What Body System Is The Spleen In – The Spleen is under the rib cage. It helps remove unhealthy, old, and deformed red blood cells from the circulation. Nerthuz/iStock/Thinkstock

The spleen helps keep harmful microorganisms out of the bloodstream. Contains important components of the body’s immune system The spleen also removes unhealthy, old, and misshapen red blood cells from the circulation.

What Body System Is The Spleen In

Red blood cells carry oxygen throughout the body and remove carbon dioxide (waste). These disc-shaped cells are filtered by the spleen based on their physical characteristics. They can reenter the bloodstream only through tiny splenic structures called interstitial slits, when the size, shape, or deformability of red blood cells changes. will not be able to pass

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Under certain conditions, such as hereditary spherocytosis Abnormally shaped red blood cells may become stuck in the spleen. Causes anemia. In addition, some diseases such as malaria and leukemia. and lymphoma May cause the spleen to enlarge. and leads to filtering not only abnormal cells but also healthy red blood cells.

Studying how the human spleen filters abnormal red blood cells is challenging. The anatomy and physiology of the human spleen differs from that of conventional animal models. and invasive procedures such as biopsies or needle aspiration. It can cause dangerous bleeding. A team of researchers led by Dr. Subra Suresh from Carnegie Mellon University and Dr. Ming Dao from MIT approached this problem using computational simulation tools. Their work was funded in part by the National Heart, Lung, and Blood Institute (NHLBI). The study is published online in

The team developed a computer model of the mechanics of red blood cells as they move through the spleen. The researchers determined that the cells were significantly deformed as they moved through the splenic lacunae. This is in contrast to the bullet-shaped changes that occur in narrow capillaries.

The analysis reveals the limits of surface area and volume that red blood cells can pass through the spleen. This research shows how the splenic incision determines the size and shape of the distribution of healthy red blood cells. The team’s predictions are consistent with results from independent experiments using healthy, artificially modified, and infected human red blood cells.

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“The computational model and analysis from this work along with a variety of experimental observations. It points to a more detailed picture of how human splenic physiology is likely to influence several important geometric characteristics of red blood cells,” Suresh said.

“We have presented results showing that the spleen is the main organ that determines the shape of circulating red blood cells,” Dao added.

This work may lead to a better understanding of the spleen’s role in various diseases. These findings may have implications for future treatment guidelines.

Reference: Biomechanics of red blood cells in the human spleen and its implications for physiology and disease Pivkin IV, Peng Z, Karniadakis GE, Buffet PA, Dao M, Suresh S.

Ill Spleen Color Icon Sore Human Organ People Disease Unhealthy Lymphatic System Sick Internal Body Part Immune System Isolated Vector Illustration Stock Illustration

Funding: National Heart, Lung, and Blood Institute (NHLBI); National Science Foundation United States Department of Energy; Swiss platform for advanced scientific computing and the Singapore-MIT Alliance for Research and Technology.

Research Matters is a weekly, peer-reviewed update of research highlights published by the Director’s Office of Communications and Public Liaison. The spleen filters your blood and also stores red blood cells, platelets, and white blood cells. But if your spleen is removed, other parts of the lymphatic system can take over these functions.

The spleen is part of your body’s lymphatic system. The lymphatic system helps remove waste from cells. maintain fluid balance and creates and stimulates the activity of white blood cells that fight infection for the immune system.

It has been shown that the spleen also produces substances that play important roles in inflammation and healing.

Healthy Spleen Color Icon. Human Organ In Good Health. People Wellness. Functioning Lymphatic System. Internal Body Part In Good Shape. Wholesome Immune System. Isolated Vector Illustration 4664896 Vector Art At Vecteezy

The spleen is located in the upper left side of the abdomen. It is behind the ribs, under the diaphragm, and above and behind the stomach.

In healthy individuals They can become significantly larger when a person is sick or injured. Your spleen is involved in your body’s immune response. and in recycling old blood cells

The number of red blood cells that carry oxygen throughout your body. and the number of platelets, which are cells that help blood clot. By destroying and removing abnormal, old, or damaged cells.

