The Reds played two pre-season games in Mexico last month, falling 6-3 to Club America before defeating Cruz Azul 4-1.
"I think its valuable for our group to play a Mexican League opponent," said coach Greg Vanney.
The Reds then opened their Major League Soccer regular season with a 2-0 loss to the visiting Columbus Crew on Saturday.
One of the top clubs in Liga MX, Monterrey-based Tigres has won the league championship six times, including last year, and currently sits fourth in the standings after 10 games.
One of the Tigres' biggest threats is French forward Andre-Pierre Gignac — a player Toronto is well aware of.
Some times they'll use him as a second forward and (Enner) Valencia will stay high and he'll kind of threaten space and Gignac will drop as a midfielder and arrive in the box.
The Reds are on a bye in MLS this week before returning to action on March 17 against the Impact in Montreal.
- LARSON: Toronto FC must turn Tigres test into controlled chaos amid nasty ...Toronto Sun
- Toronto FC vs. Tigres: What to watch forWaking The Red (blog)
- Toronto FC vs Tigres UANL CONCACAF Quarterfinals– Preview, Prediction March 7 ...FutnSoccer
- Toronto FC vs. Tigres 2018 live stream: Time, TV channel, and how to watch ...SB Nation
- Four reasons why Toronto FC will beat TigresWaking The Red (blog)
- Toronto FC Prediction League 2018: Round 4 (vs. Tigres)Waking The Red (blog)
- Countdown: Toronto FC v UANL TigresRedNation Online
- Warshaw: 3 matches, 3 paths to CONCACAF Champions League victory for MLSMLSsoccer.com
- How Toronto FC have been scouting Tigres star Andre-Pierre GignacMLSsoccer.com