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Overdosing on Chilly and Flu Drugs


Over-the-counter (OTC) cough and Chilly medicines are broadly accessible, low-cost, and will help relieve some signs of higher respiratory infections and the flu. Whereas they’ve some advantages, these medicines carry a threat of overdosing.

Overdosing of OTC chilly and flu treatments is commonly unintended—on account of errors like misreading product labels or dosing. Generally, these medicines are additionally deliberately abused.

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How an Unintentional Overdose Occurs


Overconsumption of medication present in chilly and flu treatments, corresponding to acetaminophen, non-steroidal anti-inflammatories, dextromethorphan, pseudoephedrine, and antihistamines, pose well being dangers. Utilizing these medicines with alcohol may result in overdosing.

There are a number of causes that unintended overdoses can occur with these medicines.

Overdosing on OTC chilly and flu medicines can occur when somebody ignores dosing suggestions and takes no matter dose they deem obligatory. Some folks could take bigger or extra frequent doses in an effort to beat sickness quicker.

And other people could misinterpret a product label or measure the dose incorrectly on account of easy human error.

Taking totally different OTC chilly and flu treatments could cause an overdose in the event that they comprise among the identical components. For instance, if you happen to have been to take a multi-symptom treatment like NyQuil together with Tylenol (or Tylenol Additional Power) for fever and ache, you possibly can overdose on acetaminophen, which is in each merchandise.

Taking an excessive amount of acetaminophen can probably trigger liver harm. This threat is even increased with alcohol. In accordance with analysis revealed within the Journal of Medical and Translational Hepatology, acetaminophen overdose accounts for greater than 50% of overdose-related acute liver failures in the US.

Methods to keep away from these errors embrace:

  • Learn the product labels
  • Avoiding co-administration of treatments with the identical components
  • Restrict your self to the really helpful dose
  • Do not drink alcohol once you’ve been taking chilly and flu medicines

Chilly/Flu Medicines and Children

A 2015 report within the journal Pediatrics in Overview concluded that OTC preparations aren’t any simpler in treating cough and chilly signs in comparison with placebo and that the merchandise haven’t been confirmed to be protected and efficient in younger youngsters.

The U.S. Meals and Drug Administration (FDA) asserts that almost all youngsters will get better from chilly and flu on their very own with out the necessity for medication and advises in opposition to using these medicines in youngsters beneath 4 years previous except a health care provider particularly tells you to take action.

Indicators of Unintentional Overdose

Although it’s possible you’ll by no means anticipate a chilly and flu treatment overdose, they will simply occur. It is vital to acknowledge the indicators of overdose.

Signs of a possible overdose of OTC chilly and flu treatment embrace:

  • Extreme tiredness or lethargy
  • Excessive dizziness or drowsiness
  • Sudden anxiousness or jitteriness
  • Confusion
  • Stomach ache
  • Labored or shallow respiratory
  • Lack of urge for food
  • Nausea or vomiting
  • Speedy coronary heart price
  • Blurred imaginative and prescient
  • Dilated pupils
  • Darkish-colored urine
  • Unresponsivenessness

Name Poison Management at 1-800-222-1222 and search emergency care if you happen to assume you have given your self or your baby an excessive amount of chilly and flu treatment.

Medicine Abuse

Previously, codeine and alcohol contained in lots of OTC cough syrups have been abused.

As a public well being security measure, alcohol is just not a element of most OTC treatments, whereas codeine has been categorized managed substance. Merchandise containing 90 mg or extra of codeine, like Tylenol 3, are Schedule III managed substances.

Some folks abuse OTC chilly, cough, and flu treatments containing dextromethorphan (DMX). These merchandise are available all through the US in syrup, pill, and powder type.

The abuse of DMX is commonest amongst eighth to twelfth graders. When swallowed or snorted in extra, DMX could cause hallucinogenic results much like the anesthetic drug ketamine or the road drug phencyclidine (often known as PCP or “angel mud.”) Relying on how a lot is taken, the consequences can final for so long as six hours or much more.

