If you Cheat in South Park: The Fractured but Whole, Cartman will show up to yell at you, like a far fouler version of Nintendo’s Mr. Resetti digging up out of the ground to chastise you for changing the date in Animal Crossing.
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Of course, the definition of “cheating” is a bit murky in the context of a single-player RPG. In this case it means finding a password ahead of where you’re actually supposed to discover it in-game, whether by looking it up or bringing back knowledge from a previous playthrough. Certainly, you could never guess that Cartman would lock his hidden basement base behind a password like “Fuck You Mom.” That one’s impossible to crack.