(CNN) -- Serena Williams' absence has not stopped America's Women from enjoying their most successful US Open for 15 years.
Madison Keys' victory over fourth seed Elina Svitolina Tuesday ensured four American Women progressed to the quarterfinals in New York -- the best performance by the US since 2002, when five made it into the last eight.
Remarkably, ninth seed Venus was part of that American quintet of Lindsay Davenport, Jennifer Capriati, Monica Seles and sister Serena 15 years ago and is aiming for a first title at Flushing Meadows since 2001.
Unseeded Stephens -- who has risen 851 places in the rankings since August -- will be first on Arthur Ashe on Tuesday, taking on Latvia's Anastasija Sevastova, the conqueror of Maria Sharapova in the last 16.
Vandeweghe, who is seeded 20th, will play in her first US Open quaterfinal and has the ominous task of toppling world No.1 Karolina Pliskova.
- And then there were 4: Keys gives US half of Open QF spotsSan Francisco Chronicle
- Four American women reach US Open quarterfinals for the first time since 2002Los Angeles Times
- The Latest: Keys beats Svitolina; 4 US women in Open QFsYahoo Sports
- Keys makes it four for American women at US OpenYahoo Sports
- US Open: Madison Keys makes it four American women in quarter-finalsBBC Sport
- Keys advances to US Open quarter-finalsSport24
- US women comprise half of quarterfinal field at OpenESPN
- Madison Keys becomes 4th American woman to reach 2017 US Open quarterfinalsSB Nation
- Stats Corner: American quartet soars into US Open quarterfinalsWTA Tennis
