Tim Sandle has written an article for Infectious Disease Hub.
Here is an extract:
The new research strand aims to trigger human cells to become effective at killing M. tuberculosis cells by harnessing RNA sensors. The aim is to enhance the detection of invading pathogens and to increase the possibility of the body’s immune system in killing the invaders before they can secrete effector proteins. RNA sensors are part of the innate immune system and they are initiated by recognition of pathogen-associated molecular patterns. Such recognition initiates signalling cascades that culminate in a coordinated intracellular innate immune response designed to control infection.
The reference is:
Sandle, T. (2019) Harnessing RNA sensors inhibits growth of tuberculosis bacterium, Infectious Disease Hub, November 2019. At: https://www.id-hub.com/2019/11/26/harnessing-rna-sensors-inhibits-growth-tuberculosis-bacterium/
Posted by Dr. Tim Sandle, Pharmaceutical Microbiology Resources (http://www.pharmamicroresources.com/)