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Can Stem cells clear a roadblock towards diabetes treatment? The cutting edge scientific excellence has allowed major upgradation in the cellular therapies through inclusion of wide variety of degenerative diseases, which currently have no medical solution, like Diabetes, neurodegenerative disorders, etc. Likewise, recently in a unique experiment, scientists could develop a method through which future predictions related to diabetes or its early detection can be achieved. Lot of attention has been received for the application of terahertz waves to biosense, certain specific molecular vibrations and rotations that are directly linked with the pre-establishment of diabetes. In the preclinical analysis, the technique has found to be certain limitations in its applications, due to its strong water absorption; however, later on different modifications have been adopted to make it a success, in early detection of a pre-diabetic state. Application of the proposed technique, along with use of autologous stem cells from patients own body is thus, believed to be the ideal combination to offer quick regeneration of pancreatic beta cells through a minimally invasive manner. Adult stem cells are considered to be naïve version of tissue specific cells, and are found to be stored almost in every mature organ of our body. Various experiments could suggest their role in routine wear and tear of the body; especially through a differentiation into host specific cells that are lost in the process. In case of diseased condition, like diabetes; their number renders to be insufficient to make up for the tremendous cellular loss and thus, need immediate supply of additional stem cells to fight against the condition. Experts have shown that stem cells isolated from our own body tissues, especially fat are the most potent sources to be used for treatment of diabetes, due to their ability to secrete growth factors, which stimulate these resident progenitor stem cells of pancreas. Besides, strong signals are generated immediately after the infusion of stem cells in the body, which guide cells from other sources of our body to reach to the site of injury; which can help in faster healing. In certain diabetic condition, like type 1 diabetes, wherein body’s immune system has to be regulated from being dangerous to be beneficial to pancreas; stem cells have expressed promising role; thus, diabetes mellitus can be treated using immune tolerance properties of stem cells, without the need for lifelong anti-rejection drugs. Thus, the ability to offer stem cell therapy platform to regenerate more insulin producing native pancreatic cells is proven through enough preclinical as well as clinical phase I and II studies and is being admired to be a better option for other invasive treatments, like pancreatic transplants or surgery.
2018-11-30 09:44
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