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Scientists' new breakthrough in finding a cure for HIV

Scientists found a protein that flags up Immune Cells harbouring hidden pools of the AIDS-causing virus – one of the reasons a cure has remained elusive.
Scientists' new breakthrough in finding a cure for HIV

While current drugs can keep HIV at bay, a few cells remain infected, so the disease cannot be cured.
Roughly one in a million CD4 T cells in an individual receiving antiretroviral therapy is latently infected.
In lab experiments on the blood samples of 12 HIV patients his researchers analysed immune cells called CD4 T that produced a green fluorescent protein when they were infected.
Scientists' new breakthrough in finding a cure for HIV
Dr Monsef Benkirane
Credit: CNRS IGH
This pinpointed the CD32a lymphocytes – white blood cells that protect the body from infection – that were only expressed on the surface of dormant HIV cells.
Virologist Dr Monsef Benkirane, of Montpellier University in France, said: ‘The persistence of the Hiv Reservoir in infected individuals is a major obstacle to the development of a cure for HIV-1.”
‘Our discovery that CD32a lymphocytes represent the elusive HIV-1 reservoir may lead to insights that will facilitate the specific targeting and elimination of this reservoir.’
Scientists' new breakthrough in finding a cure for HIV

Credit: Getty Images
Professor Douglas Richman, of the Centre for AIDS Research at California University in San Diego who reviewed the study for the journal, said: ‘This highly selective marker for latently infected CD4 T cells could at last allow researchers to investigate the mysterious mechanisms of latency – without needing to find the one cell of interest in a million..
‘The marker might also be helpful in analysing the success of candidate drugs that aim to target this reservoir.’
Writer: Rob Waugh for Metro.co.uk


This post first appeared on Grabey | Weird News, Funny News, Strange News, Anything, please read the originial post: here

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