Watch this Thursday night matchup here!

The final Thanksgiving Day game will feature another two teams fresh off a loss, with the Buffalo Bills (6-4) on the road against the New Orleans Saints (5-5) on Thursday Night Football.

The Saints lead the all-time series between these teams, 7-4, and they’ve also won the last five times they faced off. They haven’t played each other since Nov. 2017, with Buffalo losing big at home, 47-10, and the last time they played in New Orleans was in Oct. 2013.

Here’s everything you need to know about tonight’s game.

Buffalo Bills vs. New Orleans Saints

TV Schedule

Game time: 8:20 PM EST

Channel: NBC

Date: Thursday, November 25, 2021

Location: Caesars Superdome | New Orleans, LA

Announcers: Mike Tirico, Drew Brees, Michele Tafoya (field reporter)

Radio: Westwood One | SIRIUS: 82 (Buf.), 85 (NO), 88 (National) | XM: 226 (Buf.), 227 (NO), 88 (National) | SXM App: 803 (Buf.), 822 (NO), National (88)

Online Streaming

Peacock TV | FuboTV

Odds

Buffalo Bills: -6 (-250)

New Orleans Saints: +6 (+200)

Over/Under: 45

BLG pick: Bills -6

SB Nation Blogs

Bills: www.BuffaloRumblings.com

Saints: www.CanalStreetChronicles.com

Open thread: discuss Thursday night’s game in the comments below.