Elizabeth Anne "Lizzy" Caplan (5' 4" (1,63 m) born June 30, 1982) is an American actress. She is known for her roles in films such as Mean Girls (2004), Cloverfield (2008), Hot Tub Time Machine (2010), and Bachelorette (2012). Her most notable television roles include Marjee Sorelli in Related (2005–2006), Kat Warbler in The Class (2006–2007), Amy Burley in True Blood (2008), Casey Klein in Party Down (2009–2010), and Virginia Johnson in Masters of Sex (2013–present).
Caplan was born and raised in a Reform Jewish family in Los Angeles, California. Her father was a lawyer and her mother was a political aide. Her mother died when Caplan was 13 years old. Caplan attended Alexander Hamilton High School, and was a student at the school's Academy of Music. She first focused on Playing the piano, then later decided to pursue drama. She graduated in 2000.
Caplan began her acting career in 1999, playing a minor role on the critically acclaimed Series Freaks and Geeks. She then had a series of guest appearances on numerous shows, and Appeared in Jason Mraz's music video "You and I Both". In 2001, she played Tina Greer in an episode of Smallville, and reprised her role on the show in 2003. She appeared in two episodes of the ABC series Once and Again. In 2003, she starred in the television series The Pitts, playing Faith Pitt. She gained wider notice for playing Janis Ian in the 2004 film Mean Girls. She played Avery Bishop in the second season of Tru Calling.
In 2005, Caplan played troubled sister Marjee Sorelli in Related, a one-hour comedy-drama on The WB that was canceled after one season. In 2006, she starred as Sara Weller in the thriller film Love is the Drug and was named one of "10 Actors to Watch" by Variety. After Related ended, Caplan was cast in the CBS sitcom The Class, which premiered in September 2006 and lasted for one season. She played Kat Warbler, one of several elementary school friends that reunite after 20 years.
In 2008, Caplan played Marlena Diamond in the film Cloverfield and was nominated for a Saturn Award for Best Supporting Actress. She also appeared as Ami in the romantic comedy My Best Friend's Girl. Later that year, she guest starred as Amy Burley on the HBO vampire show True Blood. She is the voice of Faith Pitt in the animated version of The Pitts, which premiered in 2009. She also appeared in the critically acclaimed Starz ensemble comedy Party Down, playing a struggling comedian who is part of a catering crew. In 2010, she appeared in 127 Hours.
In early 2012, Caplan premiered two films at the Sundance Film Festival: Save the Date and Bachelorette. Also in 2012, she has appeared as Julia in several episodes of the Fox sitcom New Girl. In 2013, she began playing 1960s human sexuality pioneer Virginia Johnson on the Showtime series Masters of Sex. The first season aired to critical acclaim and strong ratings. Caplan also provided her own vocals for a cover version of the song "You Don't Know Me" in the Masters of Sex episode "Phallic Victories". Her performance on the show has been well reviewed, and on July 10th 2014, she was nominated for the Primetime Emmy Award for Outstanding Lead Actress in a Drama Series.
Caplan dated Matthew Perry. She is the godmother of the daughter of actress Busy Philipps and screenwriter Marc Silverstein.