who use Toujeo. This is a side outcome that can start with all insulin products. How many weight benefit occurs with Toujeo isn’t clear. In studies of a identical form of insulin (Lantus), weight benefit of adult to about 2 pounds occurred over 28 weeks of treatment.

Weight detriment isn’t a side outcome that has occurred in studies of Toujeo.

Hypoglycemia

Low Blood Sugarine (hypoglycemia) is one of a many common side effects of all forms of insulin, including Toujeo.

In studies of people holding Toujeo, amiable hypoglycemia occurred in adult to 69 percent of people with form 1 diabetes, and adult to 37 percent of those with form 2 diabetes.

Severe hypoglycemia occurred in about 5 percent to 7 percent of people with possibly form of diabetes. The risk of hypoglycemia was larger for people who perceived Toujeo in multiple with other forms of insulin.

If we mostly have low blood sugarine levels or have critical hypoglycemia while holding Toujeo, speak with your alloy about changing your dosage.

Heart failure

Taking Toujeo along with certain diabetes drugs can boost your risk of heart failure, or wear symptoms if we already have heart failure. These drugs are called thiazolidinediones and embody Actos and Avandia.

Symptoms of heart disaster can include:

  • shortness of breath
  • sudden weight gain
  • swollen ankles or feet

If we have symptoms of heart disaster or worsening symptoms, speak with your doctor. You competence need to stop holding thiazolidinediones.

Joint pain

Joint pain isn’t a side outcome that has occurred in studies of Toujeo. It has occurred in as many as 14 percent of people holding Lantus, a really identical form of insulin. Therefore, it competence also start in people who take Toujeo.

Diarrhea

Diarrhea isn’t a side outcome that has occurred in studies of Toujeo. It has occurred in as many as 11 percent of people holding Lantus, a really identical form of insulin. Therefore, it competence also start in people who take Toujeo.


Toujeo vs. Lantus

Toujeo and Lantus are both brand-name drugs that enclose a long-acting insulin. In fact, they enclose a same ingredient, insulin glargine.

The categorical disproportion between Toujeo and Lantus is that Toujeo is some-more strong than Lantus.

(For comparisons of Toujeo with other drugs, see “Toujeo vs. other medications” below.)

Uses

Toujeo is FDA-approved to urge blood sugarine control in adults with form 1 and form 2 diabetes.

Lantus is FDA-approved to urge blood sugarine control in adults and children who have form 1 diabetes and adults with form 2 diabetes.

Drug forms and administration

Both Toujeo and Lantus are given by an injection underneath a skin (subcutaneous). They’re both customarily given once daily.

Side effects and risks

Toujeo and Lantus enclose a same long-acting insulin ingredient, insulin glargine. Therefore, both drugs can means identical common and critical side effects.

More common side effects of Toujeo and Lantus can include:

  • respiratory infections such as a common cold, flu, or bronchitis
  • low blood sugarine (hypoglycemia)
  • fluid retention, with flourishing of your arms or legs
  • weight gain
  • pain, rash, swelling, or itchiness during a injection sites
  • skin thickening or pits during a injection sites

Other common side effects that have been reported in people regulating Lantus include:

  • joint pain
  • headache
  • high blood pressure
  • diarrhea
  • depression

Serious side effects that can start in people regulating Toujeo or Lantus competence include:

  • severe low blood sugarine (hypoglycemia)
  • low potassium levels (hypokalemia)
  • severe allergic reaction

Although these drugs can means mostly identical side effects, there competence be some differences. In one study, Toujeo was reduction approaching to means hypoglycemia than Lantus.

Researchers in one investigate found that people holding Toujeo had reduction weight benefit than people holding Lantus. However, in another study, there was no disproportion in a volume of weight benefit between a dual drugs.

Effectiveness

Toujeo and Lantus have been directly compared in several studies. These studies uncover that Toujeo and Lantus work about equally good for dwindling fasting blood sugarine and hemoglobin A1c (HbA1c) levels in adults with form 1 or form 2 diabetes. (They haven’t been compared for use in children.)

A disproportion between these drugs is that Toujeo competence work for a longer time than Lantus. Toujeo lasts adult to 36 hours, while Lantus works for 20 to 24 hours. Toujeo competence also means some-more quick blood sugarine levels via a day, with fewer low or high blood sugarine events.

