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Supernutrient (SAMe)

SAMe ( a-adenosylmethionine) or sam or adomet

liver supernutrient

reverses the destructive effect of most of the chemicals and alcohols.

SAM was first discovered in Italy by G. L. Cantoni in 1952. naturally occurring compound that is found in almost every tissue and fluid in the body.

SAMe plays a role in the immune system, maintains cell membranes, and helps produce and break down brain chemicals, such as serotonin, melatonin, and dopamine. It works with vitamin B12 and folate (vitamin B6). Being deficient in either vitamin B12 or folate may reduce levels of SAMe in your body.

mainly involves in 2 functions
1. methylation
2.trans-sulfuration

helps in
Maintaining mitochondrial function
 Prevents DNA mutations(cancer treatment)
 Restores cellular membrane fluidity so that cell receptors become better able to bind hormones and other factors

one result of trans-sulfuration is transformation in to glutathione,most vital substance in the liver

gluthione is an natural antioxidant for liver



research studies states that taking SAMe externally helps in reducung the depression with less side effects when compared to other drugs available .A number clinical trials show that SAMe may reduce pain and inflammation in the joints, and researchers think it may also promote cartilage repair, although they are not clear about how or why this works. In several short term studies (ranging 4 - 12 weeks), SAMe supplements were as effective as nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen in adults with knee, hip, or spine osteoarthritis. SAMe was as effectives as these medications in lessening morning stiffness, decreasing pain, reducing swelling, improving range of motion, and increasing walking pace


liver contains third highest amount of SAMe in the body (after adrenal and penal glands)
plays an important role in the regeneration.

People with liver disease often cannot synthesize SAMe in their bodies, and some preliminary studies suggest that taking SAMe may help treat chronic liver disease caused by medications or alcoholism. A study  with alcoholic liver cirrhosis (liver failure) found that SAMe treatment for 2 years improved survival rates and delayed the need for liver transplants better than placebo. Other studies show that SAMe may help normalize levels of liver enzymes in people with liver disease. Studies in mice show that SAMe protects against and can also reverse liver damage.



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This post first appeared on Pharmacy Window, please read the originial post: here

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Supernutrient (SAMe)

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