M.Pharm II Semester Regular & Supplementary Examinations, September 2015
NOVEL DRUG DELIVERY SYSTEMS II
(Pharmaceutics)
Max Marks: 60 Time: 3 hours
Answer any FIVE questions
All questions carry equal marks
All questions carry equal marks
1. (a) Explain epithelia cell Junction structure.
(b) Write the role epithelia cell Junction in drug absorption.
2. (a) Write about mucus structure and composition.
(b) Explain the Lymphatic transport of drugs with suitable examples.
3. (a) Explain gene targeted diseases and the importance of gene therapy.
(b) Write about gene expression system.
4. (a) Differentiate genomic, proteomics and bio-informatic.
(b) Importance of gene therapy in Thalassemia and Hemophilla B.
5. Add a note on the following biotechnology based drugs.
(a) Insulin derivative.
(a) Insulin derivative.
(b) Tissue plasminogen activator.
(c) Herceptin.
(c) Herceptin.
6. (a) write the concept used in vaccine development using micro particles.
(b) Mention the antigen adjuvants used in vaccine formulation.
7 (a) Describe antibody-drug conjugate.
(b) Explain drug targeting based on chemical drug delivery approach for brain, eye and liver.
8. Write the principles and procedure involved in the formulation of Liposomes and Noisomes,