Costs

Toujeo and Lantus are brand-name medications. They’re not accessible in general forms.

Toujeo competence cost somewhat reduction than Lantus. The tangible volume we compensate for possibly drug will count on your word plan.


Toujeo dosage

The Toujeo sip your alloy prescribes will count on several factors. These include:

  • the condition you’re regulating Toujeo to treat
  • your age
  • your weight
  • your diet and spin of earthy activity
  • whether you’re already holding insulin
  • your blood glucose spin goals

Typically, your alloy will start we on a low sip and adjust it over time to strech a sip that’s right for you.

The following information describes dosages that are ordinarily used or recommended. However, be certain to take a sip your alloy prescribes for you. Your alloy will establish a best sip to fit your needs.

Forms and strengths

Toujeo is accessible in dual opposite prefilled pens that are used to broach insulin with an injection underneath a skin (subcutaneous).

Toujeo pens

  • Toujeo SoloStar: This coop contains 450 units of insulin glargine in 1.5 mL of solution. It can give adult to 80 units of insulin glargine in a singular injection.
  • Toujeo Max SoloStar: This coop contains 900 units of insulin glargine in 3 mL of solution. It can give adult to 160 units of insulin glargine in a singular injection.

Toujeo coop needles

Pen needles contingency be trustworthy to possibly form of coop before any injection. Needles aren’t enclosed with a Toujeo pens. The manufacturer of Toujeo recommends regulating one of a following coop needles:

  • BD Ultra-Fine
  • Ypsomed Clickfine
  • Owen Mumford Unifine Pens

Dosage for form 1 diabetes

Your sip of Toujeo for form 1 diabetes will count on possibly you’re starting diagnosis with insulin for a initial time or you’re switching from a opposite insulin product to Toujeo.

Starting insulin for a initial time

  • When you’re initial starting diagnosis with insulin, your medical provider will calculate a sum daily insulin requirement for you. This volume is formed on how many we weigh. Usually, a sum daily insulin requirement is 0.2 to 0.4 units per kilogram of physique weight.
  • About one-third to one-half of your sum daily insulin requirement will be given as Toujeo, once daily. The rest of your sum daily insulin requirement will be given as a short-acting insulin. You’ll order it and take it with any of your daily meals.
  • Your medical provider will work with we to conduct your blood sugarine levels. They’ll guard these levels and adjust your insulin sip if needed.

Switching insulin diagnosis to Toujeo

  • When you’re switching from another once-daily, long-acting insulin to Toujeo, your starting sip of Toujeo would approaching be a same as your sip for a other long-acting insulin. After we switch, your medical provider will adjust your sip of Toujeo, if needed. Most people who switch from Lantus to Toujeo need a aloft daily sip of Toujeo than Lantus. This competence be given a physique absorbs Toujeo some-more solemnly than it absorbs Lantus.
  • When you’re switching from a twice-daily NPH insulin (an intermediate-acting insulin), your Toujeo starting sip would approaching be 80 percent of your sum daily NPH insulin dosage. Your medical provider will adjust your sip of Toujeo if needed.

Dosage for form 2 diabetes

Toujeo dosing for form 2 diabetes depends on possibly you’re starting diagnosis with insulin for a initial time or you’re switching from a opposite insulin product to Toujeo.

Starting insulin for a initial time

  • Your medical provider will calculate your Toujeo sip formed on your physique weight. The standard starting sip of Toujeo in people with form 2 diabetes is 0.2 units per kilogram of physique weight. This volume is customarily taken once daily.
  • If you’re holding other diabetes medications, your medical provider competence need to adjust a sip of those drugs when we start holding Toujeo.
  • Your medical provider will work with we to conduct your blood sugarine levels. They’ll guard these levels and adjust your insulin sip and a sip of your other diabetes drugs if needed.

Switching insulin diagnosis to Toujeo

  • When you’re switching from another once-daily, long-acting insulin to Toujeo, your starting sip of Toujeo will approaching be a same as a other long-acting insulin. After we switch, your medical provider will adjust your sip of Toujeo, if needed. Most people who switch from Lantus to Toujeo need a aloft daily sip of Toujeo than Lantus. This competence be given a physique absorbs Toujeo some-more solemnly than it absorbs Lantus.
  • When you’re switching from twice-daily NPH insulin, your Toujeo starting sip would approaching be 80 percent of your sum daily NPH insulin dosage. Your medical provider will adjust your sip of Toujeo if needed.