The overuse of DMX is related to an array of negative effects, together with:

  • A sense of floating
  • Confusion and disorientation
  • Impaired judgment
  • Blurred imaginative and prescient
  • Lack of coordination
  • Slurred speech
  • Dizziness
  • Extreme sweating
  • Hyperactivity
  • Hallucinations
  • Speedy or pounding heartbeats
  • A drop in physique temperature
  • Sizzling flashes
  • Diarrhea
  • Stomach ache
  • Nausea and vomiting
  • Unconsciousness

An overdose of DMX can result in extra severe signs, together with seizures, cerebral hemorrhage (bleeding within the mind), everlasting mind harm, and even demise.

Repeated abuse of DXM at excessive doses may trigger a situation often called chemical psychosis wherein an individual loses contact with actuality. Referred to by some as “poor man’s psychosis,” the DMX-induced dysfunction (characterised by paranoia, delusions, hallucinations, and disassociation) has been identified to result in impulsive and even violent acts, together with assault and self-harm.

Indicators of Chilly/Flu Medicine Abuse

Since DMX abuse is basically hidden, you will need to acknowledge the indicators of overdose.

For those who suspect that somebody has overdosed on DMX, name 911 if there are any of the next signs:

  • Excessive disorientation or drowsiness
  • Blueish lips, fingernails, or pores and skin
  • Vomiting
  • Seizures
  • Very sluggish or very fast heartbeats
  • Sluggish, shallow, or labored respiratory
  • Unconsciousness
  • No respiratory

Till assist arrives, name Poison Management 1-800-222-1222 for directions on what to do.

A Phrase From Verywell

To stop abuse in your loved ones, educate your youngsters concerning the risks of DMX, monitor their actions, maintain observe of all chilly and flu medicines within the house, and keep away from stockpiling medicines containing DMX. And if you happen to’re self-treating a chilly, make sure you rigorously learn and observe product directions and solely deal with the signs you might have.

Continuously Requested Questions

  • How a lot NyQuil could cause an overdose?

    For NyQuil Chilly and Flu Nighttime Aid, don’t take greater than 4 doses in 24 hours. See the instructions on the field for the right dosage for adults and kids.

  • What do you have to do if you happen to overdose on chilly and flu medication?

    In instances of overdose, get emergency medical assist or name Poison Management at 1-800-222-1222. It is vital to get instant medical care, even if you happen to do not discover any signs but.

Verywell Well being makes use of solely high-quality sources, together with peer-reviewed research, to assist the information inside our articles. Learn our editorial course of to study extra about how we fact-check and maintain our content material correct, dependable, and reliable.
  1. Spangler DC, Loyd CM, Skor EE. Dextromethorphan: a case research on addressing abuse of a protected and efficient drug. Subst Abuse Deal with Prev Coverage. 2016;11(1):22. doi:10.1186/s13011-016-0067-0

  2. Yoon E, Babar A, Choudhary M, Kutner M, Pyrsopoulos N. Acetaminophen-induced hepatotoxicity: A complete replace. J Clin Transl Hepatol. 2016;4(2):131-42. doi:10.14218/JCTH.2015.00052

  3. Lowry JA, Leeder JS. Over-the-counter medicines: Replace on cough and chilly preparations. Pediatr Rev. 2015;36(7):286-97. doi:10.1542/pir.36-7-286

  4. U.S. Meals and Drug Administration. When to offer youngsters medication for coughs and colds.

  5. U.S. Drug Enforcement Company Diversion Management Division. Title 21 United States Code (USC) Managed Substances Act: Part 812 Schedule of managed substances.

  6. Antoniou T, Juurlink DN. Dextromethorphan abuse. CMAJ. 2014;186(16):E631. doi:10.1503/cmaj.131676

  7. Martinak B, Bolis RA, Black JR, Fargason RE, Birur B. Dextromethorphan in cough syrup: The poor man’s psychosis. Psychopharmacol Bull. 2017;47(4):59-63.

  8. U. S. Nationwide Library of Medication. DailyMed. Vicks NyQuil Chilly and Flu Nighttime Aid.


By Kristina Duda, RN

Kristina Duda, BSN, RN, CPN, has been working in healthcare since 2002. She focuses on pediatrics and illness and an infection prevention.  



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