During a game earmarked for the youth, 33-year-old Giancarlo Stanton came through with the biggest swing of the evening.

The Yankees slugger blasted a two-run home run Tuesday night that represented the 400th of his career, becoming the fourth-fastest in MLB history, in terms of games played, to reach that milestone.

In the sixth inning of a series-opening game in The Bronx against the Tigers, Stanton stepped into a slider from José Cisnero and rocketed it an estimated 451 feet to left-center to give the Yankees a 3-1 lead and give himself a significant piece of baseball history.

It took Stanton 1,520 games to reach No. 400, only beaten by Mark McGwire (1,412), Babe Ruth (1,475) and Alex Rodriguez (1,489).

Stanton, who became the 10th player to accomplish the feat as a Yankee, took a curtain call and lifted his helmet to the fans, who stood and clapped in recognition.

Anthony Volpe used a timeout at the plate to give Stanton a bit more time to receive his applause.

On a night on which Jasson Dominguez made his home debut, Stanton reminded everyone the old guys are still swinging, too.