What if we skip a dose?

What we should do if we skip a sip depends on when we comprehend that you’ve missed a dose. If it’s within about dual hours of your scheduled dose, it should be OK to go forward and take your Toujeo dose. You should customarily be wakeful that you’ll approaching need to adjust a timing of your subsequent sip accordingly.

If it’s been some-more than dual hours given your scheduled dose, speak with your medical provider right away. They can advise we on a best proceed to control your blood sugarine levels.

Be certain not to take a double sip to make adult for a missed dose. This can means dangerous side effects.

It’s a good thought to speak with your alloy in allege about what to do if we skip a dose. They can tell we during what prove we should equivocate holding a missed sip and instead wait for a subsequent dose.

Will we need to use this drug prolonged term?

Yes. Toujeo is used prolonged tenure to control blood sugarine levels in people with form 1 and form 2 diabetes.

What should we do if Toujeo isn’t working?

It’s critical to remember that it can take adult to 5 days for Toujeo to strech a full outcome on your blood sugarine levels. Therefore, it competence not seem like it’s operative when we initial start holding it.

But if you’ve already taken it for 5 days or longer and it still doesn’t seem to be working, speak with your medical provider. They competence need to adjust your Toujeo dosage.

Dosing tips

  • Your blood sugarine levels should be closely monitored when you’re starting or switching to Toujeo.
  • It competence take adult to 5 days for Toujeo to have a full outcome on obscure your blood sugarine levels.
  • Dosage adjustments should customarily be done any 3 or 4 days.
  • Toujeo shouldn’t be diluted or churned with any other insulin products.

Toujeo uses

The Food and Drug Administration (FDA) approves remedy drugs such as Toujeo for certain uses.

Toujeo for diabetes

Toujeo is FDA-approved to control blood sugarine levels in adults with form 1 or form 2 diabetes.

Clinical studies tested Toujeo in people with form 1 or form 2 diabetes. The studies showed that after 26 weeks of treatment, Toujeo lowered fasting blood sugarine levels by 17 to 61 mg/dL and hemoglobin A1c (HbA1c) by 0.4 to 1.42.

Alternatives to Toujeo

Toujeo contains a long-acting insulin called insulin glargine. There are many opposite forms of insulin, that are personal by how quick they work or how prolonged they work. Here’s a list of a opposite kinds of insulins that are available.


Toujeo vs. other drugs

You competence consternation how Toujeo compares to other drugs that are prescribed for identical uses. Below are comparisons between Toujeo and several medications.

Toujeo vs. Tresiba

Toujeo and Tresiba are both long-acting insulin products, though they enclose opposite forms of insulin. Toujeo contains insulin glargine, and Tresiba contains insulin degludec.

Uses

Toujeo is FDA-approved to control blood sugarine levels in adults with form 1 or form 2 diabetes. Tresiba is FDA-approved to control blood sugarine in adults and children 1 year of age and comparison with form 1 or form 2 diabetes.

Drug forms and administration

Toujeo and Tresiba are both accessible as a prefilled coop that’s used to broach insulin regulating an injection underneath a skin (subcutaneous).

Side effects and risks

Toujeo and Tresiba both enclose a long-acting insulin ingredient. Therefore, a side effects that they means are really similar.

More common side effects of Toujeo and Tresiba include:

  • respiratory infections such as a common cold, flu, and bronchitis
  • low blood sugarine (hypoglycemia)
  • fluid influence with flourishing of a arms or legs
  • weight gain
  • pain, rash, swelling, and itchiness during a injection sites
  • skin thickening or pits during a injection sites

Other common side effects that have been reported in people regulating Tresiba embody headache and diarrhea.

Serious side effects that can start in people regulating Toujeo or Tresiba competence include:

  • severe low blood sugarine (hypoglycemia)
  • low potassium levels (hypokalemia)
  • severe allergic reaction

Although both Toujeo and Tresiba can means hypoglycemia, Toujeo competence have a reduce risk of this condition. In one study, Toujeo had a reduce risk of hypoglycemia than Tresiba when these drugs were initial started and dosages were being increased.