The spleen plays an important role in your immune response. When bacteria, viruses, or other germs are detected in the blood, they produce white blood cells called lymphocytes. To fight infections caused by these things

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The spleen is located in the upper left side of the abdomen. It can be found next to the abdomen and behind the left ribcage.

Many conditions can cause the spleen to become enlarged. Especially diseases that cause blood cells to break down too quickly, for example by destroying too many blood cells. It can cause the spleen to work too hard. and make it bigger

When your spleen is enlarged It cannot filter the blood as efficiently as before. Normal red blood cells and platelets may be accidentally filtered out. As a result, there are fewer healthy blood cells in the body.

The above shows that an enlarged spleen leads to the destruction of too many blood cells, a condition known as hypersplenomegaly.

Spleen: Anatomy, Location And Functions

An enlarged spleen may not cause symptoms at first. It can eventually become painful. If your spleen is too enlarged The spleen can rupture. The spleen may be injured or ruptured immediately after a severe blow to the abdomen. broken ribs or other accidents This can lead to the spleen being removed.

Some spleen concerns, such as an enlarged spleen, can be detected through a physical exam by your doctor.

Blood tests can also be used to evaluate your liver function or to check if you have high white blood cells in your body. This may indicate an infection.

A magnetic resonance imaging (MRI) scan can also detect tumors and cysts. Or it can be used to track blood flow through the spleen.

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It is difficult to protect the health of the spleen. Although there are many causes of an enlarged spleen, such as cancer or blood cell disorders, it may be unavoidable. But the UK’s National Health Service says there are many treatment options available for other concerns. About the spleen include:

There are several ways to prevent an enlarged spleen, such as avoiding infections or injuries that can damage the spleen. Here are a few tips to try your best:

If you have an enlarged spleen Consider following the treatment plan your doctor recommends. Try to avoid contact sports and other high-impact activities. until your doctor recovers

The National Health Service says you can live without a spleen. It is an important but not necessary organ. If damaged by disease or injury It can be removed without being life-threatening. Surgery to remove the spleen is called a splenectomy.

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Your lymph nodes and liver can perform many of the important functions of your spleen. However, without your spleen The above organizations also say that you are more likely to contract certain infections. And if you’re sick It may take longer than usual to recover.

They say it depends on your age and overall health. Your doctor may recommend that you receive these vaccines:

Even though your spleen isn’t a large organ, But it plays an important role in your body. Helps remove old, damaged blood cells. and produce cells that fight infection to protect your health. The spleen also produces certain substances that play important roles in inflammation and healing.

Infections and injuries can damage your spleen and cause it to enlarge or rupture. If the damage is widespread You may need surgery to remove your spleen. You can live a normal, healthy life without having a spleen. But you’ll need to take extra precautions to prevent infection.

The Location Of The Spleen In The Female Body, The Human Digestive System Stock Vector

It has strict recruitment guidelines and relies on peer-reviewed studies. Academic research institute and medical associations We avoid using tertiary references. You can learn more about how we ensure our content is accurate and up-to-date by reading our editorial policy.

Our experts are constantly monitoring your health and wellness. And we update our article as new information becomes available. in multicellular organisms An organ is a group of tissues that come together as a structural unit to perform a common function.

In the hierarchy of life Organs are located between tissues and organ systems. Tissues are made from the same type of cells to perform a common function. Different types of tissue They form organs that have specific functions. For example, the intestinal wall is made up of epithelial tissue and smooth muscle tissue.

Two or more organs work together to perform one bodily function. causing organ systems Also known as biological systems or body systems.

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Organ tissues can be broadly classified into parka, functional tissue, and stroma, which is structural tissue that has a supportive, connective, or auxiliary function. For example, the tissue of hormone-producing glands is parka. while the stroma includes the nerves that supply the parchyma with energy. Blood vessels that oxygenate and nourish it and carry away its metabolic waste. and connective tissue that provides

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