Inflammation is the first line of defense against pathogenic organism in humans and animals but is it also involved in the pathophysiology of many chronic diseases: Rheumatoid Arthritis, irritable bowel syndrome, ulcerative colitis, obesity, neurodegenerative Disease of aging, diabetes, allergic diseases, cancer, cardiovascular diseases,…. Omega 3 fatty acids DHA and EPA are found in significant quantities in fish, seafood and algae from the microplankton. Many studies have shown that DHA can be useful in prevention and therapy and some of the chronic inflammatory disease. The mechanism of action is very complex but it has been elucidated earlier (Calder 2015). Animal experiments demonstrated benefits of omega 3 supplementation in animal models of rheumatoid arthritis, inflammatory bowel disease and asthma. Clinical trials in humans have also demonstrated benefits in rheumatoid arthritis, neurodegenerative disease ( retinal degeneration and Alzheimer’s disease), tissue injury-induced inflammation and postoperative pain (Lorente-Cebrian et al 2015).
Another recent study suggested that omega-3 fatty acids can successfully reduce gingival inflammation and pocket depth in patients with periodontitis and therefore can be used in the prevention or the management of this disease (Deore at al 2014).
Needless to say our companions suffer from similar chronic inflammatory disease and can also benefits from omega-3 DHA supplementation.