In another study, low blood sugarine levels during night were reduction common in people holding Toujeo compared to Tresiba. And in nonetheless another study, a risk of critical low blood sugarine and night low blood sugarine was reduce in people holding Toujeo compared to those holding Tresiba.

Effectiveness

Toujeo and Tresiba have been directly compared in several clinical studies. Overall, they were found to be really identical in effectiveness.

In a 2018 investigate in people with form 2 diabetes, Toujeo and Tresiba worked about equally good for dwindling hemoglobin A1c (HbA1c) after 24 weeks of treatment. Another 2018 investigate in people with form 2 diabetes also found that Toujeo and Tresiba worked about equally good for obscure blood sugarine levels. And there were identical formula in nonetheless another 2018 study.

One investigate evaluated switching people with form 2 diabetes from a long-acting insulin such as Lantus or Levemir, to Toujeo or Tresiba. In this study, creation a switch softened HbA1c about equally good in people who switched to Toujeo as people who switched to Tresiba.

Some investigate did find a disproportion between a opening of a dual drugs. A 2018 research of studies found that Toujeo competence means some-more quick blood sugarine levels via a day as compared to Tresiba.

Costs

Toujeo and Tresiba are brand-name medications. Neither drug is accessible in a general form.

Toujeo competence cost reduction than Tresiba. The tangible volume we compensate for possibly drug will count on your word plan.

Toujeo vs. Basaglar

Toujeo and Basaglar are both brand-name drugs that enclose a long-acting insulin. In fact, they enclose a same ingredient, insulin glargine. The categorical disproportion between them is that Toujeo is some-more strong than Basaglar.

Uses

Toujeo is FDA-approved to urge blood sugarine control in adults with form 1 and form 2 diabetes.

Basaglar is FDA-approved to urge blood sugarine control in adults and children with form 1 diabetes, and in adults with form 2 diabetes.

Drug forms and administration

Both Toujeo and Basaglar are delivered regulating an injection that’s given underneath a skin (subcutaneous). They’re also both customarily given once daily.

Side effects and risks

Toujeo and Basaglar enclose a same long-acting insulin ingredient, insulin glargine. Therefore, both drugs can means identical common and critical side effects.

More common side effects of Toujeo and Basaglar include:

  • respiratory infections such as a common cold, flu, or bronchitis
  • low blood sugarine (hypoglycemia)
  • fluid influence with flourishing of a arms or legs
  • weight gain
  • pain, rash, swelling, or itchiness during a injection sites
  • skin thickening or pits during a injection sites

Other common side effects that have been reported in people regulating Basaglar include:

  • joint pain
  • headache
  • high blood pressure
  • diarrhea
  • depression

Serious side effects that can start in people regulating Toujeo or Basaglar competence include:

  • severe low blood sugarine (hypoglycemia)
  • low potassium levels (hypokalemia)
  • severe allergic reaction

Other differences in side effects

Although these drugs can means mostly identical side effects, there competence be some differences.

In one study, people with form 2 diabetes were switched from Lantus to possibly Basaglar or Toujeo. After a switch, people holding Toujeo had a reduce risk of low blood sugarine levels compared to Basaglar or Lantus.

This is identical to studies comparing Toujeo and Lantus, that is biologically identical to Basaglar. In one study, Toujeo was reduction approaching to means hypoglycemia than Lantus.

Researchers in one investigate found that people holding Toujeo had reduction weight benefit than people holding Lantus. However, in another study, there was no disproportion in weight benefit between a dual drugs.

Effectiveness

Toujeo and Basaglar have been directly compared in one study. In this study, people with form 2 diabetes were switched from Lantus to possibly Basaglar or Toujeo. After a switch, both Toujeo and Basaglar worked about equally good for progressing blood sugarine control.

Toujeo has also been directly compared to Lantus, that is biologically identical to Basaglar. (Lantus and Basaglar are approaching to have a same effects.) These studies uncover that Toujeo and Lantus work about equally good for dwindling fasting blood sugarine and hemoglobin A1c (HbA1c) levels in adults with form 1 or form 2 diabetes.

