ABSTRACT

Women are such dedicated creatures. Always busy taking care of someone. Firstly a mother takes care of her daughter and teaches her the same thing, then a daughter takes care of her whole family, understanding their wants and needs. Then she takes care of someone else's family and someone's son, whom she accepts as a husband, then her own children. But between this all she is ignoring something which is very precious to each and every being on this earth and that is her health. She ignores her urges, she tolerates the talks, she forgets her pain and finally develops the undesirable. The undesirable can be anything, it might be mental, it might be physical or both. Such undesirables are because of the lifestyle that a female is forced to follow by circumstances or may by her own will or laziness but conclusion remains the same, "Development of lifestyle disorders". One of such lifestyle disorders is PCOS or Polycystic Ovarian Syndrome. In this article we will discuss the same and also discuss the raised CRP levels associated with this condition.

INTRODUCTION

Firstly, discussing Polycystic Ovarian Syndrome or PCOS, as mentioned above, it's a lifestyle disorder and like other lifestyle disorders it can have a massive impact on the body of a Female. PCOS is a hormonal disorder that affects women of reproductive age and is characterised by the presence of multiple cysts in either one ovary or in both of the ovaries. These cysts are the result of inability to ovulate due lack of hormones and these cysts are responsible for releasing androgens in the body causing symptoms like unwanted hair growth on chest, neck, chin and back region. These high levels of androgens also results in lowering the already depleting capacity to ovulate thus enhances chances to develop infertility in future. Also, in addition this condition is also responsible for High levels of CRP in the body. CRP is C- reactive protein and is a type of protein that is produced by the liver in response to inflammation in the body. The high levels of CRP in the body along with PCOS is suggestive of risk for Cardiovascular disease.

SIGNS AND SYMPTOMS OF PCOS - POLYCYSTIC OVARIAN SYNDROME

The common signs of Polycystic Ovarian Syndrome are as follows:

• Abnormal Hair growth: The excess of facial hair growth is seen. It is known as hirsutism. This might affect other parts of the body as well. It affects almost 70% of females suffering from Polycystic ovarian syndrome.
• Acne: With polycystic ovarian syndrome acne problem is purely associated. Acne over face especially on checks, chin and forehead is noticed along with many other parts of the body.
• Baldness: Male pattern of baldness or thinning of hairs is seen.
• Small pieces of excess skin over neck and armpits. These are called skin tags.
• Dark and thick skin patches on the back of neck, in the armpits and under breasts

Symptoms regarding the Polycystic Ovarian Syndrome:

• Irregular Periods: Abnormal menstruation or missed periods is the most common sign of Polycystic ovarian syndrome.
• Abnormal Bleeding: The abnormal bleeding can include scanty bleeding or heavy bleeding during periods. Bleeding between two consecutive cycles may also be noticed.
• Not able to conceive even after a long time of trying (Suggestive of secondary infertility)
• Weight Gain: Which is especially around the belly or abdomen.

On ultrasonography enlarged ovaries are noticed because of multiple cyst formation and blood tests are usually suggestive of high levels of androgens. High glucose levels may also be seen.

Now let's discuss the most important part of this article and that is the link between High C- reactive protein and Poly cystic ovarian syndrome.

C- REACTIVE PROTEIN (CRP) AND POLY CYSTIC OVARIAN SYNDROME (PCOS)

As mentioned before C- reactive protein is an inflammatory marker in the body that is released from the liver. The elevation of CRP in PCOS is because of the inflammatory cytokines such as interleukin- 6 and interleukin -18 along with increase in the levels of leukocytes count. This is because of the low grade chronic inflammation in polycystic ovarian syndrome.

The elevated levels of C- reactive protein is suggestive of risk for Cardiovascular disease. The chances of or risk of cardiovascular disease increases with increase in atherosclerosis. Atherosclerosis is laying down of cholesterol in the artery causing buildup of plaque. Atherosclerosis is mostly related to obesity. Obesity results in altered blood glucose levels, high blood pressure, abnormal lipid profile and systemic inflammation as well.

AYURVEDA AND POLYCYSTIC OVARIAN SYNDROME

Ayurveda has suggested Polycystic ovarian syndrome and other lifestyle disorders as something which is because of the vitiation of doshas. In lifestyle disorders the first and foremost disturbance is seen in Agni or digestion power. When the digestion disturbed it causes products of ama, understood as endotoxins in modern language. These endotoxins then coagulate the srotas or microchannels. These srotas or microchannels are required in the body for free flow of vata dosha along with bodily fluids and when they get clogged, firstly vitiation of vata dosha or kinetic energy takes place which then vitiates kapha and pitta as well. The cycle of polycystic ovarian syndrome can be understood as follows:

