A Gold Coast dream home worth more than $1 million is up for grabs in a new Lottery prize draw raising money for Queensland's hospitals and medical research.

Hosted by the Mater Foundation, the lottery will be drawn on December 23, with millions of dollars worth of prizes on offer.

The $1.45 million-valued Hamptons style home to be given to one lucky winner boasts river views, four bedrooms, two bathrooms, a lap pool and private pontoon.

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"This is what many people dream of," Mater Foundation ambassador Laura Geitz said.

"What else could you want in a Gold Coast waterfront home?"

Along with the house, winners get a new Tesla, a sports boat, and $1 million in cashable gold.

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Tickets for the lottery are just $2 each.

"Buying a ticket and winning this home could change your life," Geitz said.

All the money raised will go straight back to Queensland's health system and will fund potentially life-changing research.

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One new mother helped by Mater Lotteries funding is Sierra Olave, who gave birth to her twins at just 23 weeks pregnant.

The twins had a rare condition called twin-to-twin transfusion syndrome, which affects the mother's placenta.

"At 19 weeks I had to have an operation while they were still in my belly, to better their chance of survival," Ms Olave said.

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Now the twins are happy and healthy after a full recovery.

"These two girls are absolutely flourishing. We are meeting milestones."

Tickets for the lottery are available through the Mater Lotteries website.