One disproportion is that Toujeo competence work longer than Lantus or Basaglar. Toujeo lasts adult to 36 hours, while Lantus and Basaglar final for 20 to 24 hours. Toujeo competence also means some-more quick blood sugarine levels via a day, with fewer low or high blood sugarine events.

Costs

Toujeo and Basaglar are brand-name medications. Neither drug is accessible in a general form.

Basaglar competence cost somewhat reduction than Toujeo. The tangible volume we compensate for possibly drug will count on your word plan.

Toujeo vs. Levemir

Toujeo and Levemir are both long-acting insulin products, though they enclose opposite forms of insulin. Toujeo contains insulin glargine, and Levemir contains insulin detemir.

Uses

Toujeo is FDA-approved to control blood sugarine levels in adults with form 1 or form 2 diabetes. Levemir is FDA-approved to control blood sugarine in adults and children 2 years of age and comparison with form 1 diabetes or adults with form 2 diabetes.

Drug forms and administration

Both Toujeo and Levemir are given by an injection underneath a skin (subcutaneous). They’re also both customarily given once daily.

Side effects and risks

Toujeo and Levemir both enclose a long-acting insulin ingredient. Therefore, a side effects that they can means are really similar.

More common side effects of Toujeo and Levemir include:

  • respiratory infections such as a common cold, flu, or bronchitis
  • low blood sugarine (hypoglycemia)
  • fluid influence with flourishing of a arms or legs
  • weight gain
  • pain, rash, swelling, and itchiness during a injection sites
  • skin thickening or pits during a injection sites

Other common side effects that have been reported in people regulating Levemir include:

  • headache
  • back pain
  • fever
  • diarrhea
  • nausea
  • vomiting
  • stomach pain

Serious side effects that can start in people regulating Toujeo or Levemir competence include:

  • severe low blood sugarine (hypoglycemia)
  • low potassium levels (hypokalemia)
  • severe allergic reaction

Effectiveness

Toujeo and Levemir haven’t been directly compared in clinical studies. However, an surreptitious comparison found that Toujeo and Levemir competence work about equally good for dwindling hemoglobin A1c (HbA1c).

Costs

Toujeo and Levemir are brand-name medications. Neither drug is accessible in a general form.

Toujeo competence cost reduction than Levemir. The tangible volume we compensate for possibly drug will count on your word plan.

Toujeo vs. Trulicity

Toujeo is a long-acting insulin product that contains insulin glargine. Trulicity, that contains a drug dulaglutide, is personal as a glucagon-like peptide-1 (GLP-1) receptor agonist.

Uses

Toujeo is FDA-approved to control blood sugarine levels in adults with form 1 or form 2 diabetes.

Trulicity is FDA-approved to urge blood sugarine levels in adults with form 2 diabetes. It’s not used for people with form 1 diabetes.

Drug forms and administration

Both Toujeo and Trulicity are given by injection underneath a skin (subcutaneous). Toujeo is given once daily. Trulicity is given once weekly.

Side effects and risks

Toujeo and Trulicity have some identical side effects and some that differ. Below are examples of these side effects.

* Trulicity has a boxed warning from a FDA about this side effect. This is a strongest warning a FDA requires. A boxed warning alerts doctors and patients about drug effects that competence be dangerous.

Some people consternation how diabetes drugs will impact their weight. In studies of Toujeo, some people gained weight. In studies of Trulicity, some people mislaid weight, trimming from about 3 pounds to 5 pounds over 26 weeks.

Effectiveness

Toujeo and Trulicity haven’t been directly compared in clinical studies. This is approaching given they’re meant for people with opposite diagnosis needs.

According to diagnosis guidelines, Trulicity is deliberate a first-choice diagnosis choice for people with form 2 diabetes who can’t take metformin. And long-acting insulin, such as Toujeo, is endorsed when one or some-more other drugs, such as Trulicity or metformin, don’t reduce hemoglobin A1c (HbA1c) enough.

Costs

Toujeo and Trulicity are brand-name medications. Neither drug is accessible in a general form.

Toujeo competence cost reduction than Trulicity. The tangible volume we compensate for possibly drug will count on your word plan.

