Jimmy Butler will miss his second consecutive game with a sprained right wrist when the 76ers host the San Antonio Spurs on Wednesday night at the Wells Fargo Center.
Ben Simmons (upper respiratory infection) and Joel Embiid (back tightness) are listed as questionable.
This is the sixth game Butler will miss since being acquired from the Timberwolves in November.
He missed two with a strained groin and two others with an upper respiratory infection.
Corey Brewer, who signed a 10-day contract with the Sixers on Jan. 15, started in Butler’s place against the Houston Rockets on Monday and scored 11 points in the 121-93 victory.
Embiid is tied with Utah Jazz center Rudy Gobert atop the NBA with 39 double-doubles.
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