When a biologist’s husband goes missing, his wife must embark on a dangerous mission into the unknown to save him. From “Ex-Machina” writer and director Alex Garland, “Annihilation” hits theaters in February.

After a group of soldiers enter an environmental disaster zone known as Zone X, only one returns home alive. But his homecoming is turned in circles and it is soon his wife Lena (Natalie Portman) to save his life.

Natalie Portman in “Annihilation”

Lena, a biologist, volunteers for a second expedition to Area X to figure out what the Area became and how it came to be like this.

She joins three other women, an anthropologist (Gina Rodriguez), a surveyor (Tessa Thompson), a linguist (Tuva Novotny) and the leader of the group, a psychologist (Jennifer Jason Leigh).

“Annihilation” is based on the novel of the same name by Jeff VanderMeer, the first book in his award-winning “Southern Reach Trilogy.”

Directed and written by Alex Garland, the film is equal parts sci-fi thriller and adventure that will take you on a journey that just keeps getting weirder and weirder.

Speaking about the film’s premise, Garland said, “The basic underlying premise is the journey from suburbia to psychedelia. We’re going to start in the suburbs and end up in psychedelia. That was the underlying principle.

“We wanted to build [the film] from normality to something very strange and gaining the strangeness,” he added. “There are these moments of propulsion where suddenly you fall into another level of weirdness, then another level and [we] just keep pushing it.

“Annihilation” hits theaters on February 23.

Jennifer Jason Leigh in “Annihilation”

Starring: Natalie Portman, Jennifer Jason Leigh, Gina Rodriguez, Tessa Thompson, Tuva Novotny, Oscar Isaac