Toujeo and alcohol

Alcohol should be avoided, or consumed carefully, while holding Toujeo. Drinking ethanol can boost or diminution blood sugarine levels.

If we splash ethanol while holding Toujeo, we should guard your blood sugarine levels some-more closely.


Toujeo interactions

Toujeo can correlate with several other medications. It can also correlate with certain supplements.

Different interactions can means opposite effects. For instance, some can meddle with how good a drug works, while others can means augmenting side effects.

Toujeo and other medications

Below is a list of drugs that can correlate with Toujeo. This list doesn’t enclose all drugs that competence correlate with Toujeo.

Before holding Toujeo, be certain to tell your alloy and pharmacist about all prescription, over-the-counter, and other drugs we take. Also tell them about any vitamins, herbs, and supplements we use. Sharing this information can assistance we equivocate intensity interactions.

If we have questions about drug interactions that competence impact you, ask your alloy or pharmacist.

Drugs that boost a risk of low blood sugarine (hypoglycemia)

When taken with Toujeo, some drugs can means low blood sugarine levels and boost a risk of hypoglycemia. If we take these medications, we competence need to check your blood sugarine levels some-more often. Also, your alloy competence need to change your sip of Toujeo.

Examples of these drugs include:

  • other diabetes medications, such as:
    • dulaglutide (Trulicity)
    • linagliptin (Tradjenta)
    • liraglutide (Victoza)
    • glyburide (Glynase)
    • glimepiride (Amaryl)
    • glipizide (Glucotrol)
    • metformin (Glucophage)
    • sitagliptin (Januvia)
  • high blood vigour medications, such as:
    • benazepril (Lotensin)
    • candesartan (Atacand)
    • enalapril (Vasotec)
    • irbesartan (Avapro)
    • olmesartan (Benicar)
    • perindopril
    • quinapril (Accupril)
    • ramipril (Altace)
    • valsartan (Diovan)
  • other medications, such as:
    • disopyramide (Norpace)
    • fluoxetine (Prozac, Sarafem)
    • pentoxifylline
    • sulfamethoxazole-trimethoprim (Bactrim, Septra)

Drugs that boost your blood sugarine levels

Some drugs can boost blood sugarine levels in your body. If we take these medications, we competence need to check your blood sugarine levels some-more often. Also, your alloy competence need to change your sip of Toujeo.

Examples of these drugs include:

  • albuterol (ProAir, Proventil, Ventolin)
  • budesonide (Entocort EC, Pulmicort, Uceris)
  • clozapine (Clozaril, Fazaclo)
  • fluticasone (Arnuity, Flonase)
  • levothyroxine (Levoxyl, Synthroid, Tirosint, Unithroid)
  • mometasone (Asmanex, Elocon, Nasonex)
  • niacin (Niaspan, Slo-Niacin, others)
  • olanzapine (Zyprexa)
  • oral contraceptives (birth control pills)

Toujeo and spices and supplements

When taken with Toujeo, some spices and supplements competence boost your risk of low blood sugarine (hypoglycemia). Examples include:

  • alpha-lipoic acid
  • banaba
  • bitter melon
  • chromium
  • gymnema
  • prickly pear cactus
  • white mulberry

How to take Toujeo

You should take Toujeo according to your alloy or medical provider’s instructions.

Timing

Toujeo is taken once daily. It should be taken during about a same time any day. Your medical provider competence suggest holding it in a morning before breakfast, or in a dusk before dinner.

Taking Toujeo with food

Toujeo doesn’t need to be taken with food or during a time of a meal.

However, people with diabetes need to follow unchanging diet, exercise, and insulin schedules, that would embody diagnosis with Toujeo. These schedules competence be opposite for any person. Your medical provider can tell we more.


How Toujeo works

For people with form 1 diabetes, their bodies don’t furnish adequate insulin. People with form 2 diabetes, on a other hand, customarily have insulin resistance. This means their physique doesn’t respond to insulin a approach it should. Over time, people with form 2 diabetes competence also stop producing adequate insulin.

Toujeo helps urge blood sugarine levels in people with possibly form of diabetes.

How insulin affects blood sugar

Normally, when we eat food, your physique releases insulin to assistance ride glucose (sugar) from your bloodstream into a cells of your body. The cells afterwards spin a glucose into energy.