• Due to vitiation of tridosha severe abnormalities in the menstrual cycle of a female is observed. This results in untimely bleeding, excessive, scanty or no per vaginal bleeding.
• The vitiation of doshas result in hormonal imbalance as initially there is involvement of vata dosha.
• Then due to hormonal imbalance and vitiated vata dosha, kapha dosha gets involved thus resulting in formation of cysts in the ovary or ovaries.
• The cyst then releases androgens like testosterone that increases the heat in the body as testosterone is an anabolic steroid and is responsible for regulating body temperature and male features as well. This results in excessive heat production in the body, excessive hair growth on the body, too much sweating and many other symptoms related to Polycystic ovarian syndrome. 
• Blocked channels and menstrual irregularities keep on vitiating the already vitiated doshas and then slowly results in obesity.
• Obesity then, as mentioned above is responible for high chances for altering C-reactive protein values thus suggests the risk of cardiovascular diseases.

The Nidan or causative factors in this case of PCOS are very common like deranged sleep patterns, faulty eating habits, not working out, stress etc. In short, this happens when someone usually refuses to take care of themselves. Maybe the aforementioned sentence pinches at heart but deep inside we know where we are wrong and what is to be corrected.

Now if we discuss the Ayurveda treatment for the same, then there are many herbs which can be used in this conditions are as follows:

First and foremost thing is to correct ourselves. If we don't then things can never get better. Better things to opt for are healthy food, home made meals, preferring proper meals over junk food, exercise (you need to do hard work to get better) and take time to understand things instead of instantly stressing yourself.

Secondly herbs like kanchnaar, guggul, Arjun, Lodhra, shatavari, Ashok, brahmi, jatamansi, yashtimadhu, ashwagandha etc will help in this condition impressively. Moreover, minerals like Abhrak, tankan, Loha, mandur etc also give impressive results in case of PCOS. With such herbs and minerals, herbal, herbo mineral and mineral formulations are prepared which result in PCOS along with the alterations in lifestyle and diet style.

HERBAL FORMULATIONS FOR MANAGING HIGH C-REACTIVE PROTEIN IN POLYCYSTIC OVARIAN SYNDROME BY PLANET AYURVEDA

Planet Ayurveda is a herbal products manufacturing company. It is making both Ayurveda classical products as well as its patent products. The company has been in the market for the last 20 years and the products give benefits in various conditions including PCOS and high CRP levels as well. The formulations manufactured or prepared by the company are totally herbal and don't have any side effects. These products don't have any type of adulterants, fillers, additives, flavouring agents etc. and are prepared with the methods foretold in the Ayurveda classics. For High CRP in PCOS following are the formulations which are offered by Planet Ayurveda:

PRODUCTS LIST

1. KANCHNAAR GUGGUL
2. CHANDRAPRABHA VATI
3. PUNARNAVA MANDUR
4. PRADRANTAK CHURNA
5. KUMARI SAAR
6. VRIDDHIVADHIKA VATI
7. ARJUNA CAPSULES
8. GUGGUL CAPSULES

Herbal Remedies For Managing High C-Reactive Protein In PCOS

PRODUCTS DESCRIPTION

1. Kanchnaar Guggul

Kanchnaar guggul is a classical preparation which has kanchnaar (Bauhinia variegata), guggul (Commiphora mukul), cinnamon (Cinnamomum verum), Tejpatra (Cinnamomum tamala) and many others. The formulation has a very impressive impact in various types of conditions especially related to over growths. In this case also cyst formation is a sign of overgrowth. That's why kanchnaar guggul is helpful in this case. In addition, this formulation helps in the pacification of vata and kapha dosha as well. The ingredients of this formulation are having antioxidant effects and thus give impressive results. Kanchnaar guggul is the first thing prescribed to Polycystic ovarian syndrome patients.

Dosage - Two tablets twice a day with lukewarm water after meals.

2. Chandraprabha Vati

Chanderprabha vati is also a classical preparation and is quite famous for its multiple effects on the body. The name of the formulation suggests Chandra which is the moon and prabha which is translated as glow. This formulation has ingredients like Shilajit (Asphaltum), Guggul (Commiphora mukul), sharkara (Sugar), karpoor (Cinnamomum camphora), vacha (Acorus calamus), Mustak (Cyperus rotundus) and many others. Chanderprabha vati helps in getting moon glow like effect on the body. But more than that it helps in cleansing the entire reproductive system of the female, strengthens the uterus, nourishes the body, helps in cutting down extra fat, helps in urinary tract infections, deals with high blood glucose and also has an impact on inflammation in the body. Thus gives results in lowering raised CRP values.

Dosage - Two tablets twice a day with lukewarm water after meals .

