Should You Use Toremifene?

Before using Toremifene one should check a few factors to stay away from any complication that may arise due to the use of the Drug. Here are a few factors that you should check before taking the drug :

• Allergic: The first and the foremost thing that you should check is if you are allergic to toremifene.
• Heart Condition: One should even regularly check their heart condition especially if they suffer from any form of QT syndrome. It has been noticed over time that toremifene can itself cause heartbeat irregularities such as QT prolongation which can even turn into a very serious condition called torsades de pointes. The condition causes seizures in a person and even frequent fainting.
• Mineral Level In Blood: It is not advisable for a person with low magnesium and potassium levels to use the drug.
• Medication: One should avoid taking toremifene if they regularly use clozapine, ondansetron or even quetiapine.

Prior To Using Toremifene :

This drug can trigger multiple medical conditions in a person and it is absolutely essential to discuss the issues with a doctor or a pharmacist before using the drug. Here is a list of medical conditions that interact with it.

• Pregnancy: Though a woman after her menopause normally does not get pregnant it is important to know that toremifene is harmful for an unborn baby developing in the womb. Someone who is pregnant or might become pregnant should avoid taking the medicine. Although it is still not clear if the drug is passed on to breast milk in breastfeeding mothers it is not advisable to take the medicine if one breastfeeds her kid.
• Medication: A person who is under any prescription drug or even nonprescription drugs like herbal medicine or supplements should contact a doctor about the issue before using toremifene.
• Allergy: A person who is allergic to medicines should ask his doctor if it is safe for him to use the drug.
• Bone Cancer: Though toremifene is used to treat a type of cancer, people with bone cancer or excessive growth endometrium should avoid taking the drug.
• Blood Clots: A person with a history of blood clots should avoid taking the medicine.

Organ Problems: A person who has a history of disturbances in the heart and liver should refrain from taking the Medicine. People having blood electrolyte problems should also stay away from this drug..

Apart from the medical conditions, there are several medicines that interact with toremifene to cause fatal problems in the user. The medicines mentioned bellow causes irregularities in the heart and cause serious risks and thus should be avoided

Antiarrhythmics such as amiodarone, dofetilide, sotalol are all reactive with the drug.

• Medicines like arsenic, astemizole, cisapride, clozapine, dolasetron, domperidone, halofantrine, haloperidol
• Medicines like romidepsin, tacrolimus, terfenadine, tetrabenazine
• Macrolide antibiotics such as clarithromycin and erythromycin
• Medicines containing chemicals like maprotiline, methadone, nilotinib, ondansetron paliperidone, pentamidine, phenothiazines, pimozide, quetiapine
• Quinolone antibiotics such as levofloxacin and ofloxacin
• Tricyclic antidepressants like amitriptyline
• Tyrosine kinase inhibitors like dasatinib
• Medicines like vandetanib, vemurafenib, venlafaxine and ziprasidone.

2. Fluorouracil is dangerous as it reacts with the drug to causes disturbances in the stomach.

3. There are medicines like Azole antifungals, some of which are itraconazole, ketoconazole, nefazodone which increases the level of side effects caused by toremifene. Mitomycin C, nefazodone, protease inhibitors such as boceprevir and ritonavir also interact with toremifene to increase the side effects of toremifene.

4. Medicines containing strong chemicals such as carbamazepine, dexamethasone, rifamycins such as rifabutin and rifampin can decrease the effects of the drug and should not be taken while one is using the drug.

5. Hydantoins such as phenytoin and anticoagulants such as warfarin should not be taken along with toremifene as these drugs increase the side effects caused by the drug.

As there are more drugs that react with the drug, a person should discuss the issue with a doctor ao pharmacist before taking the drug.

How Should You Take Toremifene?

While it can be taken both with and without food it is not advisable to have grapefruit while being under the drug. One has to particularly careful while taking the drug, and in case one misses a dose they should go back to the missed dose and start over rather than taking two doses together.

Facts You Should Know About Toremifene :

1. Some users experience dizziness and vision problems while using toremifene and the results are even more severe when the drug is taken with alcohol or medicines which interact with the drug. The drug should be used very carefully, and it is advisable to avoid much motion till one is sure about the effects and how to deal with it.

2. One should contact a doctor or a pharmacist and ask for ways to minimize any effects of nausea that the drug might have.

3. Toremifene is only recommended for women who have passed their menopause. In case you are still young, make sure you don’t get pregnant while using the drug.

4. Regular tests to indicate blood cell count, blood electrolytes, liver function should be performed while using the drug to gauge the progress and check the side effects. Electrocardiograms are also recommended.

5. Toremifene should be kept away from the reach of children and it is not at all recommended for them.

6. The issue with pregnancy is, it has been noticed that toremifene causes harm to the fetus. It is very important to discuss the issues like pros and cons of using the drug during pregnancy with a doctor one trusts. As mentioned it is still known it the drug can make it’s way to a baby through the breastmilk but it is recommended for a breastfeeding mother to avoid this drug as it is very dangerous to a baby. Thus this is also an issue that one should discuss with their doctors.

Dosage 

It is very important to follow the instructions as suggested by the prescription. One should not experiment with the quantity recommended. The medicine can be taken with food as well as without it and it should be taken at the same time every single day.