When your physique doesn’t furnish adequate insulin, or when your physique doesn’t respond to insulin a approach it should, this causes problems. The cells of your physique competence not get a glucose they need to work correctly.

Also, we competence get too many glucose in your blood. This is called high blood sugarine (hyperglycemia). Having too many glucose in your blood can repairs your physique and organs, including your eyes, heart, nerves, and kidneys.

What Toujeo does

Toujeo is a form of insulin called insulin glargine. It’s a long-acting insulin, that means it works for a whole day (up to 36 hours).

Toujeo is used to partly reinstate a body’s healthy prolongation of insulin, that will assistance pierce glucose into your cells. This helps your cells get a sugarine they need. It also helps stabilise your blood sugarine levels.

Toujeo is mostly used with other medications. For instance, for form 2 diabetes, it competence be used with metformin. And for form 1 diabetes, it competence be used with a form of insulin that’s taken with meals.

How prolonged does it take to work?

Toujeo doesn’t work right away. When we initial start holding a drug, it can take adult to 5 days to strech a full effect.

Toujeo storage

Toujeo SoloStar and Toujeo Max SoloStar pens should be refrigerated until we start regulating them. They shouldn’t be stored with a needle attached.

Refrigeration

Be certain to keep Toujeo SoloStar and Toujeo Max SoloStar pens in a fridge until we use them. When a pens are in use, keep them during room temperature.

The pens can stay during room heat for adult to 42 days. After a needles have been during room heat for 42 days, we shouldn’t use them. You should dispose of them during that time. And once we take a pens out of a fridge for use, don’t put them behind in a refrigerator.

Also, don’t solidify a pens. If a coop becomes frozen, don’t use it. Dispose of it.

Shelf life

Each Toujeo package has an death date. Toujeo shouldn’t be used if it has left over a death date.

Toujeo and pregnancy

There are no studies of Toujeo use during pregnancy. An research of studies of insulin glargine, a insulin contained in Toujeo, didn’t find any disastrous effects in mom or fetus when it was used during pregnancy.

If you’re profound or formulation to turn profound while holding Toujeo, speak with your alloy about a risks and benefits. Your body’s insulin mandate competence change during pregnancy. If you’ll be regulating Toujeo, your sip competence need to be opposite during your pregnancy.


Toujeo and breastfeeding

Toujeo is deliberate protected to use during breastfeeding. However, your body’s insulin mandate competence change during pregnancy. So, your alloy competence need to change your Toujeo sip while you’re breastfeeding.

Be certain to speak to your alloy initial if we wish to breastfeed while holding Toujeo.


Common questions about Toujeo

Here are answers to some frequently asked questions about Toujeo.

Is Toujeo a same thing as Lantus?

No. Toujeo isn’t a same as Lantus, though they’re really similar. Both Toujeo and Lantus enclose a same long-acting insulin, insulin glargine. But Toujeo contains 300 units per mL of solution, while Lantus contains 100 units per mL of solution.

Toujeo is some-more strong than Lantus.

Is Toujeo a fast-acting insulin?

No, Toujeo isn’t fast-acting. It has a delayed onset. When we initial start holding Toujeo, it can take adult to 5 days to take full outcome on your blood sugarine levels.

But Toujeo is long-acting. It can work for adult to 36 hours in your body.

When does Toujeo peak?

Toujeo, like other long-acting insulins, doesn’t have a peak. It mimics a body’s healthy solid recover of insulin via a day.

Can we brew Toujeo with other insulins?

No. Toujeo shouldn’t be churned with other insulins.

How do we switch from another form of insulin to Toujeo?

This depends on a other form of insulin that you’re taking. Talk with your medical provider about a best approach to switch.

Usually, when switching from another once-daily, long-acting insulin to Toujeo, a starting sip of Toujeo is a same as a sip for a other long-acting insulin. If needed, your medical provider will work with we to adjust your sip of Toujeo after your switch.

However, many people who switch from Lantus to Toujeo need a aloft daily sip of Toujeo than Lantus. This is substantially given your physique absorbs Toujeo some-more solemnly than it absorbs Lantus.

