More resources must be handed to the North after Brexit, Andy Burnham will say.
Voters who backed Leave were protesting as much about centralised power in Westminster as they were about Brussels bureaucracy, the Greater Manchester Mayor says.
Now neglected regions must get more power to build their own future as the UK quits the EU next year.
The Labour ex-cabinet minister will say: “The referendum result was as much an instruction for Westminster to review its relationship with the rest of England as it was for it to review its relationship with Brussels.
“What found its voice was the deeply held sentiment that our over-centralised political system neglected some areas in favour of others.
“But that uncomfortable truth has been allowed to be overlooked in all the to-ing and fro-ing over Europe. To leave it unanswered is dangerous.
“If the phrase ‘take back control’ is to mean anything, it must mean substantial devolution of power and resources out of Westminster.”
In the speech, backed by the Northern Powerhouse Partnership, he will call for “a big reset of our own political system” whatever the outcome of Brexit negotiations.
He will also signal support for delaying Brexit if no deal looks likely to be agreed before the March exit, as well as potentially backing a second referendum on the departure terms.