While using the drug one needs to have regular blood tests and even needs to check his liver functions. The drug should be stored at room temperature and kept away from moisture and heat.

As already mentioned, in case someone misses out on their dose they should start again from the next scheduled dose. One should never take two doses at the same time to make up for a missed dose.

Side Effects

If you ever notice symptoms like allergic reactions, breathing problems, hives, swelling of lips, face or tongue, you should immediately get in contact with your doctor. The drug is known to cause irregular rhythm changes and if you notice such changes you should stop using the drug and get in touch with your doctor as the condition can turn out to be fatal. These are a few symptoms that one should look for:

• Chest pain accompanied by a headache and dizziness
• Convulsions
• Very fast heartbeats
• Slow heart rate
• Weak pulse
• Blurred vision
• Shoulder pain
• Nausea
• Sweating
• Heart attack symptoms like chest pain, dizziness etc
• Symptoms of stroke-like numbness, weakness, lack of energy etc
• Symptoms of clots in the lungs like chest pain, dry cough, fast breathing and blood coughs.

Other side effects include:

• Sweating, flashes of heat.
• Nausea
• Swelling
• Abnormal liver condition.

Overdose :

You should immediately get in contact with the American Association of Poison Control Center or a local poison control center if you ever sense an overdose. Symptoms include dizziness, hallucinations, hot flashes, loss of coordination, vomiting, vaginal bleeding and nausea.

The contact number of the American Association of Poison Control Center is 1-800-222-1222.

Interactions :

Some food items like grapefruit react with toremifene and can result in undesired results. One should be careful while using the drug and be sure to avoid grapefruit or grapefruit juice.

As the drug normally passes into the user’s body fluid like urine, vomit etc. So any person getting in contact should use rubber gloves while handling.

Additional instructions :

You should discuss any query they have about the drug with their doctors or pharmacists to be safe and secure. A user should never share their dose with anyone, and use it themselves. If you notice less progress you should ask your doctor about it. The unused medicines should not be disposed carelessly, and advice should be taken. Apart from keeping the drugs away from kids, one should also make sure that he takes the drug as mentioned, the user should not experiment with the doses.

Toremifene & Body Builders 

Though Fareston or toremifene citrate, commonly known as toremifene among bodybuilders, is an FDA approved the drug to treat breast cancer it is highly popular among bodybuilders for it’s effectiveness in treating gynecomastia or bitch tits.  The drug is still new to everyone, the majority of bodybuilders are confused about it and the drug surely has some drawbacks.

Fareston Vs SERMs :

While a bodybuilder is under the use of steroids, their FH and LH count drops to a minimum level which results in a dormant pituitary gland and thus the testosterone secretion stops. This suppression is normal during any anabolic steroid cycle.

To revive the dormant pituitary gland a post cycle therapy (PCT) is generally required. Drugs called SERMs are used to prevent the flow of estrogen to the pituitary, this raises the LH levels and testosterone levels. Though the effect is temporary, it boosts the revival of the pituitary and even helps to get the testosterone levels back to normal.

An important factor behind the use of Fareston among bodybuilders is its anti-gyno characteristics. According to doctors and researchers, about three-fifths of the breast cancer cells show apoptosis on treatment with the drug. Thus it is believed that someone suffering from gynecomastia can benefit from this drug. It is even believed that apart from removing the present gyno it will also prevent it from growing.

Though there are benefits, the use of the drug citrate of forest on is still limited in the spheres of bodybuilding due to the side effects that the drug can have and even for the fact that it is new in the market. Apart from these, there is one more reason for its limited use, some evidence hint that this drug can harm free testosterone levels.

SHBG 

As per studies conducted in the medical world, forest on raises SHBG levels which results in a decrease in free testosterone levels. Sex Hormone Binding Globulin (SHBG) is generally a protein that clings to sex steroids and makes them dormant. Testosterone is mainly of two types, free testosterone and bound testosterone. A person uses free testosterone and thus the more free testosterone percentage he has in the total testosterone level, the better it is. The fact that toremifene citrate raises SHBG makes it inferior to SERMs like tamoxifen citrate.

IGF-1 & SERMs

A significant anabolic hormone in the body is IGF-1 and it assists the bodybuilders in developing muscles. While SERMs like Nolvadex interacts with IGF-1 and decreases it’s levels while the athlete is under it’s use. Fareston does not interfere with IGF-1 and thus in this regard, Fareston is better that SERMs.

Side Effects For Bodybuilders

Though the side effects arising from toremifene citrate or forest on among bodybuilders is quite less one can develop a few, here are some of them :

• Nausea
• Sweating
• Eyesight problems
• Dryness in eyes
• Frequent mood swings
• Rash
• Swelling of limbs

How Should Bodybuilder Take Fareston?

A bodybuilder should start with a dosage of forty milligrams to sixty milligrams every day. If the purpose of use is to fight existing bitch tits one should use double of the recommended dosage and add an aromatase inhibitor Aromasin with the drug. During PCT builders normally take a dosage of eighty milligrams to hundred milligrams each day

Half-Life: The half-life of the drug citrate is five days which is similar to other drugs as Clomid and Nolvadex

A bodybuilder should gather enough information and have adequate discussions with his doctor and trainer before taking the drug.

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