3. Punarnava Mandur

The Punarnava Mandur is also a Classical formulation. As the name of the formulation suggests, it has two for sure ingredients and that are punarnava (Boerhavia diffusa) and mandur (Ferric oxide calx). Other than these two there are more ingredients like Amalaki (Emblica officinalis), haritaki (Terminalia chebula), Haridra (Curcuma longa) and many others. This formulation acts as a source of iron and also helps in PCOS associated with hypothyroidism. Due to the presence of mandur this formulation also gives uterus cleansing effect. It helps in providing energy to the body and also helps with the symptoms of polycystic ovarian syndrome.

Dosage - Two tablet twice a day with lukewarm water after meals.

4. Pradrantak Churna

Pradrantak Churna is a patent herbal formulation which is used in the conditions related to female reproductive health. The formulation has ingredients like lodhra (Symplocos racemosa), ashoka (Saraca indica), udumbur (Ficus glomerata) and arjuna (Terminalia arjuna). The combination in this formulation helps with the irregularities of the menstrual cycle. This churna helps in cleansing the entire uterus and also opens the blocked microchannels as well. In addition, this formulation has a fantastic effect in supporting the entire female reproductive system. This formulation is the modification of classics mentioned in pushyanug churna. Pradrantak churna along with other medication helps in poly cystic ovarian syndrome very well.

Dosage - One tsp twice a day with lukewarm water after meals.

5. Kumari Saar

Kumari saar is also a patent formulation prepared by Planet Ayurveda. This formulation has only one ingredient and that is Ghrit-kumari (Aloe barbadensis). Kumari saar has an effect in betterment of digestion and also has its effect on the menstrual cycle. It is a natural antioxidant and plays a good role in many symptoms related to Polycystic ovarian syndrome. Overall this herbal juice improves digestion, strengthens the intestine, cleanses Gastrointestinal tract, increases the secretion of digestive bile, forms ahara rasa, increases physical strength and regulates the formation of all blood components. Due to such effects it enhances the entire metabolism and thus cleanses the blocked micro channels.

Dosage: Two tsp twice a day with lukewarm water after meals.

6. Vriddhivadhika Vati

Vriddhivadhika vati is a classical preparation which has many mineral ingredients. The formulation has ingredients like Shuddha parada (Purified Mercury), Shuddha gandhak (Purified Sulphur), Loha bhasma (Iron calx), Vanga bhasma (Tin calx), Tamra bhasma (Copper calx), Kansya bhasma (Bronze calx), Shuddha hartal (Purified arsenic), Shuddha tutha (Purified copper sulphate), Shankh bhasma (Pearl calx) and many others. The formulation helps in pacification of vata and kapha dosha. It also helps in the enhancement of the immune system and thus helps with various types of inflammations as well. This formulation is explained in rasashastra in Ayurveda, thus the formulation contains ingredients which can travel through microchannels and also can help in the cleansing of the same. Due to these impressive ingredients it can help in any type of overgrowth in the body. It is not having its impact on overgrowth only but also has its impact on the strengthening of various systems of the body including the reproductive system as well.

Dosage: One tablet twice a day with lukewarm water after meals.

7. Arjuna Capsules

Arjun capsules are one of the best potent herbal formulations. The capsules have standardised extract of only arjun (Terminalia arjuna). As the high C-reactive protein is related to the risk of developing cardiovascular diseases thus arjun plays a very important role here. It helps in keeping the heart health intact and while other medications have their effect in lowering the inflammation and thus stabilising c-reactive protein. Arjun capsules support the musculature of the heart, have the effect on its pumping and also help with anxiety or palpitations which may be present in the patient. In addition, arjuna is famous for its healing effect on the entire body.

Dosage: Two capsules twice a day with lukewarm water after meals.

8. Guggul Capsules

The Guggul capsules are the patent product of Planet ayurveda. The capsules have guggul (Commiphora guggul) as its only ingredient. The guggul capsules are very effective when it comes to opening the blocked channels. Due to the hot potency of guggul the toxins in the micro channels are melted and digested away. In addition, it also helps in reducing inflammation in the body and reduces risk of cardiovascular disease in this case. Guggul is very well known to regulate menses as well and is a very good agent when it comes to weight loss. Guggul also helps in managing high blood sugar in this case.

Dosage: One capsule twice a day with lukewarm water after meals.

CONCLUSION

Polycystic ovarian syndrome is a lifestyle disorder which has become very common in Females, in India and abroad. A female of reproductive age, ageing between 13-42 years can develop these conditions and thus suffers a lot. Sometimes this condition causes obesity, sometimes obesity causes this condition but the initiation in both of the cases remains the same and that is blocking of microchannels due to production of endotoxins. These endotoxins not only cause one thing but can cause a lot of troubles which might cause one after the other disturbance of the body. That's why it is mentioned in Ayurveda that taking care of "Agni" or "Digestive Power" is equal to taking care of your entire body. In case of any query kindly visit www.PlanetAyurveda.com