When switching from twice-daily NPH insulin, a standard Toujeo starting sip is 80 percent of a sum daily NPH insulin dose. Your medical provider will adjust your sip of Toujeo if needed.

Toujeo browns when we inject it — am we doing something wrong?

When injecting Toujeo, it’s common to feel a tiny volume of pain, such as a serious or blazing sensation.

One approach to diminution this annoy is to take your Toujeo coop out of a fridge during slightest one hour before giving an injection. The injection hurts some-more when a resolution is cold.

Toujeo overdose

Taking too many of this remedy can boost your risk of critical side effects.

Overdose symptoms

Symptoms of an overdose of Toujeo can include:

  • fatigue
  • hunger
  • dizziness
  • sweating
  • shaking
  • blurry vision
  • confusion
  • headache
  • irritability
  • loss of alertness and coma
  • fatigue
  • muscle cramps
  • weakness
  • rapid heartbeat
  • pounding chest
  • heart arrhythmia

What to do in box of an overdose

If we consider you’ve taken too many of this drug, call your alloy or find superintendence from a American Association of Poison Control Centers during 800-222-1222 or by their online tool. But if your symptoms are severe, call 911 or go to a nearest puncture room right away.

Toujeo warnings

Before holding Toujeo, speak with your alloy about any medical conditions we have. Toujeo competence not be right for we if we have certain medical conditions. Examples of these conditions include:

  • Kidney or liver disease: People with these conditions have a aloft risk of low blood sugarine levels (hypoglycemia) while holding Toujeo. If we have kidney or liver disease, speak with your alloy about stairs we can take to forestall low blood sugarine levels.
  • Heart failure: Taking Toujeo along with certain diabetes drugs called thiazolidinediones, such as Actos or Avandia, can wear symptoms of heart failure. If we have heart disaster and your symptoms get worse, speak with your doctor. You competence need to stop holding thiazolidinediones.

Toujeo expiration

Each Toujeo package has an death date listed on a label. Don’t use Toujeo if a death date listed on a tag has passed.

Toujeo SoloStar and Toujeo Max SoloStar pens also shouldn’t be used if they’ve been kept during room heat for some-more than 42 days.

The pens should be refrigerated until we start regulating them. During use, they should be left during room temperature. The pens can stay during room heat for adult to 42 days.

Once we take a pens out of a fridge for use, don’t put them behind in a refrigerator.


Professional information for Toujeo

The following information is supposing for clinicians and other medical professionals.

Mechanism of action

Toujeo contains insulin glargine U-300. Insulin glargine is a long-acting, or basal, insulin. Insulin glargine, like other insulins, lowers blood glucose by augmenting marginal glucose uptake and dwindling glucose prolongation in a liver. It also inhibits a relapse of glucose, fat, and proteins.

The insulin glargine U-300 conflict of movement occurs over a generation of 6 hours and has a generation of movement of about 36 hours.

Pharmacokinetics and metabolism

The median time to limit insulin thoroughness following subcutaneous injection of Toujeo is 12 hours. Steady state thoroughness occurs within 5 days.

Contraindications

Toujeo should not be used by people who are allergic to insulin glargine or excipients of Toujeo.

Toujeo should not be used during episodes of hypoglycemia.

Storage

Toujeo SoloStar and Toujeo Max SoloStar pens can be refrigerated though should not be frozen. Frozen pens contingency be discarded.

Once Toujeo is taken out of a fridge for use, it should not be placed behind in a refrigerator. Toujeo competence be stored during room heat for adult to 42 days. After 42 days during room temperature, Toujeo pens contingency be discarded.

Toujeo should not be stored with a needle attached.

Disclaimer: MedicalNewsToday has done any bid to make certain that all information is factually correct, comprehensive, and up-to-date. However, this essay should not be used as a surrogate for a believe and imagination of a protected medical professional. You should always deliberate your alloy or other medical veteran before holding any medication. The drug information contained herein is theme to change and is not dictated to cover all probable uses, directions, precautions, warnings, drug interactions, allergic reactions, or inauspicious effects. The deficiency of warnings or other information for a given drug does not prove that a drug or drug multiple is safe, effective, or suitable for all patients or all specific uses.



This post first appeared on Fitbody Health, please read the originial post: here

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Toujeo (insulin glargine)

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