The Tennessee Titans will lock horns with the Indianapolis Colts in Week 5 of the NFL season at Lucas Oil Stadium on Sunday. Kickoff is at 1 p.m. ET.

This prediction for Sunday’s NFL matchup between the Titans and Colts is from Dimers.com, a reliable source for sports betting predictions, along with our best bet of the game.

Explore the interactive widget below to see the latest spread, over/under, and moneyline betting odds and probabilities for the Titans-Colts game at Lucas Oil Stadium.

RELATED NFL BETTING STORIES

NFL Week 5 betting: Odds, predictions, best bets, and promos

NFL Week 5 odds: Spreads, over/unders, and moneylines for every game this week

Best Kentucky online sports betting apps for NFL Week 5 and NCAAF Week 6

Best Kentucky sports betting promos for NFL Week 5 & NCAAF Week 6

Titans vs. Colts betting preview

Game details

• Teams: Tennessee Titans vs. Indianapolis Colts
• Date: Sunday, October 8, 2023
• Kickoff: 1 p.m. ET
• Location: Lucas Oil Stadium

Odds

• Spread: Titans -2.5 (-110), Colts +2.5 (-110)
• Moneyline: Titans -130, Colts +120
• Total: Over/Under 43.5 (-110/-110)

The odds and lines featured here are the best available from selected sports betting sites at the time of publication and are subject to change.

Expert prediction: Titans vs. Colts

Leveraging cutting-edge data analysis and advanced algorithms, Dimers.com has performed 10,000 simulations of Sunday’s Titans vs. Colts matchup.

According to Dimers’ independent predictive analytics model, the Titans are more likely to beat the Colts at Lucas Oil Stadium. This prediction is based on the model giving the Titans a 57% chance of winning the game.

Furthermore, Dimers predicts that the Colts (+2.5) have a 58% chance of covering the spread, while the 43.5-point over/under has a 52% chance of staying under.

These predictions and probabilities are accurate at the time of publishing but are subject to change.

Titans vs. Colts best bet

Our top pick for the Titans vs. Colts Week 5 NFL game is to bet on the Colts +2.5 (-110).

To place your wager with Bet365, simply click here .

Our expert betting tips are based on detailed modeling and valuable wagering intelligence, designed to deliver you the best possible plays.

Score prediction for Titans vs. Colts

Dimers’ predicted final score for the Tennessee vs. Indianapolis game on Sunday has the Titans winning 22-20.

This expert prediction is based on each team’s average score following 10,000 game simulations, offering a glimpse into the potential outcome.

Titans vs. Colts player props

Prop bets are an exciting way to wager on Sunday’s game without necessarily betting on its outcome.

This article features the most likely first and anytime touchdown scorers for the Titans and Colts.

Tennessee’s Derrick Henry is most likely to score the first touchdown in Titans vs. Colts, according to DimersBOT.

DimersBOT gives Henry a 14.0% chance of scoring the first TD at Lucas Oil Stadium. The Titans RB has a 53.4% chance of scoring an anytime touchdown.

First touchdown scorer prediction

Tennessee Titans

• Derrick Henry: 14.0% probability
• DeAndre Hopkins: 9.6% probability
• Treylon Burks: 6.2% probability
• Ryan Tannehill: 5.4% probability
• Tyjae Spears: 4.8% probability

Indianapolis Colts

• Jonathan Taylor: 10.2% probability
• Anthony Richardson: 7.9% probability
• Michael Pittman: 6.5% probability
• Zack Moss: 5.2% probability
• Kylen Granson: 4.1% probability

Anytime touchdown scorer prediction

Tennessee Titans

• Derrick Henry: 53.4% probability
• DeAndre Hopkins: 38.6% probability
• Treylon Burks: 25.5% probability
• Ryan Tannehill: 23.5% probability
• Tyjae Spears: 21.4% probability

Indianapolis Colts

• Jonathan Taylor: 40.9% probability
• Anthony Richardson: 35.4% probability
• Michael Pittman: 28.3% probability
• Zack Moss: 22.8% probability
• Kylen Granson: 19.0% probability

NFL today: Titans vs. Colts

Get ready for Sunday’s game between the Titans and Colts in Week 5 of the NFL season at Lucas Oil Stadium, which is scheduled to start at 1 p.m. ET. To add an extra level of excitement, consider exploring the best parlay bets today.

We emphasize that all of the NFL predictions in this preview are derived from 10,000 data-driven simulations of the Titans vs. Colts matchup, and they are correct at the time of publishing to help you make better decisions when placing bets at online sportsbooks.

Please remember to gamble responsibly and consult reliable sources for accurate and up-to-date information when making online betting decisions.

Think you know Bills football? Play the syracuse.com Prop Bet Showdown for a chance to win prizes!

Dimers.com provides exclusive sports betting content to Syracuse.com, including sports news, picks, analysis and sportsbook promotions. Please wager responsibly.

If you or a loved one has questions or needs to talk to a professional about gambling, call 1-800-GAMBLER or visit 1800gambler.net for more information.

ABOUT THE AUTHOR

Mac Douglass | Dimers.com

Mac Douglass is the Senior Sports Betting Editor at Cipher Sports Technology Group. In addition to reporting on the sports betting industry for several news outlets across the US, Mac provides predictive analysis for the NFL, college football, and several other sports for Dimers and Stats Insider.